Leu-Leu-OH
Based on 1 Customer Validation
Leu-Leu-OH (L-Leucyl-L-leucine), a Leu derivative, is a neutral dipeptide that can be used to study the functionality of dileucine motifs.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.10%
- CAS 番号: 3303-31-9
- 分子式: C12H24N2O3
- 分子量:244.33
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | EC50 |
0.08 mM
Compound: 44
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Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
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[PMID: 16759105] |
| MDCK | IC50 |
0.17 mM
Compound: 44
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Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
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[PMID: 16759105] |
In hamster jejunum, Leu-Leu-OH (L-Leucyl-L-leucine) could inhibit mediated uptake of intact glycylsarcosine completely, but glycylsarcosine could not cause complete inhibition of mediated uptake of intact Leu-Leu-OH[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 3303-31-9
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性状 Solid
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分子量 244.33
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分子式 C12H24N2O3
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Color White to off-white
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別名
L-Leucyl-L-leucine
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配列
Leu-Leu
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シーケンスの短縮
LL
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
H2O : 16.28 mg/mL (66.63 mM; ultrasonic and adjust pH to 10 with 1 M NaOH)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.0928 mL | 20.4641 mL | 40.9283 mL | 102.3206 mL |
| 5 mM | 0.8186 mL | 4.0928 mL | 8.1857 mL | 20.4641 mL | |
| 10 mM | 0.4093 mL | 2.0464 mL | 4.0928 mL | 10.2321 mL | |
| 15 mM | 0.2729 mL | 1.3643 mL | 2.7286 mL | 6.8214 mL | |
| 20 mM | 0.2046 mL | 1.0232 mL | 2.0464 mL | 5.1160 mL | |
| 25 mM | 0.1637 mL | 0.8186 mL | 1.6371 mL | 4.0928 mL | |
| 30 mM | 0.1364 mL | 0.6821 mL | 1.3643 mL | 3.4107 mL | |
| 40 mM | 0.1023 mL | 0.5116 mL | 1.0232 mL | 2.5580 mL | |
| 50 mM | 0.0819 mL | 0.4093 mL | 0.8186 mL | 2.0464 mL | |
| 60 mM | 0.0682 mL | 0.3411 mL | 0.6821 mL | 1.7053 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Leu-Leu-OH 関連分類
HY-W008642 関連分類
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