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Minoxidil hydrochloride

(Synonyms: U10858 hydrochloride)
11 Cited Publications
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Based on 11 publication(s) in Google Scholar

Minoxidil (U10858) hydrochloride is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil hydrochloride is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM.

For research use only. We do not sell to patients.

  • CAS No.: 69935-18-8
  • Formula: C9H16ClN5O
  • Molecular Weight:245.71
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Minoxidil hydrochloride Chemical Structure
    Minoxidil hydrochloride Chemical Structure
  • Experimental Validation Results for Minoxidil hydrochloride
  • Experimental Validation Results for Minoxidil hydrochloride
  • Experimental Validation Results for Minoxidil hydrochloride
  • Experimental Validation Results for Minoxidil hydrochloride
  • Experimental Validation Results for Minoxidil hydrochloride
  • Experimental Validation Results for Minoxidil hydrochloride
  • Experimental Validation Results for Minoxidil hydrochloride
  • Experimental Validation Results for Minoxidil hydrochloride
CAS No.: 69935-18-8
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Minoxidil hydrochloride Chemical Structure
    Minoxidil hydrochloride Chemical Structure
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    Minoxidil hydrochloride purchased from MedChemExpress. Usage Cited in: Bioact Mater. 2025 Nov 14:57:344-357. [Abstract]

    Customer Validation
     Cell proliferation assay in DPCs and HFSCs treated with DHT (500 μM) and DHT combined with Minoxidil (20 μM), tFNFs (0.25 μM), Que (20 μM), and TQC (tFNFs/Que: 0.25/20 μM) for 24 h.

  • 1/16

    Minoxidil hydrochloride purchased from MedChemExpress. Usage Cited in: Bioact Mater. 2025 Nov 14:57:344-357. [Abstract]

    Customer Validation
     Time-course observations of hair growth of samples at 1, 4, 7, 10, 14, 15, 18, 21, 24, and 28 days (n = 5). The results showed that Minoxidil (5%; topical application, 100 μL per application) treatment, serving as a positive control, led to gradual hair regrowth starting from day 10, with marked hair coverage observed by day 28.

  • 1/16

    Minoxidil hydrochloride purchased from MedChemExpress. Usage Cited in: J Adv Res. 2025 Oct 16:S2090-1232(25)00818-5. [Abstract]

    Customer Validation
     Minoxidil (0.5 mM； 48 h) led to a significant increase in the expression of epithelial differentiation markers in 786-O sccRCC cells.

  • 1/16

    Minoxidil hydrochloride purchased from MedChemExpress. Usage Cited in: J Adv Res. 2025 Oct 16:S2090-1232(25)00818-5. [Abstract]

    Customer Validation
     Minoxidil (0.25-0.5 mM; 48 h) did not cause substantial 786-O ccRCC cell death.

  • 1/16

    Minoxidil hydrochloride purchased from MedChemExpress. Usage Cited in: J Adv Res. 2025 Oct 16:S2090-1232(25)00818-5. [Abstract]

    Customer Validation
     Minoxidil (6 mg/kg; gavage) significantly reduced the Ki-67 index in sccRCC xenograft mouse models.

  • 1/16

    Minoxidil hydrochloride purchased from MedChemExpress. Usage Cited in: J Adv Res. 2025 Oct 16:S2090-1232(25)00818-5. [Abstract]

    Customer Validation
     Minoxidil (6 mg/kg; gavage) significantly reduced the tumor growth rate in sccRCC xenograft mouse models.

  • 1/16

    Minoxidil hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Stem Cell. 2024 Jan 4;31(1):52-70.e8. [Abstract]

    Customer Validation
     Representative bright-field images of ARPKD (ARPKD Epi-17) kidney organoids treated with a concentration gradient of ST034307 and Minoxidil (0.1-5 μM) in the presence of FSK for 3 days. Scale bars, 200 μm.

  • 1/16

    Minoxidil hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Stem Cell. 2024 Jan 4;31(1):52-70.e8. [Abstract]

    Customer Validation
     Minoxidil (i.p.; once daily for 3 weeks) administered at 1 and 5 mg/kg/day reduced the calculated cystic index of ARPKD kidney organoid xenografts from host NSG mice by 18.85% and 33.93%, respectively.

  • Minoxidil hydrochloride