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  4. Anticancer agent 89

Anticancer agent 89 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity, has high inhibition against the three cell line from ovarian cancer (OVCAR-4), renal cancer (A498), and melanoma (SK-MEL-5).

For research use only. We do not sell to patients.

Anticancer agent 89 Chemical Structure

Anticancer agent 89 Chemical Structure

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Anticancer agent 89 Related Antibodies

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Description

Anticancer agent 89 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity, has high inhibition against the three cell line from ovarian cancer (OVCAR-4), renal cancer (A498), and melanoma (SK-MEL-5)[1].

In Vitro

Anticancer agent 89 (compound 6f) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against three cell lines, SK-MEL-5, OVCAR-4, and A498[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 89 Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cell lines
Concentration: 0-200 μg/mL
Incubation Time: 24 hours
Result: Showed nontoxic under the doses of 90 μg/mL (FRHK-4), 90 μg/mL (Hep2), μg/mL (BGM), 90 μg/mL (Vero), and 100 μg/mL (Huh 7.5), respectively.

Cell Viability Assay[1]

Cell Line: SK-MEL-5, OVCAR-4, and A498
Concentration: 0.01 mM
Incubation Time: 24 hours
Result: Inhibited SK-MEL-5, OVCAR-4, and A498 cell viability by 36.29%, 46.89%, and 36.08%, respectively.
Molecular Weight

777.68

Formula

C32H29BrN2O10S3
SMILES

O=C(C1=C(N)C(C2=NC3=CC=CC=C3S2)=C(S[C@H]4[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@](OC(C)=O)([H])[C@@H](COC(C)=O)O4)S1)C5=CC=C(Br)C=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anticancer agent 89 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 89Anticancer agent89Anticancer agent-89OthersA498benzothiazole-2-thiophene S-glycosideantitumor activityrenal cancer cell lineInhibitorinhibitorinhibit

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