2. Others
  3. Amino Acid Derivatives
  4. H-Gly-Sar-OH

H-Gly-Sar-OH  (Synonyms: Glycylsarcosine; Gly-Sar)

Cat. No.: HY-W010276 Purity: 99.87%
COA
SDS
Handling Instructions Technical Support

H-Gly-Sar-OH is a Glycine (HY-Y0966) derivative.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

H-Gly-Sar-OH

H-Gly-Sar-OH Chemical Structure

CAS No. : 29816-01-1

Size Price Stock Quantity
500 mg In-stock
1 g In-stock
5 g In-stock
10 g   Get quote  
50 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

H-Gly-Sar-OH Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE H-Gly-Sar-OH

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

H-Gly-Sar-OH is a Glycine (HY-Y0966) derivative[1].

Cellular Effect
Cell Line Type Value Description References
HEK293 EC50
123 μM
Compound: 93131
Substrate uptake by the Peptide Transporter 2 (PEPT2, SLC15A2) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC15A2 cells (PubChem AID: 1794819)
Substrate uptake by the Peptide Transporter 2 (PEPT2, SLC15A2) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC15A2 cells (PubChem AID: 1794819)
10.5281/zenodo.7360449
HEK293 EC50
39 μM
Compound: 93131
Substrate uptake by the Peptide Transporter 2 (PEPT2, SLC15A2) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC15A2 cells (PubChem AID: 1794819)
Substrate uptake by the Peptide Transporter 2 (PEPT2, SLC15A2) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC15A2 cells (PubChem AID: 1794819)
10.5281/zenodo.7360449
MDCK EC50
0.54 mM
Compound: 37
Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
[PMID: 16759105]
MDCK IC50
1.16 mM
Compound: 37
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
[PMID: 16759105]
In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

H-Gly-Sar-OH Related Antibodies
Molecular Weight

146.14

Formula

C5H10N2O3
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Gly-{Sar}
Sequence Shortening

G-{Sar}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 41.67 mg/mL (285.14 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8428 mL 34.2138 mL 68.4275 mL
5 mM 1.3686 mL 6.8428 mL 13.6855 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.87%

SDS (393 KB)

COA (243 KB) HNMR (225 KB) RP-HPLC (276 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.8428 mL 34.2138 mL 68.4275 mL 171.0688 mL
5 mM 1.3686 mL 6.8428 mL 13.6855 mL 34.2138 mL
10 mM 0.6843 mL 3.4214 mL 6.8428 mL 17.1069 mL
15 mM 0.4562 mL 2.2809 mL 4.5618 mL 11.4046 mL
20 mM 0.3421 mL 1.7107 mL 3.4214 mL 8.5534 mL
25 mM 0.2737 mL 1.3686 mL 2.7371 mL 6.8428 mL
30 mM 0.2281 mL 1.1405 mL 2.2809 mL 5.7023 mL
40 mM 0.1711 mL 0.8553 mL 1.7107 mL 4.2767 mL
50 mM 0.1369 mL 0.6843 mL 1.3686 mL 3.4214 mL
60 mM 0.1140 mL 0.5702 mL 1.1405 mL 2.8511 mL
80 mM 0.0855 mL 0.4277 mL 0.8553 mL 2.1384 mL
100 mM 0.0684 mL 0.3421 mL 0.6843 mL 1.7107 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

H-Gly-Sar-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H-Gly-Sar-OH29816-01-1Glycylsarcosine Gly-SarAmino Acid DerivativesInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
H-Gly-Sar-OH
Cat. No.:
HY-W010276
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (393 KB) Français - FR (393 KB) Deutsch - DE (393 KB) Norwegian - NO (393 KB) Español - ES (393 KB) Swedish - SV (393 KB) Italian - IT (393 KB) Korean - KR (393 KB) Portuguese - PT (393 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.