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Results for "

cancer and nervous system diseases

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Amyloid-β (4) Apoptosis (4) Aryl Hydrocarbon Receptor (1) Autophagy (4) Bacterial (5) Biochemical Assay Reagents (2) CDK (2) Cholinesterase (ChE) (2) Dengue Virus (1) Endogenous Metabolite (5) Environmental Pollutants (1) Epigenetic Reader Domain (1) FAK (1) Fungal (2) GABA Receptor (1) GPR35 (1) HBV (1) HDAC (1) HIV (2) iGluR (2) Influenza Virus (2) MMP (2) MOFs (1) mTOR (1) NF-κB (2) NO Synthase (1) PARP (2) PI3K (1) PKA (2) Reference Standards (5) RET (1) STAT (1) TNF Receptor (2) Tyrosinase (1)
By Research Areas:	Cancer (21) Cardiovascular Disease (7) Infection (6) Inflammation/Immunology (8) Metabolic Disease (7) Neurological Disease (22)

By Targets:

Akt (1)

Amyloid-β (4)

Apoptosis (4)

Aryl Hydrocarbon Receptor (1)

Autophagy (4)

Bacterial (5)

Biochemical Assay Reagents (2)

CDK (2)

Cholinesterase (ChE) (2)

Dengue Virus (1)

Endogenous Metabolite (5)

Environmental Pollutants (1)

Epigenetic Reader Domain (1)

FAK (1)

Fungal (2)

GABA Receptor (1)

GPR35 (1)

HBV (1)

HDAC (1)

HIV (2)

iGluR (2)

Influenza Virus (2)

MMP (2)

MOFs (1)

mTOR (1)

NF-κB (2)

NO Synthase (1)

PARP (2)

PI3K (1)

PKA (2)

Reference Standards (5)

RET (1)

STAT (1)

TNF Receptor (2)

Tyrosinase (1)

By Research Areas:

Cancer (21)

Cardiovascular Disease (7)

Infection (6)

Inflammation/Immunology (8)

Metabolic Disease (7)

Neurological Disease (22)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Natural
Products

Targets Recommended: Complement System BCRP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0528

Linarin 4 Publications Verification Buddleoside; Linarine	TNF Receptor Cholinesterase (ChE) PKA Apoptosis Bacterial HIV Influenza Virus	Infection Neurological Disease Inflammation/Immunology Cancer
Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer .

HY-N2581

Phytic acid sodium salt 1 Publications Verification myo-Inositol, hexakisdihydrogen phosphate sodium salt; Inositol hexaphosphate sodium salt	MOFs Endogenous Metabolite Amyloid-β Autophagy	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) sodium salt is an orally active compound. Phytic acid sodium salt can be derived from the seeds of legumes. Phytic acid sodium salt is a [PO4] ³- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid sodium salt attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid sodium salt can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research .

HY-16468

Squalamine 1 Publications Verification MSI-1256; ENT-01 free acid	Bacterial HBV FAK Dengue Virus	Infection Neurological Disease Cancer
Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ^,s disease mouse models .

HY-N3002

α-Arbutin 4-Hydroxyphenyl α-D-glucopyranoside	Tyrosinase	Neurological Disease Metabolic Disease Cancer
α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes .

HY-N0814

Phytic acid (50% w/w in water) 1 Publications Verification Inositol hexaphosphate; SNF472 free acid	Endogenous Metabolite Amyloid-β Autophagy	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) is an orally active compound. Phytic acid can be derived from the seeds of legumes. Phytic acid is a [PO4] ³- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research .

HY-34431

Purine 7H-Imidazo(4,5-d)pyrimidine	Endogenous Metabolite PARP	Neurological Disease Metabolic Disease Cancer
Purine is an endogenous metabolite. Purine bases are the building blocks of the nucleic acids. Purine inhibits the activation of PARP. Purine protects against oxidant-induced cell injury. Purine can be used in the research of cancer and nervous system diseases .

HY-W015236

H-Gly-Gly-Gly-OH Triglycine	Biochemical Assay Reagents	Others
H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

HY-B0900

Anethole 2 Publications Verification Anise camphor; p-Propenylanisole; Isoestragole	Environmental Pollutants Apoptosis NF-κB Fungal Bacterial MMP	Infection Neurological Disease Inflammation/Immunology Cancer
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .

HY-129692

Withanone 1 Publications Verification	iGluR	Neurological Disease Cancer
Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .

HY-132806

Alogabat RG-7816; RO-7017773	GABA Receptor	Neurological Disease
Alogabat is a positive allosteric modulator (PAM) and agonist (K_i <100 nM) of the GABAA α5 receptor, targeting the α5β3γ2 subunit with a Ki of 8.7 nM. Alogabat increases the expression level of α5β3γ2 in oocytes (1.97-fold). GABAA has been implicated in cognitive impairment associated with central nervous system (CNS) disorders, brain cancer (including brain tumors such as medulloblastoma), and can be used in the study of mild cognitive impairment (MCI), amnestic MCI (aMCI), age-associated memory impairment (AAMI), age-related cognitive decline (ARCD), dementia, Alzheimer's disease (AD), prodromal AD, post-traumatic stress disorder (PTSD), schizophrenia, bipolar disorder, amyotrophic lateral sclerosis (ALS), cognitive impairment associated with cancer treatment, mental retardation, Parkinson's disease (PD), autism spectrum disorder, fragile X, Rett syndrome, obsessive-compulsive behavior, and substance addiction .

HY-N2000

Bellidifolin 1 Publications Verification	STAT PI3K mTOR Akt	Neurological Disease Inflammation/Immunology Cancer
Bellidifolin is an orally active compound with antiproliferative, anti-inflammatory and antioxidant properties. Bellidifolin modulates key signaling pathways including STAT3, PI3K-Akt, mTOR and BRD4, and inhibits the viral protein R (Vpr). Bellidifolin induces cell cycle arrest and apoptosis, exerts significant antifibrotic effects, and protects the heart, liver and nervous system. Bellidifolin is applicable to the research of various diseases such as lung cancer, non-alcoholic fatty liver disease, myocardial hypertrophy and ischemic cranial nerve injury .

HY-N2580

Zinc Phytate 1 Publications Verification	Endogenous Metabolite Amyloid-β Autophagy	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Zinc Phytate (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) is an orally active compound. Zinc Phytate can be derived from the seeds of legumes. Zinc Phytate is a [PO4] ³- storage depot and precursor for other inositol phosphates and pyrophosphates. Zinc Phytate attenuates Aβ oligomers and upregulates autophagy protein. Zinc Phytate can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research .

HY-169575

PARP1-IN-36	PARP	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
PARP1-IN-36 (compound 11) is a 4-carboxamido-isoindolinone derivative and a selective PARP-1 inhibitor with a K_d < 0.01 μM. PARP1-IN-36 can be utilized in cancer, cardiovascular diseases, nervous system injury and inflammation research .

HY-N0528R

Linarin (Standard) Buddleoside (Standard); Linarine (Standard)	TNF Receptor Reference Standards Cholinesterase (ChE) PKA Apoptosis Bacterial HIV Influenza Virus	Infection Neurological Disease Inflammation/Immunology Cancer
Linarin (Standard) is the analytical standard of Linarin. This product is intended for research and analytical applications. Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer.

HY-E70684

CDK5/p25NCK Recombinant Human Active Protein Kinase	CDK	Neurological Disease Cancer
CDK5 can be mapped to chromosome 7q36 and its expression is upregulated by the transcription factors Fos and CREB through the MEK/ERK pathway and by δFosB. CDK5 plays a vital role in the central nervous system but has functions in other cell types. CDK5 has recently been implicated in diseases, including the development and progression of cancer and neurodegenerative diseases. CDK5/p25NCK Recombinant Human Active Protein Kinase is an ortholog of CDK5 .

HY-E70685

CDK5/p35NCK Recombinant Human Active Protein Kinase	CDK	Neurological Disease Cancer
CDK5 can be mapped to chromosome 7q36 and its expression is upregulated by the transcription factors Fos and CREB through the MEK/ERK pathway and by δFosB. CDK5 plays a vital role in the central nervous system but has functions in other cell types. CDK5 has recently been implicated in diseases, including the development and progression of cancer and neurodegenerative diseases. CDK5/p35NCK Recombinant Human Active Protein Kinase is an ortholog of CDK5 .

HY-B0900R

Anethole (Standard) Anise camphor (Standard); p-Propenylanisole (Standard); Isoestragole (Standard)	Apoptosis Fungal Bacterial MMP NF-κB Reference Standards	Infection Neurological Disease Inflammation/Immunology Cancer
Anethole (Standard) is the analytical standard of Anethole. This product is intended for research and analytical applications. Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .

HY-131728

GPR35 agonist 3	GPR35	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
GPR35 agonist 3 is a synthetic GPR35 agonist with an EC₅₀value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system .

HY-143546

RET-IN-9	RET	Cancer
RET-IN-9 is a potent inhibitor of RET. RET kinase is a single-pass transmembrane receptor tyrosine kinase that plays an important role in the development of the kidney and enteric nervous system, and the maintenance of homeostasis in the nervous, endocrine, hematopoietic, and male reproductive systems. RET-IN-9 has the potential for the research of RET-related disease including non-small cell lung cancer and medullary thyroid cancer (extracted from patent WO2021115457A1, compound 29) .

HY-160446

BET-IN-24	Epigenetic Reader Domain	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Bet-in-24 (example 2) is a bromodomain and extra-terminal (BET) inhibitor. BET-IN-24 can be used in the study of virology, heart failure, inflammation, central nervous system (CNS) diseases and many cancers

HY-163806

NT376	HDAC	Neurological Disease Cancer
NT376 is a high potency and selectivity inhibitor of class-IIa Histone deacetylases (HDAC) with an IC₅₀ value of 32 nM, similar to NT160 (HY-149285) (IC₅₀= 46 nM) in HT-29 cells. NT376 is proming for research of various cancers and in the diseases of the central nervous system (CNS) such as Alzheimer’s and Huntington’s diseases .

HY-W015236R

H-Gly-Gly-Gly-OH (Standard) Triglycine (Standard)	Biochemical Assay Reagents Reference Standards	Others
H-Gly-Gly-Gly-OH (Standard) is the analytical standard of H-Gly-Gly-Gly-OH. This product is intended for research and analytical applications. H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

HY-118700AR

2-Iminobiotin hydrobromide (Standard) Guanidinobiotin hydrobromide (Standard)	Reference Standards NO Synthase	Neurological Disease
H-Gly-Gly-Gly-OH (Standard) is the analytical standard of H-Gly-Gly-Gly-OH. This product is intended for research and analytical applications. H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

HY-B0311D

Carbidopa hydrochloride (S)-(-)-Carbidopa hydrochloride	Aryl Hydrocarbon Receptor	Cancer
Carbidopa hydrochloride ((S)-(-)-Carbidopa hydrochloride) is a drug used to inhibit Parkinson's disease, which has the activity of inhibiting the peripheral metabolism of levodopa. Carbidopa hydrochloride can increase the proportion of peripheral levodopa penetrating the blood-brain barrier, thereby enhancing its effect on the central nervous system. Carbidopa hydrochloride has also been found to be an aryl hydrocarbon receptor (AhR) ligand with anticancer activity, which can inhibit the growth of pancreatic cancer cells and tumors. The selective AhR regulation properties of carbidopa hydrochloride provide potential prospects for its clinical application .

HY-129692R

Withanone (Standard)	Reference Standards iGluR	Neurological Disease Cancer
Withanone (Standard) is the analytical standard of Withanone (HY-129692). This product is intended for research and analytical applications. Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .

HY-181448

Phytic acid hexalithium Inositol hexaphosphate hexalithium; SNF472 hexalithium	Endogenous Metabolite Amyloid-β Autophagy	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Phytic acid (Inositol hexaphosphate hexalithium) hexalithium is an orally active compound. Phytic acid hexalithium can be derived from the seeds of legumes. Phytic acid is a [PO4] ³- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid hexalithium attenuates Aβ oligomers and upregulates Autophagy protein. Phytic acid hexalithium can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research .

Cat. No.	Product Name

HY-L072

Exosomes Compound Library	53 compounds
Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining. The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 53 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

Exosomes Compound Library

53 compounds

Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.

The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 53 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

Cat. No.	Product Name	Type

HY-W015236

H-Gly-Gly-Gly-OH Triglycine	Biochemical Assay Reagents
H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

H-Gly-Gly-Gly-OH

Triglycine

Biochemical Assay Reagents

H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

HY-W015236R

H-Gly-Gly-Gly-OH (Standard) Triglycine (Standard)	Biochemical Assay Reagents
H-Gly-Gly-Gly-OH (Standard) is the analytical standard of H-Gly-Gly-Gly-OH. This product is intended for research and analytical applications. H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

H-Gly-Gly-Gly-OH (Standard)

Triglycine (Standard)

Biochemical Assay Reagents

H-Gly-Gly-Gly-OH (Standard) is the analytical standard of H-Gly-Gly-Gly-OH. This product is intended for research and analytical applications. H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

Linarin 4 Publications Verification Buddleoside; Linarine	Flavonoids Flavones Labiatae Erythrina poeppigiana Plants Source Classification	TNF Receptor Cholinesterase (ChE) PKA Apoptosis Bacterial HIV Influenza Virus
Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer .

Phytic acid sodium salt 1 Publications Verification myo-Inositol, hexakisdihydrogen phosphate sodium salt; Inositol hexaphosphate sodium salt	Structural Classification Natural Products Zea mays L. Classification of Application Fields Gramineae Other Diseases Plants Disease Research Fields Source Classification	MOFs Endogenous Metabolite Amyloid-β Autophagy
Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) sodium salt is an orally active compound. Phytic acid sodium salt can be derived from the seeds of legumes. Phytic acid sodium salt is a [PO4] ³- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid sodium salt attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid sodium salt can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research .

Squalamine 1 Publications Verification MSI-1256; ENT-01 free acid	Infection Triterpenes Animals Classification of Application Fields Terpenoids Marine natural products Other marine organisms Disease Research Fields Cancer	Bacterial HBV FAK Dengue Virus
Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ^,s disease mouse models .

α-Arbutin 4-Hydroxyphenyl α-D-glucopyranoside	Monophenols Classification of Application Fields Phenols Metabolic Disease Cosmetic Research Ericaceae Plants Disease Research Fields Source Classification	Tyrosinase
α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes .

Phytic acid (50% w/w in water) 1 Publications Verification Inositol hexaphosphate; SNF472 free acid	Structural Classification other families Neurological Disease Classification of Application Fields Food Preservation Research Ketones, Aldehydes, Acids Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification Agricultural Research	Endogenous Metabolite Amyloid-β Autophagy
Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) is an orally active compound. Phytic acid can be derived from the seeds of legumes. Phytic acid is a [PO4] ³- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research .

Purine 7H-Imidazo(4,5-d)pyrimidine	Natural Products Microorganisms Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite PARP
Purine is an endogenous metabolite. Purine bases are the building blocks of the nucleic acids. Purine inhibits the activation of PARP. Purine protects against oxidant-induced cell injury. Purine can be used in the research of cancer and nervous system diseases .

Anethole 2 Publications Verification Anise camphor; p-Propenylanisole; Isoestragole	Structural Classification Classification of Application Fields Simple Phenylpropanols Leguminosae Phenylpropanoids Umbelliferae Plants Vernonia Schreb. Glycyrrhiza uralensis Fisch. Disease Research Fields Source Classification Cancer	Environmental Pollutants Apoptosis NF-κB Fungal Bacterial MMP
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .

Withanone 1 Publications Verification	Withania somnifera Solanaceae Plants Steroids Source Classification	iGluR
Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .

Bellidifolin 1 Publications Verification	Infection Structural Classification Xanthones Classification of Application Fields Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Gentianaceae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	STAT PI3K mTOR Akt
Bellidifolin is an orally active compound with antiproliferative, anti-inflammatory and antioxidant properties. Bellidifolin modulates key signaling pathways including STAT3, PI3K-Akt, mTOR and BRD4, and inhibits the viral protein R (Vpr). Bellidifolin induces cell cycle arrest and apoptosis, exerts significant antifibrotic effects, and protects the heart, liver and nervous system. Bellidifolin is applicable to the research of various diseases such as lung cancer, non-alcoholic fatty liver disease, myocardial hypertrophy and ischemic cranial nerve injury .

Zinc Phytate 1 Publications Verification	Natural Products other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Endogenous Metabolite Amyloid-β Autophagy
Zinc Phytate (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) is an orally active compound. Zinc Phytate can be derived from the seeds of legumes. Zinc Phytate is a [PO4] ³- storage depot and precursor for other inositol phosphates and pyrophosphates. Zinc Phytate attenuates Aβ oligomers and upregulates autophagy protein. Zinc Phytate can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research .

Linarin (Standard) Buddleoside (Standard); Linarine (Standard)	Structural Classification Flavonoids Flavones Labiatae Erythrina poeppigiana Plants Source Classification	TNF Receptor Reference Standards Cholinesterase (ChE) PKA Apoptosis Bacterial HIV Influenza Virus
Linarin (Standard) is the analytical standard of Linarin. This product is intended for research and analytical applications. Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer.

Anethole (Standard) Anise camphor (Standard); p-Propenylanisole (Standard); Isoestragole (Standard)	Structural Classification Simple Phenylpropanols Leguminosae Phenylpropanoids Umbelliferae Plants Vernonia Schreb. Glycyrrhiza uralensis Fisch. Source Classification	Apoptosis Fungal Bacterial MMP NF-κB Reference Standards
Anethole (Standard) is the analytical standard of Anethole. This product is intended for research and analytical applications. Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .

Withanone (Standard)	Withania somnifera Solanaceae Plants Steroids Source Classification	Reference Standards iGluR
Withanone (Standard) is the analytical standard of Withanone (HY-129692). This product is intended for research and analytical applications. Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .

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