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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
hexosaminidase
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "hexosaminidase" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM .
1
1 Cited Publications
Cat. No.: HY-W011183
CAS No.: 3459-18-5
1
1 Cited Publications
Cat. No.: HY-172458
CAS No.: 473687-20-6
Research Areas:
Z-3578 is an orally active small-molecule antagonist of MrgX2 with potent antipseudoallergic activity, exhibiting a KD value of 729 nM. Z-3578 effectively inhibits mast cell degranulation induced by substance P (SP) and C48/80, suppresses the release of β-hexosaminidase, significantly reduces the release of histamine and TNF-α, and decreases intracellular calcium flux. In a mouse pseudoallergy model, Z-3578 significantly alleviates paw swelling and dye extravasation, and reduces serum histamine levels. Z-3578 can be used for the study of pseudoallergic reactions .
1
1 Cited Publications
Cat. No.: HY-P75808
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HEXB; HEL-248; hexosaminidase Subunit Beta; HCC-7; Beta-hexosaminidase Subunit Beta; Epididymis Secretory Sperm Binding Protein; N-Acetyl-Beta-Glucosaminidase Subunit Beta; Epididymis Secretory Protein Li 111; Beta-N-Acetylhexosaminidase Subunit Beta; Bet
Species:
Mouse
Source:
HEK293
Cat. No.: HY-W009274
CAS No.: 10597-89-4
Synonyms: MurNAc; NAMA
Cat. No.: HY-N2426
CAS No.: 119738-57-7
Target:
Synonyms: ASN90
Target:
Research Areas:
Egalognastat (ASN90) is a selective, brain-penetrant and orally active O-GlcNAcase (OGA) enzyme inhibitor with an IC50 value of 10.2 nM. Egalognastat increases O-GlcNAcylation of intracellular proteins like tau and α-synuclein, preventing their aggregation and toxicity. Egalognastat does not inhibit hexosaminidase (Hex). Egalognastat can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies (e.g., Alzheimer’s disease and Parkinson’s disease) .
Cat. No.: HY-113242
CAS No.: 35176-46-6
Target:
Cat. No.: HY-P1793
CAS No.: 83471-50-5
Research Areas:
Cat. No.: HY-145678
CAS No.: 1417906-42-3
Target:
Research Areas:
α-HNJNAc is a potent, competitive hexosaminidases inhibitor without interfering with other glycosidases .
Cat. No.: HY-P991651
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Research Areas:
Cat. No.: HY-143285
Cat. No.: HY-N15708
CAS No.: 755036-45-4
Synonyms: (R)-(-)-Dichotomine C
Cat. No.: HY-P1793A
Research Areas:
Cat. No.: HY-139733
CAS No.: 2760672-89-5
β-N-Acetyl-D-hexosaminidase-IN-1 is a novel β-N-acetyl-d-hexosaminidase inhibitor with a Ki value of 3.72 μM.
Cat. No.: HY-151544
Cat. No.: HY-N8426
CAS No.: 79004-25-4
Synonyms: Ellisinin A
Target:
Cat. No.: HY-N12261
CAS No.: 138968-86-2
Category:
Target:
Cat. No.: HY-N12116
CAS No.: 1967042-42-7
Target:
Cat. No.: HY-N3815
CAS No.: 921211-29-2
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
