PNE-Lyso
PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the agent-induced cell death process.
For research use only. We do not sell to patients.
- Formula: C28H30N2O7
- Molecular Weight:506.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
PNE-Lyso exhibits a strong UV-vis absorption peak at 420 nm in alkaline solution[1].
When PNE-Lyso was treated with Hexs, the fluorescence intensity at 635 nm decreased and blue-shifted (λex = 530 nm), and a new remarkable fluorescence emission at 520 nm appeared (λex = 460 nm), displaying a ratiometric fluorescence signal[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 506.55
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Formula C28H30N2O7
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SMILES
OCC1OC(OC2=CC3=C(C=C4C(O3)=C(CCC4)/C=C/C5=CC=NC=C5)C=C2)C(NC(C)=O)C(O)C1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)