Search Result
Results for "
NIR
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-D1067
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Fluorescent Dye
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Others
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NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .
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- HY-D1066
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Fluorescent Dye
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Others
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NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. NIR-Thiol dinitrobenzenesulfonate responds to thiol with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-Thiol dinitrobenzenesulfonate is capable of imaging endogenously produced thiol in living cells and mice .
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- HY-D1065
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Fluorescent Dye
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Inflammation/Immunology
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NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
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- HY-D1514
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- HY-151890
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Fluorescent Dye
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Cancer
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NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .
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- HY-149422
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Fluorescent Dye
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Neurological Disease
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NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O 2-. O 2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O 2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model .
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- HY-109139
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NIR178; PBF509
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Adenosine Receptor
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Neurological Disease
Cancer
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Taminadenant (NIR178; PBF509) is a highly potent and orally active adenosine A2A receptor (A2AR) antagonist. Taminadenant can antagonize A2AR agonist-mediated cAMP accumulation and impedance responses with KB values of 72.8 nM and 8.2 nM, respectively. Taminadenant reverses motor impairments in several rat models of movement disorders, including catalepsy, tremor, and hemiparkinsonism. Taminadenant can also inhibit tumor growth when combined with Spartalizumab (HY-P9972). Taminadenant reactivate the antitumor immune response .
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- HY-D1500
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Fluorescent Dye
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Others
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Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35) .
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- HY-D1495
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- HY-D1555
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Cy7 DBCO
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Fluorescent Dye
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Others
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Cyanine7 DBCO is a water-soluble NIR fluorescent dye with cycloalkyne moiety .
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- HY-D2215
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Fluorescent Dye
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Cancer
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Mito-CCY is a mitochondria-targeted, NIR-absorbing cryptocyanine probe. Mito-CCY displays a high photothermal conversion efficiency, good biological compatibility in vitro, and photoinduced cytotoxicity in HeLa cells .
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- HY-D1394
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AgAuSe
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Fluorescent Dye
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Others
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AgAuSe QDs (AgAuSe) is a near infrared (NIR) fluorescent quantum dots (QDs), with a bright emission from 820 to 1170 nm. AgAuSe QDs can be used for the research in biomedical imaging and NIR devices .
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- HY-D1375A
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Fluorescent Dye
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Others
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Sulfo-Cy5 amine hydrochloride is a near-infrared (NIR) amino fluorescent dye. Sulfo-Cy5 amine hydrochloride reacts with electrophilic substances .
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- HY-D2268
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Fluorescent Dye
Amyloid-β
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Neurological Disease
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QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
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- HY-D2268A
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Amyloid-β
Fluorescent Dye
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Neurological Disease
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QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
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- HY-152102
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Fluorescent Dye
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Cancer
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BTCy is a near-infrared (NIR) fluorescence probe with polarity-responsive and cell plasma membrane-targeting properties. BTCy can be used for in vivo imaging of tumor tissue (λex = 561 nm, λem = 600-700 nm) .
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- HY-W248594
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Fluorescent Dye
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Others
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IR 813 tosylate is a near-infrared (NIR) fluorescent dye (λex=815 nm, λem=840 nm) and can be used for visualizing regional lymph nodes in mice .
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- HY-111653
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CycLuc1
1 Publications Verification
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Reactive Oxygen Species
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Others
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CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
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- HY-D1535
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Fluorescent Dye
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Others
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IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice .
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- HY-D1719
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Fluorescent Dye
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Others
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Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging .
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- HY-D1389
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Sulfo-Cyanine5.5 NHS ester tripotassium
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Fluorescent Dye
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Others
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Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
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- HY-W879007
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Fluorescent Dye
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Others
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ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
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- HY-D1063
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Fluorescent Dye
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Cancer
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IR780 is a prototypic NIR heptamethine cyanine agent, with a high molar extinction coefficient. The maximum excitation wavelength of IR780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm. IR780 can be used in cancer PTT/PDT and imaging .
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- HY-D1716
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Fluorescent Dye
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Cancer
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S0456 is a near-infrared (NIR) fluorescent dye that can be used for synthesize Pafolacianine (HY-139579). S0456 binds to the folate receptor (FR). S0456 can be used as a tumor-specific optical imaging agent. The excitation wavelength is 788 nM and emission wavelength is 800 nM .
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- HY-D1568
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Fluorescent Dye
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Others
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Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
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- HY-D1325
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Fluorescent Dye
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Others
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Cyanine5.5 alkyne chloride, a near-infrared (NIR) fluorescent dye, is an alkyne modified Cyanine5.5 (Ex=680 nm, Em=710 nm). Cyanine5.5 alkyne chloride can react with azides for Click Chemistry labeling .
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- HY-149298
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PSMA
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Cancer
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PSMA-IN-2 is an inhibitor of PSMA with a Ki value of 1.07 nM. PSMA-IN-2 displays favorable in vivo NIR imaging (λEM = 1088 nm, λex = 808 nm), and can be used for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice .
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- HY-D1541
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Fluorescent Dye
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Others
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Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.
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- HY-150971
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Pyroptosis
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Cancer
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ICy-Q is a quinone oxidoreductase 1 (NQO-1)-activated near-infrared (NIR) reagent which can react with NQO-1 to release the reduction product ICy-OH. ICy-OH selectively induces pancreatic cancer cell death through the pyroptosis pathway. ICy-Q can be used as an effective tool for rapid and accurate diagnosis of intraoperative pathological sections .
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- HY-D1308
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Fluorescent Dye
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Others
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Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling .
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- HY-155062
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Mitochondrial Metabolism
Reactive Oxygen Species
β-catenin
Fluorescent Dye
PPAR
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Cancer
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IR-251 is a mitochondrion-targeting NIR fluorescent probe. IR-251 targets mitochondria via OATPs and causes mitochondrial damage in tumor cells. IR-251 IR-251 induced ROS overproduction by inhibiting PPARγ, and then inhibiting the β-catenin signaling pathway and downstream protein molecules related to the cell cycle and metastasis. IR-251 inhibits tumor proliferation and metastasis .
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- HY-D1540
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Cy 5.5 amine; Lumiprobe Cy 5.5 amine
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Fluorescent Dye
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Others
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Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
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- HY-D1539
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CY 5.5 azide; Lumiprobe CY 5.5 azide
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Fluorescent Dye
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Others
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Cyanine 5.5 azide (CY 5.5 azide) is a potent fluorescent dye. Cyanine 5.5 azide can label DNA. Cyanine 5.5 azide can be used for NIR live organism imaging. (λex=684 nm, λem=710 nm) . Cyanine 5.5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-142523
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- HY-D1449
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- HY-D2250
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Fluorescent Dye
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Others
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Disulfo-ICG carboxylic acid is a derivative of ICG dye. ICG (Indocyanine Green) is a NIR fluorescent dye .
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- HY-D1744
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Fluorescent Dye
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Others
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ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging.
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- HY-136946
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Fluorescent Dye
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Others
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HITCI is a commercially available, positively charged indocarbocyanine dye. HITCI is used typically as a laser dye in the near infrared (NIR) .
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- HY-D2189
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IRDye 700DX NHS ester
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Fluorescent Dye
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Others
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IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
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- HY-D1873
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Fluorescent Dye
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Others
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800CW acid is a near-infrared (NIR) dye that can be used for protein labeling. 800CW acid can be used for in vivo imaging studies .
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- HY-D1053
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- HY-D1400
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Fluorescent Dye
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Others
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HBTP-H2S (chloride) is a NIR fluorescent probe for in situ bioimaging of endogenous H2S in rice roots under Al 3+ and flooding stresses.
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- HY-P5287
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Integrin
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Cancer
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cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .
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- HY-133852
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Fluorescent Dye
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Others
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FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .
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- HY-P5287A
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Integrin
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Cancer
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cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .
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- HY-103242
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Amyloid-β
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Neurological Disease
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CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM .
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- HY-133852A
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Fluorescent Dye
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Others
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FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging .
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- HY-D1392
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Ag2Te
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Fluorescent Dye
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Others
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Ag2Te QDs (Ag2Te) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .
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- HY-149203A
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Fluorescent Dye
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Others
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MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO -, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
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- HY-W088089
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Fluorescent Dye
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Others
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ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue .
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- HY-155003
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Fluorescent Dye
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Cancer
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TPEQM-DMA is a NIR-II photosensitizer. TPEQM-DMA accumulates in cancerous mitochondria, and inhibits cancer cell growth. TPEQM-DMA has potent type-I phototherapeutic efficacy to overcome the intrinsic pitfalls of PDT in combating hypoxic tumors .
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- HY-D1504
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Fluorescent Dye
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Others
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IR-797 chloride is a near-infrared (NIR) dye. IR 797 has absorption maxima near 700 nm. IR-797 shows some aggregation-induced-emission (AIE) properties. IR-797 shows shows cytotoxic .
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- HY-149765
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Others
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Others
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Bone-1064 is a EuK-based PSMA tetramer bone probe for high-contrast visualization of bone in surrounding tissue. Bone-1064 specifically binds hydroxyapatite in bone tissue and can be used for NIR-II fluorescence imaging in animal models .
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- HY-D1393
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Pb:Ag2Se
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Fluorescent Dye
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Others
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Pb:Ag2Se QDs (Pb:Ag2Se) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .
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- HY-151109
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Fluorescent Dye
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Others
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IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H2O2 in vivo. IR-990 is a powerful diagnosis of agent-induced liver injury (DILI) .
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- HY-D2227
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Autophagy
Apoptosis
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Cancer
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IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .
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- HY-163077
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Reactive Oxygen Species
Apoptosis
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Cancer
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Anticancer agent 175 (complex 1) ia a near-infrared (NIR) luminescent theranostic complex. Anticancer agent 175 induces ROS accumulation, mitochondrial damage, disruption of Bax/Bcl-2 equilibrium, and tumor cell apoptosis in HepG2 cell line .
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- HY-157317
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Apoptosis
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Cancer
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Antitumor agent-126 (Compound II4) is a photoactive (IC50= 0.149) anticancer agent with significant near-infrared fluorescence emission at 650-760 nm. Antitumor agent-126 has antiproliferative activity and can induce apoptosis after laser irradiation. Antitumor agent-126 effectively inhibits tumor growth in mouse xenograft models exposed to 650 nm laser irradiation. Antitumor agent-126 can be used in cancer research .
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- HY-151757
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Fluorescent Dye
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Others
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Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
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- HY-139109
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ADS 780WS
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Fluorescent Dye
Apoptosis
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Others
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IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer .
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- HY-D1324
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Fluorescent Dye
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Others
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Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
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- HY-D1464
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CH1055
1 Publications Verification
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Fluorescent Dye
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Cancer
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CH1055 is a NIR-II fluorophore based on a synthetic 970-Da organic molecule. CH1055 is a rapidly excreted dye (∼90% excreted through the kidneys within 24 h). CH1055 also allows targeted molecular imaging of tumors in vivo when conjugated with anti-EGFR Affibody .
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- HY-D1600
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Fluorescent Dye
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Others
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Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
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- HY-114879
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DDAO
1 Publications Verification
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Fluorescent Dye
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Cancer
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DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases .
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- HY-151753
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Fluorescent Dye
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Others
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Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
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- HY-D1464A
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Fluorescent Dye
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Cancer
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CH1055 triethylamine is a NIR-II fluorophore based on a synthetic 970-Da organic molecule. CH1055 triethylamine is a rapidly excreted dye (∼90% excreted through the kidneys within 24 h). CH1055 triethylamine also allows targeted molecular imaging of tumors in vivo when conjugated with anti-EGFR Affibody .
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- HY-149297
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PSMA
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Cancer
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PSMA-IN-1 (compound 23) is an inhibitor of PSMA with a Ki value of 2.49 nM. PSMA-IN-1 inhibits tumor growth with high selectivity and specificity in PSMA+ xenograft models. PSMA-IN-1 is a NIR probe (λEX: 620 nm; λEM: 670 nm) used for tumor disappearance. PSMA-IN-1 can be used for research on prostate cancer .
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- HY-D2194
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Fluorescent Dye
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Others
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AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
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- HY-149380
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Raf
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Cancer
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Vem-L-Cy5 (compound 3)，modified with the NIR fluorophore cyanine-5 (Cy5)，is a Vemurafenib (HY-12057)-based inhibitor of BRAF. Vem-L-Cy5 targets to BRAF V600E，and also inhibits MEK phosphorylation. Vem-L-Cy5 has cell permeability，and inhibits cell growth of many types of cancer .
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- HY-D1376A
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Fluorescent Dye
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Others
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Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling .
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- HY-D1068
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DBCO-Sulfo-Cy5
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Fluorescent Dye
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Others
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Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-D1583
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DBCO-Cy5; Cyanine5 dibenzocyclooctyne
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Fluorescent Dye
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Others
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Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
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- HY-D1320
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Fluorescent Dye
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Others
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Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) .
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- HY-D1321
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Cyanine5 amine(hydrochloride)
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Fluorescent Dye
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Others
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Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) .
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- HY-151406
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Apoptosis
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Cancer
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hCAIX-IN-13 (Pt2) is an inhibitor of CAIX (arbonic anhydrase IX) with an IC50 value of 6.57 μM. hCAIX-IN-13 inhibits growth of cancer cells and induces cell apoptosis, it can be used for the research of cancer .
|
-
- HY-P5520
-
|
|
Bombesin Receptor
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
-
- HY-D1566
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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-
| Cat. No. |
Product Name |
Type |
-
- HY-D1067
-
|
|
Fluorescent Dyes/Probes
|
|
NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .
|
-
- HY-D1066
-
|
|
Fluorescent Dyes/Probes
|
|
NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. NIR-Thiol dinitrobenzenesulfonate responds to thiol with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-Thiol dinitrobenzenesulfonate is capable of imaging endogenously produced thiol in living cells and mice .
|
-
- HY-D1065
-
|
|
Fluorescent Dyes/Probes
|
|
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
|
-
- HY-D1514
-
-
- HY-151890
-
|
|
Fluorescent Dyes/Probes
|
|
NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .
|
-
- HY-D1500
-
|
|
Fluorescent Dyes/Probes
|
|
Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35) .
|
-
- HY-D1555
-
-
- HY-D2215
-
|
|
Fluorescent Dyes/Probes
|
|
Mito-CCY is a mitochondria-targeted, NIR-absorbing cryptocyanine probe. Mito-CCY displays a high photothermal conversion efficiency, good biological compatibility in vitro, and photoinduced cytotoxicity in HeLa cells .
|
-
- HY-D1394
-
|
AgAuSe
|
Quantum Dots
|
|
AgAuSe QDs (AgAuSe) is a near infrared (NIR) fluorescent quantum dots (QDs), with a bright emission from 820 to 1170 nm. AgAuSe QDs can be used for the research in biomedical imaging and NIR devices .
|
-
- HY-D1375A
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy5 amine hydrochloride is a near-infrared (NIR) amino fluorescent dye. Sulfo-Cy5 amine hydrochloride reacts with electrophilic substances .
|
-
- HY-D2268
-
|
|
Fluorescent Dyes/Probes
|
|
QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
|
-
- HY-D2268A
-
|
|
Fluorescent Dyes/Probes
|
|
QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
|
-
- HY-111653
-
CycLuc1
1 Publications Verification
|
Chromogenic Substrates
|
|
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
|
-
- HY-D1535
-
|
|
Fluorescent Dyes/Probes
|
|
IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice .
|
-
- HY-D1389
-
|
Sulfo-Cyanine5.5 NHS ester tripotassium
|
Fluorescent Dyes/Probes
|
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
|
-
- HY-W879007
-
|
|
Fluorescent Dyes/Probes
|
|
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
|
-
- HY-D1063
-
|
|
Fluorescent Dyes/Probes
|
|
IR780 is a prototypic NIR heptamethine cyanine agent, with a high molar extinction coefficient. The maximum excitation wavelength of IR780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm. IR780 can be used in cancer PTT/PDT and imaging .
|
-
- HY-D1568
-
|
|
Dyes
|
|
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
|
-
- HY-D1325
-
|
|
Dyes
|
|
Cyanine5.5 alkyne chloride, a near-infrared (NIR) fluorescent dye, is an alkyne modified Cyanine5.5 (Ex=680 nm, Em=710 nm). Cyanine5.5 alkyne chloride can react with azides for Click Chemistry labeling .
|
-
- HY-D1541
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.
|
-
- HY-D1308
-
|
|
Dyes
|
|
Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling .
|
-
- HY-D1540
-
|
Cy 5.5 amine; Lumiprobe Cy 5.5 amine
|
Fluorescent Dyes/Probes
|
|
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
|
-
- HY-149203
-
|
|
Fluorescent Dyes/Probes
|
|
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO - (λem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
|
-
- HY-D1539
-
|
CY 5.5 azide; Lumiprobe CY 5.5 azide
|
DNA Stain
|
|
Cyanine 5.5 azide (CY 5.5 azide) is a potent fluorescent dye. Cyanine 5.5 azide can label DNA. Cyanine 5.5 azide can be used for NIR live organism imaging. (λex=684 nm, λem=710 nm) . Cyanine 5.5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D2250
-
|
|
Fluorescent Dyes/Probes
|
|
Disulfo-ICG carboxylic acid is a derivative of ICG dye. ICG (Indocyanine Green) is a NIR fluorescent dye .
|
-
- HY-D1744
-
|
|
Fluorescent Dyes/Probes
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging.
|
-
- HY-D2189
-
|
IRDye 700DX NHS ester
|
Dyes
|
|
IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
|
-
- HY-D1873
-
|
|
Fluorescent Dyes/Probes
|
|
800CW acid is a near-infrared (NIR) dye that can be used for protein labeling. 800CW acid can be used for in vivo imaging studies .
|
-
- HY-D1053
-
|
Sulfo-Cyanine7-N3
|
Fluorescent Dyes/Probes
|
|
CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble NIR dye azide for Click Chemistry.
|
-
- HY-133852
-
|
|
Fluorescent Dyes/Probes
|
|
FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .
|
-
- HY-149835
-
|
|
Fluorescent Dyes/Probes
|
|
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .
|
-
- HY-D1392
-
|
Ag2Te
|
Quantum Dots
|
|
Ag2Te QDs (Ag2Te) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .
|
-
- HY-W088089
-
|
|
Fluorescent Dyes/Probes
|
|
ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue .
|
-
- HY-D1504
-
|
|
Dyes
|
|
IR-797 chloride is a near-infrared (NIR) dye. IR 797 has absorption maxima near 700 nm. IR-797 shows some aggregation-induced-emission (AIE) properties. IR-797 shows shows cytotoxic .
|
-
- HY-D1393
-
|
Pb:Ag2Se
|
Quantum Dots
|
|
Pb:Ag2Se QDs (Pb:Ag2Se) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .
|
-
- HY-D2227
-
|
|
Fluorescent Dyes/Probes
|
|
IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .
|
-
- HY-151757
-
|
|
Fluorescent Dyes/Probes
|
|
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
|
-
- HY-D1324
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
|
-
- HY-D1600
-
|
|
Dyes
|
|
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
|
-
- HY-114879
-
DDAO
1 Publications Verification
|
Fluorescent Dyes/Probes
|
|
DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases .
|
-
- HY-151753
-
|
|
Fluorescent Dyes/Probes
|
|
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
|
-
- HY-D2194
-
|
|
Fluorescent Dyes/Probes
|
|
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
|
-
- HY-D1376A
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling .
|
-
- HY-D1068
-
|
DBCO-Sulfo-Cy5
|
Fluorescent Dyes/Probes
|
|
Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D1583
-
|
DBCO-Cy5; Cyanine5 dibenzocyclooctyne
|
Fluorescent Dyes/Probes
|
|
Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
|
-
- HY-D1320
-
|
|
Dyes
|
|
Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) .
|
-
- HY-D1321
-
|
Cyanine5 amine(hydrochloride)
|
Dyes
|
|
Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) .
|
-
- HY-D1566
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
| Cat. No. |
Product Name |
Type |
-
- HY-139109
-
|
ADS 780WS
|
Biochemical Assay Reagents
|
|
IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5287A
-
|
|
Integrin
|
Cancer
|
|
cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .
|
-
- HY-P5287
-
|
|
Integrin
|
Cancer
|
|
cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .
|
-
- HY-P5520
-
|
|
Bombesin Receptor
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-D1539
-
|
CY 5.5 azide; Lumiprobe CY 5.5 azide
|
|
Azide
|
|
Cyanine 5.5 azide (CY 5.5 azide) is a potent fluorescent dye. Cyanine 5.5 azide can label DNA. Cyanine 5.5 azide can be used for NIR live organism imaging. (λex=684 nm, λem=710 nm) . Cyanine 5.5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D1053
-
-
- HY-W879007
-
|
|
|
Azide
|
|
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
|
-
- HY-D1325
-
|
|
|
Alkynes
|
|
Cyanine5.5 alkyne chloride, a near-infrared (NIR) fluorescent dye, is an alkyne modified Cyanine5.5 (Ex=680 nm, Em=710 nm). Cyanine5.5 alkyne chloride can react with azides for Click Chemistry labeling .
|
-
- HY-D1308
-
|
|
|
Azide
|
|
Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling .
|
-
- HY-151757
-
|
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
|
-
- HY-151753
-
|
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
|
-
- HY-D1068
-
|
DBCO-Sulfo-Cy5
|
|
DBCO
Labeling and Fluorescence Imaging
|
|
Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D1320
-
|
|
|
Azide
|
|
Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) .
|
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