2. Anti-infection
  3. Bacterial Influenza Virus Antibiotic Orthopoxvirus
  4. Rifampicin

Rifampicin  (Synonyms: Rifampin; Rifamycin AMP)

Cat. No.: HY-B0272 Pureté: 98.23%
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Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity.

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CAS No. : 13292-46-1

Size Prix Stock Quantité
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
500 mg En stock
1 g En stock
5 g En stock
10 g   Obtenir un devis  
50 g   Obtenir un devis  

* Veuillez sélectionner la quantité avant d'ajouter des articles.

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Based on 45 publication(s) in Google Scholar

Other Forms of Rifampicin:

Rifampicin Related Antibodies

Top Publications Citing Use of Products

45 Publications Citing Use of MCE Rifampicin

Bio/Physico-chemical Assay
Microbiological Assay
Cell Imaging/Staining
Flow Cytometry
WB

    Rifampicin purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2025 Apr 9:757:151624.  [Abstract]

    Ability of different concentrations compounds or drugs (GM, Gentamicin, Sterile; AMG 837; RORγt 13; RIF; 4, 16 μg/mL) to clear B. melitensis TZ in RAW264.7 cells at 24 h. Cells appear blue; B. melitensis TZ appear green.

    Rifampicin purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2022 Jun;43(6):1605-1615.  [Abstract]

    The antibacterial activity of compound B2 and H3 against M. smegmatis. The TBA-7371 and rifampin (7 d) were used as positive controls.

    Rifampicin purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2020 Jul 21;7(17):2001374.  [Abstract]

    Rapid killing kinetics of the combination (>99.9% killing in 10 min). pEt_20: 0.5× MIC (7.8 µg/mL), rifampicin: 0.5× MIC (0.50 µg/mL). Limit of detection: 50 CFU/mL.

    Rifampicin purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2020 Jul 21;7(17):2001374.  [Abstract]

    Fluorescence intensity analysis of intracellular ROS probe CellRox Green in A. baumannii BAA‐1709 (≈107 CFU/mL) after treatment with rifampicin (0.50 µg/mL), pEt_20 , and their combination over various periods of time (0-30 min).

    Rifampicin purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2020 Jul 21;7(17):2001374.  [Abstract]

    Flow cytometric analysis of intracellular ROS levels after 10 min treatment with rifampicin (0.5 µg/mL), pEt_20, or their combination.

    Rifampicin purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2019 Mar 15:56:175-182.  [Abstract]

    Representative Western blots for P-gp、BCRP、MRP2 in LS-180 treated with six active compounds in liquorice. C: control, P-1: Rifampicin, P-2: Bosentan, S-1: Liquiritin, S-2: Liquiritigenin, S-3: Isoliquiritin, S-4: Isoliquiritigenin, S-5: Glycyrrhetinic acid, S-6: Licochalcone A.

    Rifampicin purchased from MedChemExpress. Usage Cited in: Onco Targets Ther. 2018 Sep 17:11:5885-5894.  [Abstract]

    MHCC97-H cells are treated with the indicated concentrations of Rifampicin for 48 hours. Then, cells are harvested for Western blot analysis.

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    Description

    Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity.

    Cellular Effect
    Cell Line Type Value Description References
    A549 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human A549 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human A549 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    A549 GI50
    >100 6
    Compound: RP
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    A549 GI50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    A549 GI50
    >100 6
    Compound: Rifampicin
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    A549 GI50
    >121.51 2
    Compound: RP
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    		10.1039/C6MD00278A
    A549 GI50
    > 100 6
    Compound: RP
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    A549 GI50
    > 100 6
    Compound: RP
    Growth inhibition of human A549 cells by MTT assay
    Growth inhibition of human A549 cells by MTT assay
    		[PMID: 30910461]
    A549 GI50
    >100 6
    Compound: RIF
    Cytotoxicity against human A549 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human A549 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    A549 GI50
    >100 6
    Compound: RP
    Growth inhibition of human A549 cells by MTT assay
    Growth inhibition of human A549 cells by MTT assay
    		[PMID: 30910461]
    A549 GI50
    > 100 6
    Compound: Rifampicin
    Growth inhibition of human A549 cells by MTT assay
    Growth inhibition of human A549 cells by MTT assay
    		[PMID: 28411559]
    A549 GI50
    > 121.51 2
    Compound: RP
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    		10.1039/C6MD00278A
    A549 GI50
    >100 6
    Compound: Rifampicin
    Growth inhibition of human A549 cells by MTT assay
    Growth inhibition of human A549 cells by MTT assay
    		[PMID: 28411559]
    B-cell IC50
    96 3
    Compound: Rifampin
    Antiproliferative activity against Theileria parva-induced proliferation of bovine B lymphocyte assessed as inhibition of [3H]thymidine uptake after 48 hrs
    Antiproliferative activity against Theileria parva-induced proliferation of bovine B lymphocyte assessed as inhibition of [3H]thymidine uptake after 48 hrs
    		[PMID: 19075064]
    B-cell IC50
    96 3
    Compound: Rifampin
    Antiproliferative activity against Theileria parva-induced proliferation of bovine B lymphocyte assessed as inhibition of [3H]thymidine uptake after 48 hrs
    Antiproliferative activity against Theileria parva-induced proliferation of bovine B lymphocyte assessed as inhibition of [3H]thymidine uptake after 48 hrs
    		[PMID: 19075064]
    CHO CC50
    512 3
    Compound: RIF
    Cytotoxicity against CHO cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against CHO cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31525660]
    CHO CC50
    512 3
    Compound: RIF
    Cytotoxicity against CHO cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against CHO cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31525660]
    HCT-116 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human HCT116 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human HCT116 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    HCT-116 CC50
    >100 6
    Compound: Rifampicin
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		[PMID: 27301367]
    HCT-116 GI50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    HCT-116 GI50
    >100 6
    Compound: Rifampicin
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    HCT-116 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		[PMID: 27914801]
    HCT-116 GI50
    >100 6
    Compound: RIF
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		[PMID: 27914801]
    A549 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human A549 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human A549 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    HCT-116 CC50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		[PMID: 27301367]
    HCT-116 GI50
    >121.51 2
    Compound: RP
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		10.1039/C6MD00278A
    A549 GI50
    > 100 6
    Compound: RP
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    HCT-116 GI50
    >100 6
    Compound: RIF
    Cytotoxicity against human HCT116 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human HCT116 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    HCT-116 GI50
    > 121.51 2
    Compound: RP
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		10.1039/C6MD00278A
    HEK293 CC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay
    		[PMID: 30392371]
    HEK293 CC50
    >100 3
    Compound: Rifampicin
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay
    		[PMID: 30392371]
    A549 GI50
    > 100 6
    Compound: RP
    Growth inhibition of human A549 cells by MTT assay
    Growth inhibition of human A549 cells by MTT assay
    		[PMID: 30910461]
    A549 GI50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    HEK293 IC50
    0.3 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrate
    		[PMID: 22587986]
    HEK293 EC50
    1.1 3
    Compound: Rifampicin
    Agonist activity at human PXR transfected in HEK293 cells after 24 hrs by luciferase reporter gene assay
    Agonist activity at human PXR transfected in HEK293 cells after 24 hrs by luciferase reporter gene assay
    		[PMID: 26905831]
    A549 GI50
    > 100 6
    Compound: Rifampicin
    Growth inhibition of human A549 cells by MTT assay
    Growth inhibition of human A549 cells by MTT assay
    		[PMID: 28411559]
    HEK293 EC50
    1.1 3
    Compound: Rifampicin
    Agonist activity at human PXR transfected in HEK293 cells after 24 hrs by luciferase reporter gene assay
    Agonist activity at human PXR transfected in HEK293 cells after 24 hrs by luciferase reporter gene assay
    		[PMID: 26905831]
    HEK293 IC50
    1.2 3
    Compound: Rifampicin
    Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation counting
    Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation counting
    		[PMID: 22541068]
    HEK293 IC50
    1.2 3
    Compound: Rifampicin
    Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation counting
    Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation counting
    		[PMID: 22541068]
    HEK293 IC50
    1.5 3
    Compound: Rifampicin
    Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillation counting
    Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillation counting
    		[PMID: 22541068]
    A549 GI50
    > 121.51 2
    Compound: RP
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    		10.1039/C6MD00278A
    HEK293 IC50
    65 3
    Compound: Rifampicin
    Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation counting
    Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation counting
    		[PMID: 22541068]
    HEK293 IC50
    1.5 3
    Compound: Rifampicin
    Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillation counting
    Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillation counting
    		[PMID: 22541068]
    HEK293 IC50
    2.2 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrate
    		[PMID: 22587986]
    HEK293 IC50
    0.3 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrate
    		[PMID: 22587986]
    B-cell IC50
    96 3
    Compound: Rifampin
    Antiproliferative activity against Theileria parva-induced proliferation of bovine B lymphocyte assessed as inhibition of [3H]thymidine uptake after 48 hrs
    Antiproliferative activity against Theileria parva-induced proliferation of bovine B lymphocyte assessed as inhibition of [3H]thymidine uptake after 48 hrs
    		[PMID: 19075064]
    HEK293 IC50
    2.3 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estrone-3-sulfate substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estrone-3-sulfate substrate
    		[PMID: 22587986]
    HEK293 IC50
    2.3 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estrone-3-sulfate substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estrone-3-sulfate substrate
    		[PMID: 22587986]
    CHO CC50
    512 3
    Compound: RIF
    Cytotoxicity against CHO cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against CHO cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31525660]
    HEK293 IC50
    2.2 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrate
    		[PMID: 22587986]
    HEK293 IC50
    65 3
    Compound: Rifampicin
    Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation counting
    Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation counting
    		[PMID: 22541068]
    HeLa GI50
    > 100 6
    Compound: RP
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    HeLa CC50
    >100 6
    Compound: Rifampicin
    Cytotoxicity against human HeLa cells by MTT assay
    Cytotoxicity against human HeLa cells by MTT assay
    		[PMID: 27301367]
    HeLa GI50
    > 100 6
    Compound: RP
    Growth inhibition of human HeLa cells by MTT assay
    Growth inhibition of human HeLa cells by MTT assay
    		[PMID: 30910461]
    HeLa GI50
    >100 6
    Compound: RP
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    HeLa GI50
    > 100 6
    Compound: Rifampicin
    Growth inhibition of human HeLa cells by MTT assay
    Growth inhibition of human HeLa cells by MTT assay
    		[PMID: 28411559]
    HeLa GI50
    >100 6
    Compound: RP
    Growth inhibition of human HeLa cells by MTT assay
    Growth inhibition of human HeLa cells by MTT assay
    		[PMID: 30910461]
    HeLa CC50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human HeLa cells by MTT assay
    Cytotoxicity against human HeLa cells by MTT assay
    		[PMID: 27301367]
    HeLa GI50
    >100 6
    Compound: Rifampicin
    Growth inhibition of human HeLa cells by MTT assay
    Growth inhibition of human HeLa cells by MTT assay
    		[PMID: 28411559]
    HeLa IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    HeLa IC50
    270 6
    Compound: rifampin
    Antiproliferative effect against HeLa cells after 48 hrs
    Antiproliferative effect against HeLa cells after 48 hrs
    		[PMID: 17088489]
    HCT-116 CC50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		[PMID: 27301367]
    HeLa IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    HeLa IC50
    >20 3
    Compound: RIF
    Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    Hepatocyte EC50
    1.3 3
    Compound: Rifampicin
    Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS method
    Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS method
    		[PMID: 22815312]
    HeLa IC50
    270 6
    Compound: rifampin
    Antiproliferative effect against HeLa cells after 48 hrs
    Antiproliferative effect against HeLa cells after 48 hrs
    		[PMID: 17088489]
    HCT-116 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human HCT116 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human HCT116 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    Hepatocyte IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against primary human hepatocytes assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against primary human hepatocytes assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    Hepatocyte EC50
    0.98 3
    Compound: Rifampicin
    Induction of CYP2B6 mRNA expression in human donor hepatocytes after 48 hrs by real-time PCR method
    Induction of CYP2B6 mRNA expression in human donor hepatocytes after 48 hrs by real-time PCR method
    		[PMID: 22815312]
    HCT-116 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		[PMID: 27914801]
    Hepatocyte EC50
    0.98 3
    Compound: Rifampicin
    Induction of CYP2B6 mRNA expression in human donor hepatocytes after 48 hrs by real-time PCR method
    Induction of CYP2B6 mRNA expression in human donor hepatocytes after 48 hrs by real-time PCR method
    		[PMID: 22815312]
    Hepatocyte IC50
    >20 3
    Compound: RIF
    Cytotoxicity against primary human hepatocytes assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against primary human hepatocytes assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    HCT-116 GI50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    Hepatocyte EC50
    1.3 3
    Compound: Rifampicin
    Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS method
    Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS method
    		[PMID: 22815312]
    HepG2 CC50
    175.9 6
    Compound: RIF
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 33940463]
    HCT-116 GI50
    > 121.51 2
    Compound: RP
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    		10.1039/C6MD00278A
    HepG2 EC50
    0.19 3
    Compound: Rifampicin
    Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assay
    Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assay
    		[PMID: 27145071]
    HepG2 EC50
    3.5 3
    Compound: Rifampicin
    Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
    Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
    		[PMID: 20966043]
    HEK293 CC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay
    		[PMID: 30392371]
    HepG2 IC50
    145.33 3
    Compound: Rifampicin
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
    		[PMID: 32249118]
    HepG2 EC50
    3.2 3
    Compound: Rifampicin
    Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
    Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
    		[PMID: 20966043]
    HEK293 EC50
    1.1 3
    Compound: Rifampicin
    Agonist activity at human PXR transfected in HEK293 cells after 24 hrs by luciferase reporter gene assay
    Agonist activity at human PXR transfected in HEK293 cells after 24 hrs by luciferase reporter gene assay
    		[PMID: 26905831]
    HepG2 CC50
    175.9 6
    Compound: RIF
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 33940463]
    HepG2 EC50
    0.19 3
    Compound: Rifampicin
    Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assay
    Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assay
    		[PMID: 27145071]
    HepG2 IC50
    22.2 3
    Compound: 75
    Antimalarial activity against liver stages of Plasmodium yoelii 17XNL expressing GFP infected in human HepG2 cells transfected with CD81 assessed as growth inhibition of hepatic parasite after 40 hrs by flow cytometry
    Antimalarial activity against liver stages of Plasmodium yoelii 17XNL expressing GFP infected in human HepG2 cells transfected with CD81 assessed as growth inhibition of hepatic parasite after 40 hrs by flow cytometry
    		[PMID: 22122518]
    HepG2 IC50
    22.2 3
    Compound: 75
    Antimalarial activity against liver stages of Plasmodium yoelii 17XNL expressing GFP infected in human HepG2 cells transfected with CD81 assessed as growth inhibition of hepatic parasite after 40 hrs by flow cytometry
    Antimalarial activity against liver stages of Plasmodium yoelii 17XNL expressing GFP infected in human HepG2 cells transfected with CD81 assessed as growth inhibition of hepatic parasite after 40 hrs by flow cytometry
    		[PMID: 22122518]
    HEK293 IC50
    0.3 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrate
    		[PMID: 22587986]
    HepG2 EC50
    3.2 3
    Compound: Rifampicin
    Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
    Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
    		[PMID: 20966043]
    HepG2 IC50
    145.33 3
    Compound: Rifampicin
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
    		[PMID: 32249118]
    HepG2 EC50
    3.5 3
    Compound: Rifampicin
    Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
    Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
    		[PMID: 20966043]
    Huh-7 IC50
    >20 3
    Compound: RIF
    Cytotoxicity against human HuH7 cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against human HuH7 cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    HEK293 IC50
    1.2 3
    Compound: Rifampicin
    Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation counting
    Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation counting
    		[PMID: 22541068]
    HEK293 IC50
    1.5 3
    Compound: Rifampicin
    Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillation counting
    Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillation counting
    		[PMID: 22541068]
    Huh-7 IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against human HuH7 cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against human HuH7 cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    J774.A1 CC50
    207.03 6
    Compound: rifampin
    Cytotoxicity against mouse J774A1 cells after 24 to 72 hrs by MTT assay
    Cytotoxicity against mouse J774A1 cells after 24 to 72 hrs by MTT assay
    		[PMID: 20934344]
    HEK293 IC50
    2.2 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrate
    		[PMID: 22587986]
    Huh-7 IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against human HuH7 cells assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against human HuH7 cells assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    J774.A1 IC50
    >64 6
    Compound: RFP
    Cytotoxicity against mouse J774.A1 cells after 48 hrs by MTT assay
    Cytotoxicity against mouse J774.A1 cells after 48 hrs by MTT assay
    		[PMID: 36150342]
    J774.A1 IC50
    > 100 3
    Compound: RIF
    Cytotoxicity against mouse J774A1 cells assessed as cell viability after 24 hrs by Trypan blue exclusion assay
    Cytotoxicity against mouse J774A1 cells assessed as cell viability after 24 hrs by Trypan blue exclusion assay
    		[PMID: 24611928]
    J774.A1 IC50
    >100 3
    Compound: RIF
    Cytotoxicity against mouse J774A1 cells assessed as cell viability after 24 hrs by Trypan blue exclusion assay
    Cytotoxicity against mouse J774A1 cells assessed as cell viability after 24 hrs by Trypan blue exclusion assay
    		[PMID: 24611928]
    HEK293 IC50
    2.3 3
    Compound: Rifampicin
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estrone-3-sulfate substrate
    Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estrone-3-sulfate substrate
    		[PMID: 22587986]
    J774.A1 IC50
    > 64 6
    Compound: RFP
    Cytotoxicity against mouse J774.A1 cells after 48 hrs by MTT assay
    Cytotoxicity against mouse J774.A1 cells after 48 hrs by MTT assay
    		[PMID: 36150342]
    HEK293 IC50
    65 3
    Compound: Rifampicin
    Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation counting
    Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation counting
    		[PMID: 22541068]
    Macrophage IC50
    >100 3
    Compound: Rifampicin
    Cytotoxicity against mouse bone marrow derived macrophage assessed as growth inhibition after 48 hrs by MTS assay
    Cytotoxicity against mouse bone marrow derived macrophage assessed as growth inhibition after 48 hrs by MTS assay
    		[PMID: 23454512]
    J774.A1 CC50
    207.03 6
    Compound: rifampin
    Cytotoxicity against mouse J774A1 cells after 24 to 72 hrs by MTT assay
    Cytotoxicity against mouse J774A1 cells after 24 to 72 hrs by MTT assay
    		[PMID: 20934344]
    MCF7 GI50
    >100 6
    Compound: Rifampicin
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    MCF7 GI50
    >100 6
    Compound: RIF
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    		[PMID: 27914801]
    Macrophage IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against mouse bone marrow derived macrophage assessed as growth inhibition after 48 hrs by MTS assay
    Cytotoxicity against mouse bone marrow derived macrophage assessed as growth inhibition after 48 hrs by MTS assay
    		[PMID: 23454512]
    MCF7 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human MCF7 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human MCF7 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    MCF7 GI50
    >121.51 2
    Compound: RP
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    		10.1039/C6MD00278A
    MCF7 GI50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    MCF7 GI50
    >100 6
    Compound: RIF
    Cytotoxicity against human MCF7 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human MCF7 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    MCF7 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    		[PMID: 27914801]
    MDCK-II IC50
    >20 3
    Compound: RIF
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    MCF7 GI50
    > 121.51 2
    Compound: RP
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    		10.1039/C6MD00278A
    MG-63 IC50
    240 6
    Compound: rifampin
    Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs
    Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs
    		[PMID: 17088489]
    MDCK-II IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    MRC5 IC50
    >100 3
    Compound: Rifampicin
    Cytotoxicity against human MRC5 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    Cytotoxicity against human MRC5 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    		[PMID: 26213786]
    MDCK-II IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    Osteoblast IC50
    130 6
    Compound: rifampin
    Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs
    Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs
    		[PMID: 17088489]
    MG-63 IC50
    240 6
    Compound: rifampin
    Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs
    Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs
    		[PMID: 17088489]
    PANC-1 CC50
    >100 6
    Compound: Rifampicin
    Cytotoxicity against human PANC1 cells by MTT assay
    Cytotoxicity against human PANC1 cells by MTT assay
    		[PMID: 27301367]
    PANC-1 GI50
    >100 6
    Compound: RP
    Cytotoxicity against human PANC1 cells after 48 hrs by MTT assay
    Cytotoxicity against human PANC1 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    MRC5 IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against human MRC5 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    Cytotoxicity against human MRC5 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    		[PMID: 26213786]
    PANC-1 GI50
    >100 6
    Compound: RP
    Growth inhibition of human PANC1 cells by MTT assay
    Growth inhibition of human PANC1 cells by MTT assay
    		[PMID: 30910461]
    Osteoblast IC50
    130 6
    Compound: rifampin
    Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs
    Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs
    		[PMID: 17088489]
    PANC-1 GI50
    >100 6
    Compound: Rifampicin
    Growth inhibition of human PANC1 cells by MTT assay
    Growth inhibition of human PANC1 cells by MTT assay
    		[PMID: 28411559]
    PANC-1 GI50
    > 100 6
    Compound: RP
    Cytotoxicity against human PANC1 cells after 48 hrs by MTT assay
    Cytotoxicity against human PANC1 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    PANC-1 GI50
    > 100 6
    Compound: RP
    Growth inhibition of human PANC1 cells by MTT assay
    Growth inhibition of human PANC1 cells by MTT assay
    		[PMID: 30910461]
    PBMC IC50
    62.92 6
    Compound: RIF
    Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay
    Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay
    		[PMID: 32977201]
    PANC-1 GI50
    > 100 6
    Compound: Rifampicin
    Growth inhibition of human PANC1 cells by MTT assay
    Growth inhibition of human PANC1 cells by MTT assay
    		[PMID: 28411559]
    RAW264.7 CC50
    24 3
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells
    Cytotoxicity against mouse RAW264.7 cells
    		[PMID: 33071055]
    HeLa CC50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human HeLa cells by MTT assay
    Cytotoxicity against human HeLa cells by MTT assay
    		[PMID: 27301367]
    PANC-1 CC50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human PANC1 cells by MTT assay
    Cytotoxicity against human PANC1 cells by MTT assay
    		[PMID: 27301367]
    RAW264.7 CC50
    80.39 6
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 33940463]
    PBMC IC50
    62.92 6
    Compound: RIF
    Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay
    Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay
    		[PMID: 32977201]
    RAW264.7 GI50
    700 6
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells
    Cytotoxicity against mouse RAW264.7 cells
    		[PMID: 25921267]
    RAW264.7 GI50
    850 3
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells assessed as growth inhibition after 48 hrs by trypan blue assay
    Cytotoxicity against mouse RAW264.7 cells assessed as growth inhibition after 48 hrs by trypan blue assay
    		10.1039/C3MD00251A
    RAW264.7 CC50
    80.39 6
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 33940463]
    RAW264.7 GI50
    850 3
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells assessed as growth inhibition after 48 hrs by trypan blue assay
    Cytotoxicity against mouse RAW264.7 cells assessed as growth inhibition after 48 hrs by trypan blue assay
    		10.1039/C3MD00251A
    THP-1 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human THP1 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human THP1 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    HeLa GI50
    > 100 6
    Compound: RP
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    HeLa GI50
    > 100 6
    Compound: RP
    Growth inhibition of human HeLa cells by MTT assay
    Growth inhibition of human HeLa cells by MTT assay
    		[PMID: 30910461]
    THP-1 GI50
    > 100 6
    Compound: RP
    Cytotoxicity against human THP1 cells after 48 hrs by MTT assay
    Cytotoxicity against human THP1 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    THP-1 CC50
    >100 6
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells by MTT assay
    Cytotoxicity against human THP1 cells by MTT assay
    		[PMID: 27301367]
    HeLa GI50
    > 100 6
    Compound: Rifampicin
    Growth inhibition of human HeLa cells by MTT assay
    Growth inhibition of human HeLa cells by MTT assay
    		[PMID: 28411559]
    THP-1 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human THP1 cells by MTT assay
    Cytotoxicity against human THP1 cells by MTT assay
    		[PMID: 27914801]
    THP-1 GI50
    >100 6
    Compound: RP
    Cytotoxicity against human THP1 cells after 48 hrs by MTT assay
    Cytotoxicity against human THP1 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    THP-1 CC50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells by MTT assay
    Cytotoxicity against human THP1 cells by MTT assay
    		[PMID: 27301367]
    THP-1 GI50
    0.14 6
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human THP1 cells assessed as growth inhibition by MTT assay
    		[PMID: 28103537]
    HeLa IC50
    270 6
    Compound: rifampin
    Antiproliferative effect against HeLa cells after 48 hrs
    Antiproliferative effect against HeLa cells after 48 hrs
    		[PMID: 17088489]
    THP-1 IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    		[PMID: 26213786]
    THP-1 GI50
    >100 6
    Compound: RIF
    Cytotoxicity against human THP1 cells by MTT assay
    Cytotoxicity against human THP1 cells by MTT assay
    		[PMID: 27914801]
    THP-1 IC50
    0.0018 6
    Compound: Rifampicin
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive dormant phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive dormant phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    		[PMID: 26299346]
    THP-1 GI50
    >100 6
    Compound: RIF
    Cytotoxicity against human THP1 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human THP1 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    HeLa IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    HeLa IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    THP-1 IC50
    0.0021 6
    Compound: Rifampicin
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive active phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive active phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    		[PMID: 26299346]
    THP-1 IC50
    0.0021 6
    Compound: Rifampicin
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive active phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive active phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    		[PMID: 26299346]
    THP-1 IC50
    0.0018 6
    Compound: Rifampicin
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive dormant phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive dormant phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    		[PMID: 26299346]
    THP-1 GI50
    0.14 6
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human THP1 cells assessed as growth inhibition by MTT assay
    		[PMID: 28103537]
    Vero IC50
    > 10 6
    Compound: RIP
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell viability after 96 hr by MTT assay
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell viability after 96 hr by MTT assay
    		10.1007/s00044-012-0074-2
    THP-1 IC50
    >100 3
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    		[PMID: 26213786]
    Vero IC50
    > 100 6
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS-PMS assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS-PMS assay
    		[PMID: 24087924]
    Vero CC50
    >50 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiterGlo assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiterGlo assay
    		[PMID: 22691154]
    Vero IC50
    > 100 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20233660]
    Vero CC50
    180 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assat
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assat
    		[PMID: 21146257]
    Vero IC50
    > 100 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19058970]
    Vero CC50
    512 3
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 30296686]
    HepG2 CC50
    175.9 6
    Compound: RIF
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 33940463]
    Vero IC50
    > 100 6
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells measured after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    Cytotoxicity against African green monkey Vero cells measured after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    		[PMID: 30891129]
    Vero CC50
    7.8 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 29407980]
    HepG2 EC50
    0.19 3
    Compound: Rifampicin
    Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assay
    Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assay
    		[PMID: 27145071]
    Vero CC50
    >150 6
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 26498570]
    Vero IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 24 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 24 hrs by MTS assay
    		[PMID: 23454512]
    Vero CC50
    >500 6
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 23062712]
    Vero IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTS assay
    		[PMID: 27426865]
    HepG2 EC50
    3.2 3
    Compound: Rifampicin
    Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
    Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
    		[PMID: 20966043]
    HepG2 EC50
    3.5 3
    Compound: Rifampicin
    Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
    Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
    		[PMID: 20966043]
    Vero IC50
    > 100 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells by MTS assay
    Cytotoxicity against African green monkey Vero cells by MTS assay
    		[PMID: 26748697]
    Vero CC50
    >75.94 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20615698]
    HepG2 IC50
    145.33 3
    Compound: Rifampicin
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
    		[PMID: 32249118]
    Vero IC50
    > 100 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS/PMS assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS/PMS assay
    		[PMID: 29259747]
    Vero CC50
    512 3
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as decrease in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as decrease in cell viability after 72 hrs by MTT assay
    		[PMID: 30992202]
    HepG2 IC50
    22.2 3
    Compound: 75
    Antimalarial activity against liver stages of Plasmodium yoelii 17XNL expressing GFP infected in human HepG2 cells transfected with CD81 assessed as growth inhibition of hepatic parasite after 40 hrs by flow cytometry
    Antimalarial activity against liver stages of Plasmodium yoelii 17XNL expressing GFP infected in human HepG2 cells transfected with CD81 assessed as growth inhibition of hepatic parasite after 40 hrs by flow cytometry
    		[PMID: 22122518]
    Vero IC50
    > 100 3
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells at < 10 uM after 3 days
    Cytotoxicity against african green monkey Vero cells at < 10 uM after 3 days
    		[PMID: 22850215]
    Vero CC50
    500 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28646656]
    Vero CC50
    > 128 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells incubated for 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells incubated for 72 hrs by MTT assay
    		[PMID: 31352245]
    Vero CC50
    500 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28720502]
    HepG2 IC50
    > 500 3
    Compound: RIF
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability
    		[PMID: 37423128]
    Vero CC50
    > 150 6
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 26498570]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 29227930]
    Vero IC50
    > 200 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30145051]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30025351]
    Vero CC50
    > 32 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31353295]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30690301]
    Vero CC50
    > 50 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiterGlo assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiterGlo assay
    		[PMID: 22691154]
    Vero CC50
    >32 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31353295]
    Vero IC50
    > 50 3
    Compound: 52
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay
    		[PMID: 28094223]
    Vero CC50
    >128 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells incubated for 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells incubated for 72 hrs by MTT assay
    		[PMID: 31352245]
    Vero CC50
    > 500 6
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 23062712]
    Vero CC50
    >75.9 3
    Compound: rifampicin
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as cell viability after 72 hr by MTT assay
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as cell viability after 72 hr by MTT assay
    		10.1007/s00044-011-9638-9
    Vero IC50
    > 62.5 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay
    		[PMID: 24721315]
    Vero CC50
    128 6
    Compound: Rifampicin
    Cytotoxicity in African green monkey Vero cells
    Cytotoxicity in African green monkey Vero cells
    		[PMID: 31358466]
    Vero IC50
    > 62.5 6
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 23352268]
    Vero IC50
    147 6
    Compound: Rifampin
    Compound was tested for its cytotoxicity on Vero cells
    Compound was tested for its cytotoxicity on Vero cells
    		[PMID: 10762047]
    Vero IC50
    > 62.5 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20056418]
    Vero IC50
    >74.5 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero after 72 hrs by MTT assay
    		[PMID: 20576327]
    Hepatocyte EC50
    0.98 3
    Compound: Rifampicin
    Induction of CYP2B6 mRNA expression in human donor hepatocytes after 48 hrs by real-time PCR method
    Induction of CYP2B6 mRNA expression in human donor hepatocytes after 48 hrs by real-time PCR method
    		[PMID: 22815312]
    Vero IC50
    142.9 6
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 24224794]
    Vero IC50
    > 64 6
    Compound: RFP
    Cytotoxicity against African green monkey Vero cells after 48 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 48 hrs by MTT assay
    		[PMID: 36150342]
    Hepatocyte EC50
    1.3 3
    Compound: Rifampicin
    Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS method
    Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS method
    		[PMID: 22815312]
    Vero IC50
    > 64 6
    Compound: Rfp
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 34126456]
    Vero IC50
    58 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells
    Cytotoxicity against African green monkey Vero cells
    		[PMID: 23850103]
    Hepatocyte IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against primary human hepatocytes assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against primary human hepatocytes assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    Vero IC50
    > 74.5 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero after 72 hrs by MTT assay
    		[PMID: 20576327]
    Vero IC50
    89.3 6
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 18818073]
    Vero CC50
    > 75.9 3
    Compound: rifampicin
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as cell viability after 72 hr by MTT assay
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as cell viability after 72 hr by MTT assay
    		10.1007/s00044-011-9638-9
    Vero IC50
    97.9 3
    Compound: rifampin
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 19371071]
    Vero IC50
    > 75.9 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19131245]
    Vero IC50
    >122 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells
    Cytotoxicity against African green monkey Vero cells
    		[PMID: 32031795]
    Vero CC50
    > 75.94 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20615698]
    Huh-7 IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against human HuH7 cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against human HuH7 cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    Vero IC50
    >158 6
    Compound: rifampin
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 9677287]
    Huh-7 IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against human HuH7 cells assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against human HuH7 cells assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    Vero IC50
    > 75.94 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19942326]
    Vero IC50
    >182 3
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 24314672]
    Vero IC50
    > 75.94 3
    Compound: rifampicin
    Cytotoxicity against Vero cells after 72 hrs by MTT assay
    Cytotoxicity against Vero cells after 72 hrs by MTT assay
    		[PMID: 17276683]
    Vero IC50
    >256 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells
    Cytotoxicity against African green monkey Vero cells
    		[PMID: 28574259]
    Vero IC50
    > 77.4 3
    Compound: Rifampicin
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells after 72 hr
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells after 72 hr
    		10.1007/s00044-010-9322-5
    Vero IC50
    >64 6
    Compound: RFP
    Cytotoxicity against African green monkey Vero cells after 48 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 48 hrs by MTT assay
    		[PMID: 36150342]
    Vero IC50
    100 6
    Compound: rifampin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19926361]
    Vero IC50
    113 3
    Compound: RMP, RFC
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 21691438]
    Vero IC50
    108 3
    Compound: RMP, rifampicin
    Cytotoxicity against african green monkey Vero cells by tetrazolium dye reduction assay
    Cytotoxicity against african green monkey Vero cells by tetrazolium dye reduction assay
    		[PMID: 24084159]
    Vero IC50
    122 3
    Compound: 1
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 20000470]
    Vero IC50
    113 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiter assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiter assay
    		[PMID: 22391032]
    Vero IC50
    122 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 19863050]
    Vero IC50
    122 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 20022500]
    Vero IC50
    113 3
    Compound: rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by CellTiter 96 assay
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by CellTiter 96 assay
    		[PMID: 24909079]
    Vero IC50
    113 3
    Compound: RMP, RFC
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 21691438]
    Vero IC50
    127 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 19757815]
    Vero IC50
    122 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 20022500]
    Vero IC50
    127 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by Cell titer assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by Cell titer assay
    		[PMID: 19271749]
    Vero IC50
    122 3
    Compound: 1
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 20000470]
    Vero IC50
    113 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiter assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiter assay
    		[PMID: 22391032]
    Vero IC50
    122 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 19863050]
    Vero IC50
    138.3 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
    		[PMID: 19119013]
    Vero IC50
    125 3
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells by colorimetric assay
    Cytotoxicity against african green monkey Vero cells by colorimetric assay
    		[PMID: 20116900]
    Vero IC50
    >100 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS/PMS assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS/PMS assay
    		[PMID: 29259747]
    Vero IC50
    127 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 19757815]
    Vero IC50
    132.5 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS-PMS assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS-PMS assay
    		[PMID: 24079882]
    Vero IC50
    127 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by Cell titer assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by Cell titer assay
    		[PMID: 19271749]
    Vero IC50
    >100 6
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS-PMS assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS-PMS assay
    		[PMID: 24087924]
    Vero IC50
    132.5 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS-PMS assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS-PMS assay
    		[PMID: 24079882]
    Vero IC50
    100 6
    Compound: rifampin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19926361]
    Vero IC50
    137.6 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
    		[PMID: 31951961]
    Vero IC50
    >100 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19058970]
    Vero IC50
    138.3 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
    		[PMID: 19119013]
    Vero IC50
    >100 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20233660]
    Vero CC50
    180 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assat
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assat
    		[PMID: 21146257]
    Vero IC50
    >62.5 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20056418]
    Vero CC50
    500 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28720502]
    Vero IC50
    >62.5 6
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 23352268]
    Vero CC50
    500 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28646656]
    Vero IC50
    >75.9 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19131245]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30690301]
    Vero IC50
    >75.94 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19942326]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30025351]
    Vero IC50
    113 3
    Compound: rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by CellTiter 96 assay
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by CellTiter 96 assay
    		[PMID: 24909079]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 29227930]
    Vero IC50
    >62.5 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay
    		[PMID: 24721315]
    Vero CC50
    512 3
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as decrease in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as decrease in cell viability after 72 hrs by MTT assay
    		[PMID: 30992202]
    Vero IC50
    >100 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 24 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 24 hrs by MTS assay
    		[PMID: 23454512]
    Vero CC50
    512 3
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 30296686]
    Vero IC50
    >64 6
    Compound: Rfp
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 34126456]
    Vero CC50
    7.8 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 29407980]
    Vero IC50
    >200 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30145051]
    Vero IC50
    97.4 6
    Compound: Rifampin
    Cytotoxicity against African green monkey Vero cells by CellTiter 96 aqueous nonradioactive cell proliferation assay
    Cytotoxicity against African green monkey Vero cells by CellTiter 96 aqueous nonradioactive cell proliferation assay
    		[PMID: 30295480]
    Vero IC50
    >50 3
    Compound: 52
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay
    		[PMID: 28094223]
    J774.A1 CC50
    207.03 6
    Compound: rifampin
    Cytotoxicity against mouse J774A1 cells after 24 to 72 hrs by MTT assay
    Cytotoxicity against mouse J774A1 cells after 24 to 72 hrs by MTT assay
    		[PMID: 20934344]
    Vero IC50
    >100 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTS assay
    		[PMID: 27426865]
    J774.A1 IC50
    > 100 3
    Compound: RIF
    Cytotoxicity against mouse J774A1 cells assessed as cell viability after 24 hrs by Trypan blue exclusion assay
    Cytotoxicity against mouse J774A1 cells assessed as cell viability after 24 hrs by Trypan blue exclusion assay
    		[PMID: 24611928]
    Vero IC50
    >100 3
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells at < 10 uM after 3 days
    Cytotoxicity against african green monkey Vero cells at < 10 uM after 3 days
    		[PMID: 22850215]
    J774.A1 IC50
    > 64 6
    Compound: RFP
    Cytotoxicity against mouse J774.A1 cells after 48 hrs by MTT assay
    Cytotoxicity against mouse J774.A1 cells after 48 hrs by MTT assay
    		[PMID: 36150342]
    Vero IC50
    97.4 6
    Compound: Rifampin
    Cytotoxicity against African green monkey Vero cells by CellTiter 96 aqueous nonradioactive cell proliferation assay
    Cytotoxicity against African green monkey Vero cells by CellTiter 96 aqueous nonradioactive cell proliferation assay
    		[PMID: 30295480]
    Vero IC50
    125 3
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells by colorimetric assay
    Cytotoxicity against african green monkey Vero cells by colorimetric assay
    		[PMID: 20116900]
    Vero IC50
    >100 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells by MTS assay
    Cytotoxicity against African green monkey Vero cells by MTS assay
    		[PMID: 26748697]
    Vero IC50
    108 3
    Compound: RMP, rifampicin
    Cytotoxicity against african green monkey Vero cells by tetrazolium dye reduction assay
    Cytotoxicity against african green monkey Vero cells by tetrazolium dye reduction assay
    		[PMID: 24084159]
    Vero IC50
    137.6 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
    		[PMID: 31951961]
    MCF7 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human MCF7 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human MCF7 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    Vero IC50
    >100 6
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells measured after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    Cytotoxicity against African green monkey Vero cells measured after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    		[PMID: 30891129]
    MCF7 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    		[PMID: 27914801]
    Vero IC50
    105 3
    Compound: RMP, rifampin
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells
    		10.1007/s00044-007-9073-0
    Vero IC50
    >77.4 3
    Compound: Rifampicin
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells after 72 hr
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells after 72 hr
    		10.1007/s00044-010-9322-5
    MCF7 GI50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    		[PMID: 28110868]
    MCF7 GI50
    > 121.51 2
    Compound: RP
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    		10.1039/C6MD00278A
    Vero IC50
    >10 6
    Compound: RIP
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell viability after 96 hr by MTT assay
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell viability after 96 hr by MTT assay
    		10.1007/s00044-012-0074-2
    Vero IC50
    >62.5 6
    Compound: Rifa
    Cytotoxicity against Vero cell line
    Cytotoxicity against Vero cell line
    		[PMID: 16759086]
    Vero IC50
    >100 3
    Compound: rifampicin
    Cytotoxicity against Vero cells
    Cytotoxicity against Vero cells
    		[PMID: 17562368]
    MDCK-II IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 24 hrs by MTS assay
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 24 hrs by MTS assay
    		[PMID: 26948407]
    Vero IC50
    >100 6
    Compound: rifampin
    Cytotoxicity against Vero cells
    Cytotoxicity against Vero cells
    		[PMID: 17561405]
    Vero IC50
    >75.94 3
    Compound: rifampicin
    Cytotoxicity against Vero cells after 72 hrs by MTT assay
    Cytotoxicity against Vero cells after 72 hrs by MTT assay
    		[PMID: 17276683]
    MDCK-II IC50
    > 20 3
    Compound: RIF
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 48 hrs by MTS assay
    Cytotoxicity against MDCK2-MDR1 cells assessed as cell viability after 48 hrs by MTS assay
    		[PMID: 26948407]
    Vero IC50
    >1000 6
    Compound: Rifampicin
    Cytotoxicity determined in VERO cells at concentrations less than or equal to 62.5 mg/mL or 10 times the MIC against Mycobacterium tuberculosis H37Rv.
    Cytotoxicity determined in VERO cells at concentrations less than or equal to 62.5 mg/mL or 10 times the MIC against Mycobacterium tuberculosis H37Rv.
    		[PMID: 11425535]
    MG-63 IC50
    240 6
    Compound: rifampin
    Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs
    Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs
    		[PMID: 17088489]
    Vero IC50
    110.67 6
    Compound: Rifampin
    In vitro cytotoxicity against VERO cell line
    In vitro cytotoxicity against VERO cell line
    		[PMID: 12139444]
    Vero IC50
    134.48 3
    Compound: Rifampin
    In vitro cytotoxicity against VERO cell line
    In vitro cytotoxicity against VERO cell line
    		[PMID: 12139444]
    Vero IC50
    100 6
    Compound: Rifampin
    Inhibitory concentration required to produce cytotoxicity against VERO cells
    Inhibitory concentration required to produce cytotoxicity against VERO cells
    		[PMID: 16005211]
    MRC5 IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against human MRC5 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    Cytotoxicity against human MRC5 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    		[PMID: 26213786]
    Macrophage IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against mouse bone marrow derived macrophage assessed as growth inhibition after 48 hrs by MTS assay
    Cytotoxicity against mouse bone marrow derived macrophage assessed as growth inhibition after 48 hrs by MTS assay
    		[PMID: 23454512]
    Osteoblast IC50
    130 6
    Compound: rifampin
    Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs
    Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs
    		[PMID: 17088489]
    PANC-1 CC50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human PANC1 cells by MTT assay
    Cytotoxicity against human PANC1 cells by MTT assay
    		[PMID: 27301367]
    PANC-1 GI50
    > 100 6
    Compound: RP
    Cytotoxicity against human PANC1 cells after 48 hrs by MTT assay
    Cytotoxicity against human PANC1 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    PANC-1 GI50
    > 100 6
    Compound: RP
    Growth inhibition of human PANC1 cells by MTT assay
    Growth inhibition of human PANC1 cells by MTT assay
    		[PMID: 30910461]
    PANC-1 GI50
    > 100 6
    Compound: Rifampicin
    Growth inhibition of human PANC1 cells by MTT assay
    Growth inhibition of human PANC1 cells by MTT assay
    		[PMID: 28411559]
    PBMC IC50
    62.92 6
    Compound: RIF
    Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay
    Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay
    		[PMID: 32977201]
    RAW264.7 CC50
    24 3
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells
    Cytotoxicity against mouse RAW264.7 cells
    		[PMID: 33071055]
    RAW264.7 CC50
    80.39 6
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    		[PMID: 33940463]
    RAW264.7 GI50
    700 6
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells
    Cytotoxicity against mouse RAW264.7 cells
    		[PMID: 25921267]
    RAW264.7 GI50
    850 3
    Compound: RIF
    Cytotoxicity against mouse RAW264.7 cells assessed as growth inhibition after 48 hrs by trypan blue assay
    Cytotoxicity against mouse RAW264.7 cells assessed as growth inhibition after 48 hrs by trypan blue assay
    		10.1039/C3MD00251A
    Sf21 IC50
    11.3 3
    Compound: Rifampicin
    Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
    Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
    		[PMID: 21965623]
    Sf21 IC50
    34.7 3
    Compound: Rifampicin
    Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
    Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
    		[PMID: 21965623]
    THP-1 CC50
    > 100 6
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells by MTT assay
    Cytotoxicity against human THP1 cells by MTT assay
    		[PMID: 27301367]
    THP-1 CC50
    > 64 6
    Compound: RFP
    Cytotoxicity against human THP-1 cells incubated for 48 hrs by MTS/PMS assay
    Cytotoxicity against human THP-1 cells incubated for 48 hrs by MTS/PMS assay
    		[PMID: 37300914]
    THP-1 GI50
    0.14 6
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human THP1 cells assessed as growth inhibition by MTT assay
    		[PMID: 28103537]
    THP-1 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human THP1 cells incubated for 1 to 11 days by MTT assay
    Cytotoxicity against human THP1 cells incubated for 1 to 11 days by MTT assay
    		10.1039/C5MD00404G
    THP-1 GI50
    > 100 6
    Compound: RIF
    Cytotoxicity against human THP1 cells by MTT assay
    Cytotoxicity against human THP1 cells by MTT assay
    		[PMID: 27914801]
    THP-1 GI50
    > 100 6
    Compound: RP
    Cytotoxicity against human THP1 cells after 48 hrs by MTT assay
    Cytotoxicity against human THP1 cells after 48 hrs by MTT assay
    		[PMID: 27013391]
    THP-1 IC50
    0.0018 6
    Compound: Rifampicin
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive dormant phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive dormant phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    		[PMID: 26299346]
    THP-1 IC50
    0.0021 6
    Compound: Rifampicin
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive active phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    Anti-tubercular activity against rifampicin, isoniazid, ethambutol and pyrazinamide-sensitive active phage of Mycobacterium tuberculosis H37Ra ATCC 25177 infected in human THP1 cells by neutral red assay
    		[PMID: 26299346]
    THP-1 IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by resazurin dye reduction method
    		[PMID: 26213786]
    Vero CC50
    128 6
    Compound: Rifampicin
    Cytotoxicity in African green monkey Vero cells
    Cytotoxicity in African green monkey Vero cells
    		[PMID: 31358466]
    Vero CC50
    180 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assat
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assat
    		[PMID: 21146257]
    Vero CC50
    500 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28646656]
    Vero CC50
    500 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 28720502]
    Vero CC50
    512 3
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 30296686]
    Vero CC50
    512 3
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as decrease in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as decrease in cell viability after 72 hrs by MTT assay
    		[PMID: 30992202]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 29227930]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30025351]
    Vero CC50
    512 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30690301]
    Vero CC50
    7.8 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 29407980]
    Vero CC50
    > 128 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells incubated for 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells incubated for 72 hrs by MTT assay
    		[PMID: 31352245]
    Vero CC50
    > 150 6
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 26498570]
    Vero CC50
    > 32 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31353295]
    Vero CC50
    > 500 6
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 23062712]
    Vero CC50
    > 50 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiterGlo assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiterGlo assay
    		[PMID: 22691154]
    Vero CC50
    > 75.9 3
    Compound: rifampicin
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as cell viability after 72 hr by MTT assay
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as cell viability after 72 hr by MTT assay
    		10.1007/s00044-011-9638-9
    Vero CC50
    > 75.94 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20615698]
    Vero IC50
    100 6
    Compound: Rifampin
    Inhibitory concentration required to produce cytotoxicity against VERO cells
    Inhibitory concentration required to produce cytotoxicity against VERO cells
    		[PMID: 16005211]
    Vero IC50
    100 6
    Compound: rifampin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19926361]
    Vero IC50
    105 3
    Compound: RMP, rifampin
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells
    		10.1007/s00044-007-9073-0
    Vero IC50
    108 3
    Compound: RMP, rifampicin
    Cytotoxicity against african green monkey Vero cells by tetrazolium dye reduction assay
    Cytotoxicity against african green monkey Vero cells by tetrazolium dye reduction assay
    		[PMID: 24084159]
    Vero IC50
    110.67 6
    Compound: Rifampin
    In vitro cytotoxicity against VERO cell line
    In vitro cytotoxicity against VERO cell line
    		[PMID: 12139444]
    Vero IC50
    113 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiter assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiter assay
    		[PMID: 22391032]
    Vero IC50
    113 3
    Compound: RMP, RFC
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 21691438]
    Vero IC50
    113 3
    Compound: rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by CellTiter 96 assay
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by CellTiter 96 assay
    		[PMID: 24909079]
    Vero IC50
    122 3
    Compound: 1
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 20000470]
    Vero IC50
    122 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 19863050]
    Vero IC50
    122 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 20022500]
    Vero IC50
    125 3
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells by colorimetric assay
    Cytotoxicity against african green monkey Vero cells by colorimetric assay
    		[PMID: 20116900]
    Vero IC50
    127 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by Cell titer assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by Cell titer assay
    		[PMID: 19271749]
    Vero IC50
    127 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by Cell titer assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by Cell titer assay
    		[PMID: 19271749]
    Vero IC50
    127 3
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    Cytotoxicity against african green monkey Vero cells after 72 hrs
    		[PMID: 19757815]
    Vero IC50
    132.5 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS-PMS assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS-PMS assay
    		[PMID: 24079882]
    Vero IC50
    134.48 3
    Compound: Rifampin
    In vitro cytotoxicity against VERO cell line
    In vitro cytotoxicity against VERO cell line
    		[PMID: 12139444]
    Vero IC50
    137.6 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
    		[PMID: 31951961]
    Vero IC50
    138.3 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
    		[PMID: 19119013]
    Vero IC50
    142.9 6
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 24224794]
    Vero IC50
    147 6
    Compound: Rifampin
    Compound was tested for its cytotoxicity on Vero cells
    Compound was tested for its cytotoxicity on Vero cells
    		[PMID: 10762047]
    Vero IC50
    58 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells
    Cytotoxicity against African green monkey Vero cells
    		[PMID: 23850103]
    Vero IC50
    89.3 6
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 18818073]
    Vero IC50
    97.4 6
    Compound: Rifampin
    Cytotoxicity against African green monkey Vero cells by CellTiter 96 aqueous nonradioactive cell proliferation assay
    Cytotoxicity against African green monkey Vero cells by CellTiter 96 aqueous nonradioactive cell proliferation assay
    		[PMID: 30295480]
    Vero IC50
    97.9 3
    Compound: rifampin
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 19371071]
    Vero IC50
    > 100 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells by MTS assay
    Cytotoxicity against African green monkey Vero cells by MTS assay
    		[PMID: 26748697]
    Vero IC50
    > 100 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS/PMS assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTS/PMS assay
    		[PMID: 29259747]
    Vero IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 24 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 24 hrs by MTS assay
    		[PMID: 23454512]
    Vero IC50
    > 100 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTS assay
    Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTS assay
    		[PMID: 27426865]
    Vero IC50
    > 100 3
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells at < 10 uM after 3 days
    Cytotoxicity against african green monkey Vero cells at < 10 uM after 3 days
    		[PMID: 22850215]
    Vero IC50
    > 100 3
    Compound: rifampicin
    Cytotoxicity against Vero cells
    Cytotoxicity against Vero cells
    		[PMID: 17562368]
    Vero IC50
    > 1000 6
    Compound: Rifampicin
    Cytotoxicity determined in VERO cells at concentrations less than or equal to 62.5 mg/mL or 10 times the MIC against Mycobacterium tuberculosis H37Rv.
    Cytotoxicity determined in VERO cells at concentrations less than or equal to 62.5 mg/mL or 10 times the MIC against Mycobacterium tuberculosis H37Rv.
    		[PMID: 11425535]
    Vero IC50
    > 100 6
    Compound: RFP
    Cytotoxicity against african green monkey Vero cells incubated for 48 hrs by CCK8 assay
    Cytotoxicity against african green monkey Vero cells incubated for 48 hrs by CCK8 assay
    		[PMID: 39166949]
    Vero IC50
    > 100 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19058970]
    Vero IC50
    > 100 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20233660]
    Vero IC50
    > 100 6
    Compound: RMP
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS-PMS assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS-PMS assay
    		[PMID: 24087924]
    Vero IC50
    > 100 6
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells measured after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    Cytotoxicity against African green monkey Vero cells measured after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
    		[PMID: 30891129]
    Vero IC50
    > 100 6
    Compound: rifampin
    Cytotoxicity against Vero cells
    Cytotoxicity against Vero cells
    		[PMID: 17561405]
    Vero IC50
    > 10 6
    Compound: RIP
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell viability after 96 hr by MTT assay
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell viability after 96 hr by MTT assay
    		10.1007/s00044-012-0074-2
    Vero IC50
    > 122 3
    Compound: RMP
    Cytotoxicity against African green monkey Vero cells
    Cytotoxicity against African green monkey Vero cells
    		[PMID: 32031795]
    Vero IC50
    > 158 6
    Compound: rifampin
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 9677287]
    Vero IC50
    > 182 3
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells
    Cytotoxicity against african green monkey Vero cells
    		[PMID: 24314672]
    Vero IC50
    > 200 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 30145051]
    Vero IC50
    > 256 6
    Compound: RIF
    Cytotoxicity against African green monkey Vero cells
    Cytotoxicity against African green monkey Vero cells
    		[PMID: 28574259]
    Vero IC50
    > 50 3
    Compound: 52
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay
    		[PMID: 28094223]
    Vero IC50
    > 62.5 6
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 20056418]
    Vero IC50
    > 62.5 6
    Compound: Rifa
    Cytotoxicity against Vero cell line
    Cytotoxicity against Vero cell line
    		[PMID: 16759086]
    Vero IC50
    > 62.5 6
    Compound: Rifampicin
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay
    		[PMID: 24721315]
    Vero IC50
    > 62.5 6
    Compound: Rifampin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 23352268]
    Vero IC50
    > 64 6
    Compound: RFP
    Cytotoxicity against African green monkey Vero cells after 48 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 48 hrs by MTT assay
    		[PMID: 36150342]
    Vero IC50
    > 64 6
    Compound: RFP
    Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay
    		[PMID: 37348296]
    Vero IC50
    > 64 6
    Compound: Rfp
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 34126456]
    Vero IC50
    > 74.5 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero after 72 hrs by MTT assay
    		[PMID: 20576327]
    Vero IC50
    > 75.9 3
    Compound: RIF
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19131245]
    Vero IC50
    > 75.94 3
    Compound: Rifampicin
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    		[PMID: 19942326]
    Vero IC50
    > 75.94 3
    Compound: rifampicin
    Cytotoxicity against Vero cells after 72 hrs by MTT assay
    Cytotoxicity against Vero cells after 72 hrs by MTT assay
    		[PMID: 17276683]
    Vero IC50
    > 77.4 3
    Compound: Rifampicin
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells after 72 hr
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells after 72 hr
    		10.1007/s00044-010-9322-5
    In Vitro

    Rifampicin (100 microg/mL) can block the functional activity of P-glycoprotein. Rifampicin is not a substract for P-glycoprotein. The mechanism of rifampicin resistance is unassociated with the functional activity of P-glycoprotein[3].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Rifampicin Related Antibodies
    In Vivo

    Rifampicin (200, 400 mg/kg) can induce fatty liver at high concentration[1]. Rifampicin (30 mg/kg, i.p.) treatment of S464P biofilms in vivo results in a slight decline, but earlier rebinds in bioluminescence from these catheters compared with the parental signal, whereas rifampicin has no affect on bioluminescence in mice infected with mutant H481Y[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    Essai clinique
    Masse moléculaire

    822.94

    Formule

    C43H58N4O12
    CAS No.
    Appearance

    Solid

    Color

    Orange to red

    SMILES

    OC(C(/C=N/N1CCN(C)CC1)=C(NC(/C(C)=C\C=C\[C@@H]([C@@H]([C@@H](C)[C@H]2O)O)C)=O)C(O)=C3C(O)=C4C)=C3C5=C4O[C@](C)(O/C=C/[C@@H]([C@H]([C@@]([C@@H]2C)([H])OC(C)=O)C)OC)C5=O
    Livraison

    Room temperature in continental US; may vary elsewhere.
    Stockage
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Solvant et solubilité
    In Vitro: 

    DMSO : 70 mg/mL (85.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.2152 mL 6.0758 mL 12.1516 mL
    5 mM 0.2430 mL 1.2152 mL 2.4303 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    • Calculateur de molarité

    • Calculateur de dilution

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo:

    Select the appropriate dissolution method based on your experimental animal and administration route.

    For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
    To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: 2.5 mg/mL (3.04 mM); Clear solution; Need ultrasonic

      This protocol yields a clear solution of 2.5 mg/mL.

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

      Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
    • Protocol 2

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

      Solubility: ≥ 2.5 mg/mL (3.04 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

      Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Please enter your animal formula composition:
    %
    DMSO +
    % 
    +
    %
    Tween-80 +
    %
    Saline
    Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
    The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
    Calculation results:
    Working solution concentration: mg/mL
    Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
    Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
     If the continuous dosing period exceeds half a month, please choose this protocol carefully.
    Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
    Pureté et documentation

    Purity: 98.23%

    SDS (393 KB)

    COA (254 KB) HNMR (336 KB) RP-HPLC (217 KB) MS (231 KB)

    Instruction de manipulation (2659 KB)
    Références
    Administration animale
    [2]

    Briefly, 1 cm Teflon catheter (14-gauge) carrying 104 cfu S. aureus, either the parental strain Xen 29 or the RifR mutants S464P or H481Y, are implanted subcutaneously in groups of nine mice per strain. One catheter segment is inserted on each side of each animal. Six days after the implantation of the catheters, five mice from each group are treated with rifampicin at 30 mg/kg intraperitoneally in 0.1 mL saline, twice daily for four consecutive days. The remaining four mice in each group are left untreated as controls. At various time points during the infection, the mice are anaesthetized using a constant flow of 1.5% isoflurane from the IVIS® manifold, and imaged using an IVIS® Image System 100 Series. The bioluminescent signals (photons/s) emitted from the mice are analysed using LivingImage® software and plotted over the course of infection. The mice are sacrificed 20 days after infection (11 days after final rifampicin treatment). The catheters are surgically removed and the bacteria are detached by sonication for determination of bacterial burdens on the catheters.

    MCE n'a pas confirmé de manière indépendante l'exactitude de ces méthodes. Ils sont pour référence seulement.
    Références

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO 1 mM 1.2152 mL 6.0758 mL 12.1516 mL 30.3789 mL
    5 mM 0.2430 mL 1.2152 mL 2.4303 mL 6.0758 mL
    10 mM 0.1215 mL 0.6076 mL 1.2152 mL 3.0379 mL
    15 mM 0.0810 mL 0.4051 mL 0.8101 mL 2.0253 mL
    20 mM 0.0608 mL 0.3038 mL 0.6076 mL 1.5189 mL
    25 mM 0.0486 mL 0.2430 mL 0.4861 mL 1.2152 mL
    30 mM 0.0405 mL 0.2025 mL 0.4051 mL 1.0126 mL
    40 mM 0.0304 mL 0.1519 mL 0.3038 mL 0.7595 mL
    50 mM 0.0243 mL 0.1215 mL 0.2430 mL 0.6076 mL
    60 mM 0.0203 mL 0.1013 mL 0.2025 mL 0.5063 mL
    80 mM 0.0152 mL 0.0759 mL 0.1519 mL 0.3797 mL
    • No file chosen (Maximum size is: 1024 Kb)
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    • Your name will appear on the site.

    Rifampicin Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Rifampicin13292-46-1Rifampin Rifamycin AMPBacterialInfluenza VirusAntibioticOrthopoxvirusInhibitorinhibitorinhibit

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