H-Gly-Sar-Sar-OH
H-Gly-Sar-Sar-OH is an orally active tripeptide. H-Gly-Sar-Sar-OH is transported through PepT1 within Caco-2 cells. H-Gly Sar Sar OH has potential applications in material transportation.
For research use only. We do not sell to patients.
- CAS No.: 57836-11-0
- Formula: C8H15N3O4
- Molecular Weight:217.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
H-Gly-Sar-Sar-OH (10 mg/kg; p.o.; single dose) shows stability in spontaneously hypertensive rats (SHRs)[3].
Pharmacokinetic (PK) parameters of H-Gly-Sar-Sar-OH in SHRs[3]
| Week old | Cmax (nmol/mL, plasma) | Tmax (min) | AUC0-90 min (nmol•min/mL, plasma) | T1/2 (min) |
| 8 | 4.6±0.6 | 30 | 258.0±32.1 | 75 |
| 40 | 10.7±1.5 | 30 | 621.0±86.3 | 83 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 57836-11-0
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Molecular Weight 217.22
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Formula C8H15N3O4
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Sequence
H-Gly-Sar-Sar-OH
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Sequence Shortening
G-{Sar}-{Sar}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hong SM, et al. Structural Design of Oligopeptides for Intestinal Transport Model. J Agric Food Chem. 2016 Mar 16;64(10):2072-9. [Content Brief]
[2]. Minami H, et al. Oligopeptides: mechanism of renal clearance depends on molecular structure. Am J Physiol. 1992 Jul;263(1 Pt 2):F109-15. [Content Brief]
[3]. Hanh VT, et al. Effect of Aging on the Absorption of Small Peptides in Spontaneously Hypertensive Rats. J Agric Food Chem. 2017 Jul 26;65(29):5935-5943. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
H-Gly-Sar-Sar-OH Related Classifications
HY-P4296 Related Classifications
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