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Cat. No.: HY-N15708

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Dichotomine C

(Synonyms: (R)-(-)-Dichotomine C)

Dichotomine C ((R)-(-)-Dichotomine C) is a β-carboline-type alkaloid with antiallergic effects. Dichotomine C inhibits the release of β-hexosaminidase in RBL-2H3 cells with an IC₅₀ of 62 μM. Dichotomine C inhibits the releases of antigen-IgE-mediated TNF-α and IL-4 in RBL-2H3 cells with IC₅₀s of 19 μM and 15 μM, respectively. Dichotomine C can be used for the study of type I allergic reactions.

For research use only. We do not sell to patients.

CAS No.: 755036-45-4
Formula: C₁₅H₁₄N₂O₄
Molecular Weight:286.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Dichotomine C Chemical Structure

CAS No.: 755036-45-4

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Biological Activity

Description

All TNF Receptor Isoforms :

All Interleukin Related Isoforms :

Chemical Information

CAS No. 755036-45-4
Molecular Weight 286.28
Formula C₁₅H₁₄N₂O₄
SMILES

OC[C@@H](C1=C2C(C3=CC=CC=C3N2)=CC(C(OC)=O)=N1)O
Synonyms

(R)-(-)-Dichotomine C
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sun B, et al. Structures of new beta-carboline-type alkaloids with antiallergic effects from Stellaria dichotoma(1,2). J Nat Prod. 2004 Sep;67(9):1464-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Dichotomine C

All TNF Receptor Isoforms

All Interleukin Related Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dichotomine C Related Classifications

HY-N15708 Related Classifications