Buflomedil
Buflomedil, a vasodilator agent, is an orally active α1A-adrenoceptor antagonist with Kis of 4.06 µM and 6.84 µM for α1A-AR and α1B-AR, respectively. Buflomedil can be used for the study of peripheral circulatory disorders.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 55837-25-7
- 화학식: C17H25NO4
- 분자량:307.38
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
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Biological Activity
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rat α1A-adrenergic receptor 4.06 μM (Ki) |
α1B-adrenergic receptor 6.84 μM (Ki) |
Chemical Information
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CAS No. 55837-25-7
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분자량 307.38
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화학식 C17H25NO4
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SMILES
O=C(C1=C(OC)C=C(OC)C=C1OC)CCCN2CCCC2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. de Backer TL, et al. Buflomedil for intermittent claudication. Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD000988. [Content Brief]
[2]. Limbs International Medicinal Buflomedil (LIMB) Study Group; Leizorovicz A, Becker F. Oral buflomedil in the prevention of cardiovascular events in patients with peripheral arterial obstructive disease: a randomized, placebo-controlled, 4-year study. Circulation. 2008 Feb 12;117(6):816-22. [Content Brief]
[3]. Tang LM, et al. Inhibitory effect of buflomedil on prostate alpha1A adrenoceptor in the Wistar rat. Neurosci Lett. 2004 Sep 2;367(2):224-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Buflomedil Related Classifications
HY-B0484A Related Classifications
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