Glycyl-L-leucine
Based on 1 Customer Validation
Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.
For research use only. We do not sell to patients.
- Purity: 99.49%
- CAS No.: 869-19-2
- Formula: C8H16N2O3
- Molecular Weight:188.22
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | EC50 |
0.17 mM
Compound: 30
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Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
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[PMID: 16759105] |
| MDCK | IC50 |
0.07 mM
Compound: 30
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Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
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[PMID: 16759105] |
Chemical Information
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CAS No. 869-19-2
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Appearance Solid
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Molecular Weight 188.22
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Formula C8H16N2O3
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Color White to off-white
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SMILES
CC(C)C[C@@H](C(O)=O)NC(CN)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 25 mg/mL (132.82 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (265.65 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.3129 mL | 26.5647 mL | 53.1293 mL | 132.8233 mL |
| 5 mM | 1.0626 mL | 5.3129 mL | 10.6259 mL | 26.5647 mL | |
| 10 mM | 0.5313 mL | 2.6565 mL | 5.3129 mL | 13.2823 mL | |
| 15 mM | 0.3542 mL | 1.7710 mL | 3.5420 mL | 8.8549 mL | |
| 20 mM | 0.2656 mL | 1.3282 mL | 2.6565 mL | 6.6412 mL | |
| 25 mM | 0.2125 mL | 1.0626 mL | 2.1252 mL | 5.3129 mL | |
| 30 mM | 0.1771 mL | 0.8855 mL | 1.7710 mL | 4.4274 mL | |
| 40 mM | 0.1328 mL | 0.6641 mL | 1.3282 mL | 3.3206 mL | |
| 50 mM | 0.1063 mL | 0.5313 mL | 1.0626 mL | 2.6565 mL | |
| 60 mM | 0.0885 mL | 0.4427 mL | 0.8855 mL | 2.2137 mL | |
| 80 mM | 0.0664 mL | 0.3321 mL | 0.6641 mL | 1.6603 mL | |
| 100 mM | 0.0531 mL | 0.2656 mL | 0.5313 mL | 1.3282 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Glycyl-L-leucine Related Classifications
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