2. Anti-infection
  3. Bacterial Influenza Virus Antibiotic
  4. Rifampicin-d8

Rifampicin-d8  (Synonyms: Rifampin-d8; Rifamycin AMP-d8)

Cat. No.: HY-B0272S1 Purity: 97.62%
COA
SDS
Handling Instructions Technical Support

Rifampicin-d8 (Rifampin-d8) is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

For research use only. We do not sell to patients.

Rifampicin-d<sub>8</sub>

Rifampicin-d8 Chemical Structure

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500 μg Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
1 mg Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
5 mg In-stock
10 mg   Get quote  
50 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Rifampicin-d8:

Rifampicin-d8 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Rifampicin-d8 (Rifampin-d8) is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Rifampicin-d8 Related Antibodies
Molecular Weight

830.99

Formula

C43H50D8N4O12
Unlabeled CAS
Appearance

Solid

Color

Orange to reddish brown

SMILES

OC(C(/C=N/N1C([2H])([2H])C([2H])([2H])N(C)C([2H])([2H])C1([2H])[2H])=C(NC(/C(C)=C\C=C\[C@@H]([C@@H]([C@@H](C)[C@H]2O)O)C)=O)C(O)=C3C(O)=C4C)=C3C5=C4O[C@](C)(O/C=C/[C@@H]([C@H]([C@@]([C@@H]2C)([H])OC(C)=O)C)OC)C5=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (60.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2034 mL 6.0169 mL 12.0338 mL
5 mM 0.2407 mL 1.2034 mL 2.4068 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2034 mL 6.0169 mL 12.0338 mL 30.0846 mL
5 mM 0.2407 mL 1.2034 mL 2.4068 mL 6.0169 mL
10 mM 0.1203 mL 0.6017 mL 1.2034 mL 3.0085 mL
15 mM 0.0802 mL 0.4011 mL 0.8023 mL 2.0056 mL
20 mM 0.0602 mL 0.3008 mL 0.6017 mL 1.5042 mL
25 mM 0.0481 mL 0.2407 mL 0.4814 mL 1.2034 mL
30 mM 0.0401 mL 0.2006 mL 0.4011 mL 1.0028 mL
40 mM 0.0301 mL 0.1504 mL 0.3008 mL 0.7521 mL
50 mM 0.0241 mL 0.1203 mL 0.2407 mL 0.6017 mL
60 mM 0.0201 mL 0.1003 mL 0.2006 mL 0.5014 mL
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Rifampicin-d8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rifampicin-d8Rifampin-d8 Rifamycin AMP-d8BacterialInfluenza VirusAntibioticInhibitorinhibitorinhibit

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