Alprostadil sodium
Based on 22 publication(s) in Google Scholar
Alprostadil sodium is a prostaglandin receptor ligand that exhibits Ki values of 36, 10, 1.1, 2.1, and 33 nM for the EP1, EP2, EP3, EP4, and IP receptors in mice, respectively. It promotes vasodilation and inhibits platelet aggregation, making it a useful vasodilator for investigating peripheral vascular disease.
For research use only. We do not sell to patients.
- CAS No.: 27930-45-6
- Formula: C20H33NaO5
- Molecular Weight:376.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Alprostadil sodium
More- Exploration. 2025 Mar 6;5(3):20240084. [Abstract]
- Nat Cell Biol. 2024 Jul;26(7):1110-1123. [Abstract]
- Acta Pharm Sin B. 2022 Aug;12(8):3427-3447. [Abstract]
- Adv Sci (Weinh). 2026 May;13(25):e15933. [Abstract]
- J Control Release. 2019 May 6;304:233-241. [Abstract]
- Small Struct. 2023 Mar 8.
- Mater Today Bio. 2025 Apr 9:32:101744. [Abstract]
- Mater Today Bio. 2025 Mar 29:32:101719. [Abstract]
- Mater Today Bio. 2022 Dec 5:18:100512. [Abstract]
- Nano Res. 11, 6086-6101(2018).
- Int J Biol Macromol. 2025 May 7:144068. [Abstract]
- Chin Med. 2026 Jan 8;21(1):16. [Abstract]
- Colloids Surf B Biointerfaces. 2024 Feb:234:113680. [Abstract]
- Am J Respir Cell Mol Biol. 2025 Feb 28. [Abstract]
- J Thromb Haemost. 2024 May;22(5):1463-1474. [Abstract]
- Int J Mol Sci. 2022 Oct 15;23(20):12345. [Abstract]
- Cell Rep Methods. 2023 Oct 23;3(10):100599. [Abstract]
- Stem Cell Rev Rep. 2026 Jan 30;22(3):1325-1340.
- J Cardiovasc Pharmacol Ther. 2026 Jan-Dec:31:10742484261452727. [Abstract]
- Pigment Cell Melanoma Res. 2025 Sep;38(5):e70048. [Abstract]
- Curr Proteomics. 2026 Mar 25.
- Oxid Med Cell Longev. 2022 Jan 17:2022:3087198. [Abstract]
Biological Activity
Chemical Information
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CAS No. 27930-45-6
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Molecular Weight 376.46
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Formula C20H33NaO5
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SMILES
O=C(O[Na])CCCCCC[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@@H](O)CCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (22)
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Journal Impact Factor
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Most Recent
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Exploration
Surface-Anchored Ticagrelor Gelatin Nanoparticles-Platelets System for Enhanced Anti-PD-L1 Therapy Response and Boosted Chemotherapeutic Efficacy of Nanomedicines. [Abstract]2025 Mar 6;5(3):20240084. PMID: 40585768 -
Nat Cell Biol
2024 Jul;26(7):1110-1123. PMID: 38997457 -
Acta Pharm Sin B
Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model. [Abstract]2022 Aug;12(8):3427-3447. PMID: 35967283 -
Adv Sci (Weinh)
Activated Platelet-Released Heat Shock Protein 90α Triggers Autophagy-Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis. [Abstract]2026 May;13(25):e15933. PMID: 41732887 -
J Control Release
Platelets as platforms for inhibition of tumor recurrence post-physical therapy by delivery of anti-PD-L1 checkpoint antibody. [Abstract]2019 May 6;304:233-241. PMID: 31071371 -
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Mater Today Bio
2025 Apr 9:32:101744. PMID: 40275952 -
Mater Today Bio
2025 Mar 29:32:101719. PMID: 40236816 -
Mater Today Bio
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction. [Abstract]2022 Dec 5:18:100512. PMID: 36536658 -
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Int J Biol Macromol
FKBP5 inhibitor suppresses platelet activation and thrombosis by inhibiting IKBKE/PI3K/Rap1 pathway. [Abstract]2025 May 7:144068. PMID: 40345291 -
Chin Med
Ferulic acid in combination with ginsenoside Rb1 alleviates myocardial no-reflow by inhibiting platelet HMGB1 release and NET formation. [Abstract]2026 Jan 8;21(1):16. PMID: 41501834 -
Colloids Surf B Biointerfaces
Platelet membrane-derived biomimetic microbubbles with enhanced targeting ability for the early detection of myocardial ischemia-reperfusion injury. [Abstract]2024 Feb:234:113680. PMID: 38101143 -
Am J Respir Cell Mol Biol
GP IIb/IIIa-ICAM-1 Mediated Platelet-Endothelial Adhesion Exacerbates Pulmonary Hypertension. [Abstract]2025 Feb 28. PMID: 40019848 -
J Thromb Haemost
Extracellular vesicles from activated platelets possess a phospholipid-rich biomolecular profile and enhance prothrombinase activity. [Abstract]2024 May;22(5):1463-1474. PMID: 38266680 -
Int J Mol Sci
Coenzyme Q10 Attenuates Human Platelet Aggregation Induced by SARS-CoV-2 Spike Protein via Reducing Oxidative Stress In Vitro. [Abstract]2022 Oct 15;23(20):12345. PMID: 36293203 -
Cell Rep Methods
RECOVER identifies synergistic drug combinations in vitro through sequential model optimization. [Abstract]2023 Oct 23;3(10):100599. PMID: 37797618 -
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J Cardiovasc Pharmacol Ther
Alterations of Platelet MicroRNAs Associated With Dapagliflozin Treatment in Individuals With Type 2 Diabetes Mellitus. [Abstract]2026 Jan-Dec:31:10742484261452727. PMID: 42165435 -
Pigment Cell Melanoma Res
2025 Sep;38(5):e70048. PMID: 40913269 -
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Oxid Med Cell Longev
2022 Jan 17:2022:3087198. PMID: 35082966
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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