Cy5-DBCO
Based on 3 publication(s) in Google Scholar
Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 98.93%
- CAS No.: 1564286-24-3
- Formula: C52H56N4O11S3
- Molecular Weight:1009.22
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Cy5-DBCO
More
Biological Activity
Red fluorescent dye
Cy5-DBCO (DBCO-Sulfo-Cy5) reacts with azides via a copper-free “click chemistry” reaction and forms a stable triazole and does not need Cu-catalyst or elevated temperatures.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 1564286-24-3
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Appearance Solid
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Molecular Weight 1009.22
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Formula C52H56N4O11S3
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Color Blue to black
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SMILES
O=S(CCC[N+]1=C(/C=C/C=C/C=C(N(CCCCCC(NCCC(N2C3=CC=CC=C3C#CC4=CC=CC=C4C2)=O)=O)C5=CC=C(C=C65)S(=O)(O)=O)/C6(C)C)C(C)(C)C7=CC(S(=O)(O)=O)=CC=C17)([O-])=O
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Synonyms
DBCO-Sulfo-Cy5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (3)
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Journal Impact Factor
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Most Recent
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Nat Commun
Observation of structural switch in nascent SAM-VI riboswitch during transcription at single-nucleotide and single-molecule resolution. [Abstract]2023 Apr 22;14(1):2320. PMID: 37087479 -
Acta Biomater
Redox-responsive dendritic copolymer-drug conjugates enhance therapeutic mitophagy through coordinated microtubule destabilization for synergistic triple-negative breast cancer therapy. [Abstract]2025 Aug:202:248-261. PMID: 40555336 -
Solvent & Solubility
DMSO : 62.5 mg/mL (61.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 10 mg/mL (9.91 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (255 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 0.9909 mL | 4.9543 mL | 9.9086 mL | 24.7716 mL |
| 5 mM | 0.1982 mL | 0.9909 mL | 1.9817 mL | 4.9543 mL | |
| DMSO | 10 mM | 0.0991 mL | 0.4954 mL | 0.9909 mL | 2.4772 mL |
| 15 mM | 0.0661 mL | 0.3303 mL | 0.6606 mL | 1.6514 mL | |
| 20 mM | 0.0495 mL | 0.2477 mL | 0.4954 mL | 1.2386 mL | |
| 25 mM | 0.0396 mL | 0.1982 mL | 0.3963 mL | 0.9909 mL | |
| 30 mM | 0.0330 mL | 0.1651 mL | 0.3303 mL | 0.8257 mL | |
| 40 mM | 0.0248 mL | 0.1239 mL | 0.2477 mL | 0.6193 mL | |
| 50 mM | 0.0198 mL | 0.0991 mL | 0.1982 mL | 0.4954 mL | |
| 60 mM | 0.0165 mL | 0.0826 mL | 0.1651 mL | 0.4129 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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