29816-01-1
29816-01-1
Chemical Structure
H-Gly-Sar-OH
Synonym(s): Glycylsarcosine; Gly-Sar
- CAS No.: 29816-01-1
- Formula:C5H10N2O3
- Molecular Weight:146.14
IUPAC Name: N-glycyl-N-methylglycine
InChIKey: VYAMLSCELQQRAE-UHFFFAOYSA-N
SMILES: CN(C(CN)=O)CC(O)=O
Biological Activity: H-Gly-Sar-OH (Glycylsarcosine; Gly-Sar) is a dipeptide formed by the condensation of glycine and sarcosine. H-Gly-Sar-OH can be used to study the function and transport mechanism of PEPT1[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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H-Gly-Sar-OH | 99.87% | H-Gly-Sar-OH (Glycylsarcosine; Gly-Sar) is a dipeptide formed by the condensation of glycine and sarcosine. H-Gly-Sar-OH can be used to study the function and transport mechanism of PEPT1. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-P4296H-Gly-Sar-Sar-OH -
Similarity Score 0.81
HY-W007872N-Methyliminodiacetic acid -
Similarity Score 0.81
HY-D0889RGlycylglycine (Standard) -
Similarity Score 0.79
HY-W010388Creatine -
Similarity Score 0.79
HY-W010388SCreatine-13C -
Similarity Score 0.79
HY-W040074Glycylglycine hydrochloride hydrate -
Similarity Score 0.78
HY-W017462Creatine monohydrate -
Similarity Score 0.78
HY-W017462S1Creatine-13C monohydrate -
Similarity Score 0.77
HY-W141910Glycyl-L-alanine -
Explore the MedChemAI to find more analogs
References
- [1]. Paizs B, et al. Experimental and theoretical investigation of the main fragmentation pathways of protonated H-Gly-Gly-Sar-OH and H-Gly-Sar-Sar-OH. Journal of the American Society for Mass Spectrometry. 2003 Dec;14(12):1454-69.
- [2]. Nabulsi NB, et al. [11C]Glycylsarcosine: synthesis and in vivo evaluation as a PET tracer of PepT2 transporter function in kidney of PepT2 null and wild-type mice. Bioorg Med Chem. 2005 Apr 15;13(8):2993-3001.
- [3]. Ganapathy V, et al. Characteristics of glycylsarcosine transport in rabbit intestinal brush-border membrane vesicles. J Biol Chem. 1984 Jul 25;259(14):8954-9.
- [4]. Payne JW, et al. Conformational limitations of glycylsarcosine as a prototypic substrate for peptide transporters. Biochimica et biophysica acta. 2001 Sep 03;1514(1):65-75.
- [5]. von Linde T, et al. Rapid and Sensitive Quantification of Intracellular Glycyl-Sarcosine for Semi-High-Throughput Screening for Inhibitors of PEPT-1. Pharmaceutics. 2021 Jul 3;13(7):1019. [Content Brief]
