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  4. H-Gly-Gly-Gly-OH

H-Gly-Gly-Gly-OH  (Synonyms: Triglycine)

Cat. No.: HY-W015236 Purity: 99.70%
COA
SDS
Handling Instructions Technical Support

H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

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H-Gly-Gly-Gly-OH

H-Gly-Gly-Gly-OH 화학구조

CAS No. : 556-33-2

사이즈 가격 재고 수량
1 g 해외재고보유
5 g 해외재고보유
10 g   견적 받기  
50 g   견적 받기  

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of H-Gly-Gly-Gly-OH:

H-Gly-Gly-Gly-OH Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • 순도&문서

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제품 설명

H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

Cellular Effect
Cell Line Type Value Description References
CHO IC50
1400 μM
Compound: Gly-Gly-Gly
TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 25000 uM) in PEPT1-expressing CHO cells
TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 25000 uM) in PEPT1-expressing CHO cells
[PMID: 8956326]
MDCK EC50
0.58 mM
Compound: 26
Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
[PMID: 16759105]
MDCK IC50
1.07 mM
Compound: 26
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
[PMID: 16759105]
In Vitro

H-Gly-Gly-Gly-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

H-Gly-Gly-Gly-OH Related Antibodies
분자량

189.17

화학식

C6H11N3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CNC(CNC(CN)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

RT, protect from light

In solvent -80°C 1 year
-20°C 6 months
용액&용해도
In Vitro: 

H2O : 50 mg/mL (264.31 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2863 mL 26.4313 mL 52.8625 mL
5 mM 1.0573 mL 5.2863 mL 10.5725 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.70%

SDS (393 KB)

COA (242 KB) HNMR (215 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.2863 mL 26.4313 mL 52.8625 mL 132.1563 mL
5 mM 1.0573 mL 5.2863 mL 10.5725 mL 26.4313 mL
10 mM 0.5286 mL 2.6431 mL 5.2863 mL 13.2156 mL
15 mM 0.3524 mL 1.7621 mL 3.5242 mL 8.8104 mL
20 mM 0.2643 mL 1.3216 mL 2.6431 mL 6.6078 mL
25 mM 0.2115 mL 1.0573 mL 2.1145 mL 5.2863 mL
30 mM 0.1762 mL 0.8810 mL 1.7621 mL 4.4052 mL
40 mM 0.1322 mL 0.6608 mL 1.3216 mL 3.3039 mL
50 mM 0.1057 mL 0.5286 mL 1.0573 mL 2.6431 mL
60 mM 0.0881 mL 0.4405 mL 0.8810 mL 2.2026 mL
80 mM 0.0661 mL 0.3304 mL 0.6608 mL 1.6520 mL
100 mM 0.0529 mL 0.2643 mL 0.5286 mL 1.3216 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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H-Gly-Gly-Gly-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H-Gly-Gly-Gly-OH556-33-2TriglycineBiochemical Assay Reagentsbiochemical assayreagentInhibitorinhibitorinhibit

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상품명:
H-Gly-Gly-Gly-OH
Cat. No.:
HY-W015236
수량:
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SAFETY DATA SHEET (SDS)

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