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Buflomedil hydrochloride 

Cat. No.: HY-B0484 Purity: 99.81%
Handling Instructions

Buflomedil hydrochloride is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.

For research use only. We do not sell to patients.

Buflomedil hydrochloride Chemical Structure

Buflomedil hydrochloride Chemical Structure

CAS No. : 35543-24-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 79 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 72 In-stock
Estimated Time of Arrival: December 31
500 mg USD 108 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Description

Buflomedil hydrochloride is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease. Target: Others Buflomedil hydrochloride is a vasoactive drug used to treat claudication or the symptoms of peripheral arterial disease. In the EU, buflomedil, a vasoactive agent, was indicated for treatment of PAOD symptoms, specifically in patients with stage II PAOD who experience severe pain when walking even relatively short distances. Buflomedil is not currently approved by the US Food and Drug Administration for use in the United States.

Molecular Weight

343.85

Formula

C17H26ClNO4

CAS No.
SMILES

O=C(C1=C(OC)C=C(OC)C=C1OC)CCCN2CCCC2.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 55 mg/mL (159.95 mM)

DMSO : 33.33 mg/mL (96.93 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9082 mL 14.5412 mL 29.0824 mL
5 mM 0.5816 mL 2.9082 mL 5.8165 mL
10 mM 0.2908 mL 1.4541 mL 2.9082 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 110 mg/mL (319.91 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.75 mg/mL (8.00 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.75 mg/mL (8.00 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.75 mg/mL (8.00 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Product Name:
Buflomedil hydrochloride
Cat. No.:
HY-B0484
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