GB-6
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects.
For research use only. We do not sell to patients.
- CAS No.: 2413262-74-3
- Formula: C32H45N11O8
- Molecular Weight:711.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
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RDC Peptide |
Chemical Information
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CAS No. 2413262-74-3
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Molecular Weight 711.77
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Formula C32H45N11O8
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Sequence
Gln-{Htp}-{β-Ala}-{Nva}-Gly-His-NH2
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Sequence Shortening
Q-{Htp}-{β-Ala}-{Nva}-GH-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GB-6 Related Classifications
HY-P5520 Related Classifications
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