62 Results for "

peripheral vasodilator

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "peripheral vasodilator" in MCE Product Catalog:

94
94 Publications Verification
Cat. No.: HY-B0468
CAS No.: 51-30-9
Synonyms: Isoproterenol hydrochloride
Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
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94
94 Publications Verification
Cat. No.: HY-108353
CAS No.: 7683-59-2
Isoprenaline is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
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94
94 Publications Verification
Cat. No.: HY-108353A
CAS No.: 299-95-6
Isoprenaline hemisulfate is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
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22
22 Cited Publications
Cat. No.: HY-B0131
CAS No.: 745-65-3
Synonyms: Alprostadil; PGE1
Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases .
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11
11 Cited Publications
Cat. No.: HY-B0112
CAS No.: 38304-91-5
Synonyms: U10858
Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM .
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11
11 Cited Publications
Cat. No.: HY-12882A
CAS No.: 23210-58-4
Purity:  99.95%
Synonyms: NP-120 tartrate; RC-61-91 tartrate
Ifenprodil (NP-120) tartrate, a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM) . Ifenprodil tartrate is an α1 adrenergic receptor antagonist. Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 µM). Ifenprodil tartrate has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil tartrate can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .
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11
11 Cited Publications
Cat. No.: HY-12882
CAS No.: 23210-56-2
Purity:  99.94%
Synonyms: NP-120; RC-61-91
Ifenprodil (NP-120), a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM) . Ifenprodil is an α1 adrenergic receptor antagonist. Ifenprodil inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 µM). Ifenprodil has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .
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9
9 Cited Publications
Cat. No.: HY-P0203
CAS No.: 83651-90-5
Synonyms: CGRP (83-119), mouse, rat
α-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies .
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9
9 Cited Publications
Cat. No.: HY-P0203A
Synonyms: CGRP (83-119), mouse, rat TFA
α-CGRP (mouse, rat) TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) TFA can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) TFA has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies .
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6
6 Cited Publications
Cat. No.: HY-P1071
CAS No.: 90954-53-3
Synonyms: Calcitonin gene-related peptide
Target:  

CGRP Receptor

Research Areas:  

Cardiovascular Disease

α-CGRP (human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids. α-CGRP (human) is widely distributed in the central and peripheral nervous system. α-CGRP (human) is a potent vasodilator and has inotropic and chronotropic effects .
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6
6 Cited Publications
Cat. No.: HY-B0358
CAS No.: 52468-60-7
Flunarizine is a potent dual Na +/Ca 2+ channel (T-type) blocker. Flunarizine is a D2 dopamine receptor antagonist. Flunarizine shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects .
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6
6 Cited Publications
Cat. No.: HY-B0358A
CAS No.: 30484-77-6
Flunarizine dihydrochloride is a potent dual Na +/Ca 2+ channel (T-type) blocker. Flunarizine dihydrochloride is a D2 dopamine receptor antagonist. Flunarizine dihydrochloride shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects .
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6
6 Cited Publications
Cat. No.: HY-P1071A
Synonyms: Calcitonin gene-related peptide TFA
Target:  

CGRP Receptor

Research Areas:  

Cardiovascular Disease

α-CGRP (human) (TFA) is a regulatory neuropeptide of 37 amino acids. α-CGRP (human) (TFA) is widely distributed in the central and peripheral nervous system. α-CGRP (human) (TFA) is a potent vasodilator and has inotropic and chronotropic effects .
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1
1 Cited Publications
Cat. No.: HY-B1021
CAS No.: 1617-90-9
Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation . Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research .
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Cat. No.: HY-B0233
CAS No.: 75695-93-1
Synonyms: PN 200-110
Isradipine (PN 200-110) is an orally active and blood-brain barrier permeability L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease .
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Cat. No.: HY-101701
CAS No.: 7237-81-2
Purity:  98.41%
Synonyms: Megrin
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

Hepronicate, a nicotinic acid derivative, is a peripheral vasodilator with blood lipid lowering action. Hepronicate works by improving peripheral circulatory disturbances .
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Cat. No.: HY-B1815
CAS No.: 437-74-1
Synonyms: Xanthinol Niacinate
Target:  

PDGFR

Research Areas:  

Cardiovascular Disease

Xanthinol Nicotinate (Xanthinol Niacinate), a vasodilator, can act directly on the smooth muscle of small arteries and capillaries. Xanthinol Nicotinate expands blood vessels, improves blood rheology and reduces peripheral vascular resistance .
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Cat. No.: HY-B1016
CAS No.: 15421-84-8
Synonyms: AR-12008
Trapidil (AR-12008) is an orally active vasodilator and antiplatelet agent. Trapidil antagonizes platelet-derived growth factor (PDGF), inhibits phosphodiesterase, thromboxane A2 synthesis and pro-inflammatory cytokine production. Trapidil promotes prostacyclin biosynthesis, reduces lipid peroxidation, regulates nitric oxide metabolism, and inhibits cell proliferation and migration. Trapidil exerts tissue-protective effects, regulates bone turnover, and inhibits pyroptosis via the GPX3/Nrf2 pathway. Trapidil is applicable to research related to renal ischemia-reperfusion injury, chronic stable angina, restenosis, meningioma, diabetic cardiomyopathy and peripheral nerve crush injury .
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Cat. No.: HY-B0112R
CAS No.: 38304-91-5
Synonyms: U10858 (Standard)
Minoxidil (Standard) is the analytical standard of Minoxidil. This product is intended for research and analytical applications. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM .
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Cat. No.: HY-119440
CAS No.: 2530-97-4
Target:  

PDGFR

Research Areas:  

Cardiovascular Disease

Xanthinol is a vasodilator that can be used for the study of peripheral and cerebral vascular disorders .
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