2. Immunology/Inflammation
  3. Aryl Hydrocarbon Receptor
  4. Carbidopa hydrochloride

Carbidopa hydrochloride  (Synonyms: (S)-(-)-Carbidopa hydrochloride)

Cat. No.: HY-B0311D
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Carbidopa hydrochloride ((S)-(-)-Carbidopa hydrochloride) is a drug used to inhibit Parkinson's disease, which has the activity of inhibiting the peripheral metabolism of levodopa. Carbidopa hydrochloride can increase the proportion of peripheral levodopa penetrating the blood-brain barrier, thereby enhancing its effect on the central nervous system. Carbidopa hydrochloride has also been found to be an aryl hydrocarbon receptor (AhR) ligand with anticancer activity, which can inhibit the growth of pancreatic cancer cells and tumors. The selective AhR regulation properties of carbidopa hydrochloride provide potential prospects for its clinical application.

For research use only. We do not sell to patients.

CAS No. : 65132-60-7

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Carbidopa hydrochloride Related Antibodies

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Carbidopa hydrochloride

Cell Proliferation/Viability Assay

    Carbidopa hydrochloride purchased from MedChemExpress. Usage Cited in: SSRN. 2026 Mar 6.

    Carbidopa treatment 455 significantly attenuated the growth-promoting effects of aspartame-treated A. muciniphila supernatants 456 on MC38 cells

    Carbidopa hydrochloride purchased from MedChemExpress. Usage Cited in: SSRN. 2026 Mar 6.

    Carbidopa effectively blocked the proliferative effects of 457 exogenous 5-HTP treatment.

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    Description

    Carbidopa hydrochloride ((S)-(-)-Carbidopa hydrochloride) is a drug used to inhibit Parkinson's disease, which has the activity of inhibiting the peripheral metabolism of levodopa. Carbidopa hydrochloride can increase the proportion of peripheral levodopa penetrating the blood-brain barrier, thereby enhancing its effect on the central nervous system. Carbidopa hydrochloride has also been found to be an aryl hydrocarbon receptor (AhR) ligand with anticancer activity, which can inhibit the growth of pancreatic cancer cells and tumors. The selective AhR regulation properties of carbidopa hydrochloride provide potential prospects for its clinical application[1].

    Molecular Weight

    262.69

    Formula

    C10H15ClN2O4
    CAS No.
    SMILES

    OC(C=C1C[C@@](NN)(C)C(O)=O)=C(C=C1)O.Cl
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Carbidopa hydrochloride Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Carbidopa65132-60-7(S)-(-)-CarbidopaAryl Hydrocarbon ReceptorAhRpancreaticcancerParkinson'sdiseaseperipheralInhibitorinhibitorinhibit

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