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Cat. No.: HY-D1449

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IR-1061

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

IR-1061 is a near infrared fluorescent organic dye for in vivo bimodal imaging.

For research use only. We do not sell to patients.

Purity: 80.0%
CAS No.: 155614-01-0
Formula: C₄₄H₃₄BClF₄S₂
Molecular Weight:749.13

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

IR-1061 Chemical Structure

CAS No.: 155614-01-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IR-1061 is a near infrared fluorescent organic dye for in vivo bimodal imaging^[1]^[2].

In Vitro

The emission peak of IR-1061 is approximately at 1100 nm, the main absorption peak is at 1064 nm, and there is a slight shoulder peak at 890 nm^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

IR-1061 exhibits excellent performance in in vivo imaging experiments on mice. Bimodal imaging is performed by a single injection of the PLP-D probe containing IR-1061. In OTN-NIR imaging, signals can be observed 30 seconds after injection. Blood vessels and the liver are visualized first, and the signals remains stable within 300 seconds after injection. Most of the signals accumulates in the liver and spleen 150 minutes later. In MRI, imaging startes 30 minutes after injection, and signal changes in regions such as the liver and bladder can be observed^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 155614-01-0
Appearance Solid
Molecular Weight 749.13
Formula C₄₄H₃₄BClF₄S₂
Color Brown to black
SMILES

[F-][B+3]([F-])([F-])[F-].ClC1=C(/C=C/C2=CC(C3=CC=CC=C3)=[S+]C(C4=CC=CC=C4)=C2)CCC/C1=C/C=C5C=C(C6=CC=CC=C6)SC(C7=CC=CC=C7)=C/5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (1)

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Adv Funct Mater

2026 Jan 26.

Solvent & Solubility

In Vitro:

DMSO : 5 mg/mL (6.67 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

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Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.3349 mL

6.6744 mL

13.3488 mL

5 mM

0.2670 mL

1.3349 mL

2.6698 mL

10 mM

---

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Thi Kim Dung Doan, et al. The influence of Gd-DOTA conjugating ratios to PLGA-PEG micelles encapsulated IR-1061 on bimodal over-1000 nm near-infrared fluorescence and magnetic resonance imaging. Biomater Sci. 2022 Mar 2;10(5):1217-1230. [Content Brief]

[2]. Doan TKD, et al. The effect of Gd-DOTA locations within PLGA-b-PEG micelle encapsulated IR-1061 on bimodal over-1000 nm near-infrared fluorescence and magnetic resonance imaging. Biomater Sci. 2022 Oct 25;10(21):6244-6257. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.3349 mL	6.6744 mL	13.3488 mL	33.3720 mL
DMSO	5 mM	0.2670 mL	1.3349 mL	2.6698 mL	6.6744 mL

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