country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-151588

Copy Link Print Information

Anticancer agent 90

Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498).

For research use only. We do not sell to patients.

CAS No.: 2977251-03-7
Formula: C₃₃H₃₂N₂O₁₀S₃
Molecular Weight:712.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

Anticancer agent 90 Chemical Structure

CAS No.: 2977251-03-7

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Anticancer agent 90 (compound 6d) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against two cell lines, SK-MEL-5, OVCAR-4^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cell lines
Concentration:

0-200 μg/mL
Incubation Time:

24 hours
Result:

Showed nontoxic under the doses of 100 μg/mL against FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cells, respectively.

Cell Viability Assay^[1]

Cell Line:

SK-MEL-5, OVCAR-4, and A498
Concentration:

0.01 mM
Incubation Time:

24 hours
Result:

Inhibited SK-MEL-5 and OVCAR-4 cell viability by 30.64% and 30.71%, respectively.

Chemical Information

CAS No. 2977251-03-7
Molecular Weight 712.81
Formula C₃₃H₃₂N₂O₁₀S₃
SMILES

[H][C@]1([C@@H]([C@H]([C@@H](O[C@@H]1COC(C)=O)SC2=C(C(N)=C(S2)C(C3=CC=C(C=C3)C)=O)C4=NC5=C(S4)C=CC=C5)OC(C)=O)OC(C)=O)OC(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Azzam et al. Novel Thiophene Thioglycosides Substituted with the Benzothiazole Moiety: Synthesis, Characterization, Antiviral and Anticancer Evaluations, and NS3/4A and USP7 Enzyme Inhibitions. ACS Omega. 2022 Sep 29;7(40):35656-35667. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote