Search Result

Results for "

Ebp1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (4) Aminopeptidase (2) AMPK (6) Amyloid-β (1) Androgen Receptor (2) Apoptosis (10) ATM/ATR (3) Autophagy (4) Bacterial (4) c-Myc (2) Casein Kinase (1) Caspase (3) CDK (2) Cholinesterase (ChE) (1) Drug Derivative (1) DYRK (1) EGFR (1) Enteropeptidase (2) ERK (2) Eukaryotic Initiation Factor (eIF) (1) FAK (2) Ferroptosis (2) FLT3 (1) Fungal (3) GABA Receptor (1) GSK-3 (1) Hedgehog (2) HIF/HIF Prolyl-Hydroxylase (1) IKK (2) Integrin (2) Keap1-Nrf2 (1) MDM-2/p53 (1) MNK (1) mTOR (21) Necroptosis (1) NF-κB (3) Notch (1) Opioid Receptor (2) PARP (2) PI3K (3) Pim (5) PTEN (1) Reference Standards (3) Ribosomal S6 Kinase (RSK) (1) Small Interfering RNA (siRNA) (8) STAT (3) VEGFR (1) γ-secretase (1)
By Research Areas:	Cancer (30) Infection (4) Inflammation/Immunology (9) Metabolic Disease (5) Neurological Disease (4)
Oligonucleotides:	Rat Pre-designed siRNA Sets (3) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (3) siRNAs (8)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12461

WS6	PI3K EGFR GABA Receptor FLT3 IKK	Neurological Disease Metabolic Disease Inflammation/Immunology
WS6 is an IkB kinase and *EBP1* inhibitor, with IC₅₀ values of 0.24 nM, 0.21 nM, and 40.48 nM in MV4-11, MOLM13, and K562 cells, respectively. WS6 promotes the proliferation of alpha and beta cells in the pancreas, has antioxidant and anti-inflammatory activities, and can alleviate depression like behavior in rats ^[1][2][4].

HY-132168

RMC-5552 5 Publications Verification	mTOR	Cancer
RMC-5552 is a potent and selective *mTORC1* inhibitor. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and *p4EBP1* with IC₅₀s of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows much lower pAKT inhibition (IC₅₀ of 19 nM), resulting in mTORC1/mTORC2 selectivity approaching 40-fold. RMC-5552 has anti-cancer activity ^[1].

HY-12462

WS3	GSK-3 Keap1-Nrf2 Ferroptosis IKK	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
WS3 is an allosteric inhibitor of 14-3-3 (14-3-3ζ: K_d = 2.29 μM). WS3 activates GSK3β by disrupting the binding of 14-3-3-pGSK3β, promotes the ubiquitination and degradation of NRF2, and inhibits the NRF2-ARE signaling pathway (IC₅₀ = 135 nM). It exerts antioxidant inhibition and chemotherapeutic/ferroptosis sensitizing effects in tumors with hyperactivated NRF2. WS3 binds to EBP1/IKKε and promotes the proliferation of β cells and retinal pigment epithelial (RPE) cells, which can be applied to islet regeneration and RPE expansion transplantation . WS3 is applicable to research related to age-related macular degeneration, retinal degeneration and non-small cell lung cancer ^[1] .

HY-N0656A

(+)-Usnic acid 2 Publications Verification	mTOR Bacterial Autophagy	Infection Inflammation/Immunology Cancer
(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits *mTORC1/2* activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer and anti-inflammatory activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium ^[1] .

HY-N1677

2,6-Dimethoxy-1,4-benzoquinone	Akt mTOR Bacterial Fungal AMPK	Infection Metabolic Disease Inflammation/Immunology Cancer
2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, *4E-BP1, and AMPK, and attenuates mTORC1* activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H₂O₂ generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness ^[1] .

HY-143510

RMC-4627	mTOR	Cancer
RMC-4627 is a selective *mTORC1* inhibitor that activates 4EBP1 and inhibits tumor growth.

HY-176761

NSC647889	Apoptosis Autophagy Caspase mTOR	Cancer
NSC647889 is an apoptosis and autophagy inducer. NSC647889 induces apoptosis, inhibits mTOR pathway and abrogates DNA synthesis. NSC647889 triggers LC3-positive vesicle formation, modulates AKT and *4EBP1* phosphorylation and shows heightened caspase-3 activation in multicellular spheroids. NSC647889 can be used for the research of solid cancer tumour, head-neck carcinoma, and colorectal cancer ^[1] .

HY-N6954

Garcinone C 2 Publications Verification	ATM/ATR STAT CDK Hedgehog	Inflammation/Immunology Cancer
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and *4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog* signaling pathway. Garcinone C is orally active ^[1] .

HY-W412264

Pim-1/2 kinase inhibitor 1	Pim	Cancer
Pim-1/2 kinase inhibitor 1 is an orally active pim-1/2 kinase inhibitor. Pim-1/2 kinase inhibitor 1 blocks the ability of Pim kinases to phosphorylate peptides, and inhibits the pim protein kinase directed phosphorylation of *4E-BP1* and p27 ^Kip1. Pim-1/2 kinase inhibitor 1 can be used in study of cancer, especially prostate cancer ^[1].

HY-134903

(32-Carbonyl)-RMC-5552	mTOR	Cancer
(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC₅₀s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2) ^[1].

HY-114267

Cbz-B3A	mTOR	Others
Cbz-B3A is a potent and selective inhibitor of *mTORC1* signaling that appear to bind to ubiquilins 1, 2, and 4, and Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1).

HY-115590

JP-11646	Pim Caspase Apoptosis Necroptosis PARP NF-κB	Cancer
JP-11646 is a pan-PIM inhibitor with increased potency against PIM2 (IC₅₀ = 0.5 nM). JP11646 is freely reversible and ATP non-competitive. JP-11646 results in a decrease of PIM1, 2, and 3 mRNA. JP-11646 can effectively inhibit cell viability in small cell lung cancer (SCLC) and large cell neuroendocrine carcinomas of the lung (LCNEC). JP-11646 can cause a decrease in p-4EBP-1 protein, increasing the cleavage of caspases while decreasing caspase-3. JP-11646 induces apoptosis or necroptosis in cells. JP-11646 leads to reductions in MYC paralogs. JP-11646 can be used for the study of SCLC, LCNEC, human acute leukemia (AML), multiple myeloma (MM), and triple-negative breast cancer (TNBC) ^[1] .

HY-W348485

WRX606	mTOR	Cancer
WRX606 is an orally active nonrapalog inhibitor for mTOR complex 1 (mTORC1M). WRX606 inhibits the phosphorylation of mTORC1 substrate S6 kinase 1 (S6K1) (IC₅₀ = 10 nM) and eukaryotic translation initiation factor 4E binding protein (p-4E-BP1) (IC₅₀ = 0.27 μM) in MCF-7 cells. WRX606 suppresses tumor growth in mice without promotion of metastasis. WRX606 can be studied in research as an antitumor agent ^[1] .

HY-P10323

T7 Peptide Tumstatin (74-98), human	Integrin FAK mTOR Apoptosis	Cancer
T7 Peptide is a protein synthesis inhibitor and anti-angiogenic agent, with a K_d of 10 nM for human transferrin receptor. T7 Peptide inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of *4E-BP1* in endothelial cells. T7 Peptide induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma ^[1] .

HY-P10323A

T7 Peptide TFA Tumstatin (74-98), human TFA	Integrin FAK mTOR Apoptosis	Cancer
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K_d of 10 nM for human transferrin receptor. T7 Peptide TFA inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of *4E-BP1* in endothelial cells. T7 Peptide TFA induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide TFA is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma ^[1] .

HY-N11709

Theasaponin E1	Apoptosis VEGFR ATM/ATR PTEN Akt mTOR HIF/HIF Prolyl-Hydroxylase NF-κB Notch Cholinesterase (ChE) Amyloid-β γ-secretase Ferroptosis Fungal	Infection Neurological Disease Metabolic Disease Cancer
Theasaponin E1 is an orally effective tea saponin. Theasaponin E1 inhibits the proliferation of cancer cells by activating apoptosis. Theasaponin E1 inhibits angiogenesis in ovarian cancer cells and HUVECs by reducing the expression of VEGF. Theasaponin E1 upregulates the phosphorylation level of ATM protein and the expression level of PTEN protein in cancer cells, decreases the phosphorylation levels of Akt, mTOR, p70S6K and *4E-BP1* proteins, downregulates the expression of *HIF-1α* and NF-κB, and reduces the protein expression of Notch ligands Dll4 and *Jagged1. Theasaponin E1 exerts neuroprotective effects by inhibiting the activity of acetylcholinesterase, activating α-secretase* and neprilysin, reducing the concentration of Aβ, and inhibiting the activities of β-secretase and γ-secretase. Theasaponin E1 exhibits toxic effects on cancer cells and quinone reductase-inducing activity, and inhibits tumor growth in vivo. Theasaponin E1 induces ferroptosis in Pomacea canaliculata by synergistically disrupting cholesterol homeostasis and sphingolipid metabolism. Theasaponin E1 possesses anti-biofilm activity against Candida albicans. Theasaponin E1 can be used in the research of ovarian cancer, obesity, Alzheimer's disease and fungal infections ^[1] .

HY-130723A

AMPK activator 2 hydrochloride	AMPK	Cancer
AMPK activator 2 (compound 7a) hydrochloride, a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 hydrochloride inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549) ^[1].

HY-RS09254

NFKB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NFKB1 Human Pre-designed siRNA Set A contains three designed siRNAs for NFKB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NFKB1 Human Pre-designed siRNA Set A NFKB1 Human Pre-designed siRNA Set A

HY-124348

DM-PIT-1 3,5-Dimethyl PIT-1	PI3K	Cancer
DM-PIT-1 is a PIP3/PH (phosphatidylinositol-3,4,5-triphosphate/Pleckstrin) interaction inhibitor. DM-PIT-1 decreases he expression of P-Akt, P-GSK-3-β, P-p70S6K, P-S6, P-4E-BP1. DM-PIT-1 induces apoptosis and shows anticancer activity. DM-PIT-1 has the potential for the research of ovarian cancer ^[1] .

HY-115869

RMC-4529	mTOR	Cancer
RMC-4529 has an IC₅₀ value of 1.0 nM against p-4E-BP1-(T37/46) in mTOR kinase cellular assay.

HY-149292

SR-4133	Casein Kinase	Cancer
SR-4133 is a potent and highly *CK1ε* selective inhibitor with an IC₅₀ of 58 nM. SR-4133 binds to the ATP-binding site of CK1ε. SR-4133 displays nanomolar growth inhibition of bladder cancer cells, and inhibits the phosphorylation of 4E-BP1 ^[1].

HY-P11642A

Sialorphin TFA	Enteropeptidase Aminopeptidase Opioid Receptor ERK mTOR Androgen Receptor	Inflammation/Immunology
Sialorphin TFA is a neutral endopeptidase (NEP) and aminopeptidase N (APN) inhibitor that responds to androgen signals. Sialorphin TFA blocks the degradation of endogenous opioid peptides and interacts with μ-, δ-, κ-opioid receptors. Sialorphin TFA regulates the ERK/mTOR signaling pathway by inducing cell cycle arrest, enhancing *ERK1/2* activity, and reducing the phosphorylation levels of *mTOR, 4E-BP1, p70S6K; accordingly, Sialorphin TFA exhibits antiproliferative activity against colorectal cancer, glioma and prostate cancer cells without cytotoxicity. In addition, Sialorphin TFA also produces antinociceptive responses, regulates sexual behavior, relaxes corpus cavernosum smooth muscle, and alleviates experimental colitis. Sialorphin TFA is also a copper (II) ion-binding ligand*. Sialorphin TFA has been used in mechanistic studies related to cancer, pain management and inflammatory bowel disease ^[1] .

HY-RS26734

Eif4ebp1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Eif4ebp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Eif4ebp1 Rat Pre-designed siRNA Set A Eif4ebp1 Rat Pre-designed siRNA Set A

HY-RS20227

Eif4ebp1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Eif4ebp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Eif4ebp1 Mouse Pre-designed siRNA Set A Eif4ebp1 Mouse Pre-designed siRNA Set A

HY-RS04277

EIF4EBP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
EIF4EBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EIF4EBP1 Human Pre-designed siRNA Set A EIF4EBP1 Human Pre-designed siRNA Set A

HY-RS20461

Pa2g4 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pa2g4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pa2g4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pa2g4 Mouse Pre-designed siRNA Set A Pa2g4 Mouse Pre-designed siRNA Set A

HY-RS09256

Nfkb1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA) NF-κB	Others
Nfkb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nfkb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nfkb1 Rat Pre-designed siRNA Set A Nfkb1 Rat Pre-designed siRNA Set A

HY-RS09947

PA2G4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PA2G4 Human Pre-designed siRNA Set A contains three designed siRNAs for PA2G4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PA2G4 Human Pre-designed siRNA Set A PA2G4 Human Pre-designed siRNA Set A

HY-130723

AMPK activator 2	AMPK	Cancer
AMPK activator 2 (compound 7a), a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549) ^[1].

HY-111370

mTOR inhibitor-2	mTOR	Cancer
mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC₅₀ of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates ^[1].

HY-N0656AR

(+)-Usnic acid (Standard)	Reference Standards mTOR Bacterial Autophagy	Cancer
(+)-Usnic acid (Standard) is the analytical standard of (+)-Usnic acid. This product is intended for research and analytical applications. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity ^[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium .

HY-N6954R

Garcinone C (Standard)	Reference Standards ATM/ATR STAT CDK Hedgehog	Inflammation/Immunology Cancer
Garcinone C (Standard) is the analytical standard of Garcinone C. This product is intended for research and analytical applications. Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and *4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog* signaling pathway. Garcinone C is orally active ^[1] .

HY-N1677R

2,6-Dimethoxy-1,4-benzoquinone (Standard)	Reference Standards Akt mTOR Bacterial Fungal AMPK	Infection Metabolic Disease Inflammation/Immunology Cancer
2,6-Dimethoxy-1,4-benzoquinone (Standard) is the analytical standard of 2,6-Dimethoxy-1,4-benzoquinone (HY-N1677). This product is intended for research and analytical applications. 2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness.

HY-RS26970

Pa2g4 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pa2g4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pa2g4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pa2g4 Rat Pre-designed siRNA Set A Pa2g4 Rat Pre-designed siRNA Set A

HY-182957

MNK/PIM-IN-2	MNK Pim Apoptosis Caspase Eukaryotic Initiation Factor (eIF) PARP c-Myc	Cancer
MNK/PIM-IN-2 is a Mnk/Pim kinase inhibitor with an IC₅₀ of 32 nM for *Mnk1, 3 nM for Mnk2, and 37 nM for Pim1. MNK/PIM-IN-2 reduces the levels of p-eIF4E* and *p-4EBP1. MNK/PIM-IN-2 induces cell cycle arrest, apoptosis (apoptosis*) and exerts antiproliferative effects in leukemia cells. MNK/PIM-IN-2 can be used in studies related to leukemia ^[1].

HY-176948

M-1111	mTOR	Cancer
M-1111 is a Rapa-Link inhibitor. M-1111 is covalently linked by Rapamycin (HY-10219) and an inhibitor of the active site mTOR. M-1111 has strong inhibitory activity on the *mTORC1* signaling pathway (pS6 and *p4E-BP1). M-1111 has nanomolar-level inhibitory activity against various cancer cells. M-1111 completely inhibits p4E-BP1* without inhibiting pAkt S473. M-1111 can be used for research on liver cancer, kidney cancer, and colorectal cancer ^[1].

HY-181650

T133	mTOR Akt Ribosomal S6 Kinase (RSK) Apoptosis Autophagy PI3K	Cancer
T133 is an orally active ATP-competitive mTOR inhibitor with an IC₅₀ of 0.34 nM and a K_i of 0.17 nM. T133 suppresses phosphorylation of AKT, *S6K1, and 4EBP1. T133 inhibits cancer cell proliferation and migration, induces apoptosis, cell cycle arrest, and autophagy*. T133 exhibits dose-dependent antitumor efficacy in xenograft mouse models. T133 can be used for the research of cancer, such as gastric cancer and lung cancer ^[1].

HY-181925

FD2024	Apoptosis Pim mTOR	Cancer
FD2024 is a pan-PIM kinase inhibitor with IC₅₀ values of 0.17 nM, 1.86 nM, and 0.38 nM against *PIM-1, PIM-2, and PIM-3, respectively. FD2024 induces cell apoptosis. FD2024 inhibits the phosphorylation of mTOR, p70S6K, S6, 4EBP1, and BAD* proteins. FD2024 exhibits anti-acute myeloid leukemia activity. FD2024 can be used in studies related to acute myeloid leukemia ^[1].

HY-N15121

4-O-Methyl-ascochlorin	Drug Derivative Apoptosis c-Myc AMPK mTOR	Cancer
4-O-Methyl-ascochlorin (Compound MAC) is a derivative of Ascochlorin (HY-101021). 4-O-Methyl-ascochlorin can selectively induce apoptosis of K562 leukemia cells, cause G1 phase arrest and downregulate c-Myc expression. 4-O-Methyl-ascochlorin can promote the phosphorylation of AMPK and inhibit the phosphorylation of mTOR and its target proteins, including p70S6 K and 4E-BP-1. 4-O-Methyl-ascochlorin can be used for research of leukemia ^[1].

HY-P11642

Sialorphin	ERK Androgen Receptor Opioid Receptor Enteropeptidase mTOR Aminopeptidase	Neurological Disease Inflammation/Immunology Cancer
Sialorphin is a neutral endopeptidase (NEP) and aminopeptidase N (APN) inhibitor that responds to androgen signals. Sialorphin blocks the degradation of endogenous opioid peptides and interacts with μ-, δ-, κ-opioid receptors. Sialorphin regulates the ERK/mTOR signaling pathway by inducing cell cycle arrest, enhancing *ERK1/2* activity, and reducing the phosphorylation levels of *mTOR, 4E-BP1, p70S6K; accordingly, Sialorphin exhibits antiproliferative activity against colorectal cancer, glioma and prostate cancer cells without cytotoxicity. In addition, Sialorphin also produces antinociceptive responses, regulates sexual behavior, relaxes corpus cavernosum smooth muscle, and alleviates experimental colitis. Sialorphin is also a copper (II) ion-binding ligand*. Sialorphin has been used in mechanistic studies related to cancer, pain management and inflammatory bowel disease ^[1] .

HY-122670

VS-II-173	Pim Apoptosis AMPK DYRK STAT MDM-2/p53	Cancer
VS-II-173 is a pan-Pim kinase inhibitor with IC₅₀ values of 0.07 μM and 0.02 μM for *Pim1* and Pim3, respectively, and a residual activity of 46% for Pim2 at 1 μM. VS-II-173 also inhibits kinases such as HIPK2, PRK2, *RSK1, DYRK1a* and AMPK_α1, selectively inhibiting acute myeloid leukemia (AML) cells with significantly lower toxicity to non-malignant cells (EC₅₀ > 30 μM). VS-II-173 weakens the phosphorylation of substrates such as Stat5 (Y694), MDM2 (S166), Bad (S112), and 4E-BP1 (T37/46) by inhibiting Pim kinase-mediated signaling pathways, blocking pro-survival signals in AML cells and inducing apoptosis. VS-II-173 synergistically enhances anti-AML activity when combined with Daunorubicin (HY-13062A). VS-II-173 can be used in AML research, especially for AML with FLT3-ITD mutations and *NPM1* mutations ^[1] .

Cat. No.	Product Name	Target	Research Area

HY-P10323

T7 Peptide Tumstatin (74-98), human	Integrin FAK mTOR Apoptosis	Cancer
T7 Peptide is a protein synthesis inhibitor and anti-angiogenic agent, with a K_d of 10 nM for human transferrin receptor. T7 Peptide inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of *4E-BP1* in endothelial cells. T7 Peptide induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma ^[1] .

HY-P10323A

T7 Peptide TFA Tumstatin (74-98), human TFA	Integrin FAK mTOR Apoptosis	Cancer
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K_d of 10 nM for human transferrin receptor. T7 Peptide TFA inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of *4E-BP1* in endothelial cells. T7 Peptide TFA induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide TFA is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma ^[1] .

HY-P11642A

Sialorphin TFA	Enteropeptidase Aminopeptidase Opioid Receptor ERK mTOR Androgen Receptor	Inflammation/Immunology
Sialorphin TFA is a neutral endopeptidase (NEP) and aminopeptidase N (APN) inhibitor that responds to androgen signals. Sialorphin TFA blocks the degradation of endogenous opioid peptides and interacts with μ-, δ-, κ-opioid receptors. Sialorphin TFA regulates the ERK/mTOR signaling pathway by inducing cell cycle arrest, enhancing *ERK1/2* activity, and reducing the phosphorylation levels of *mTOR, 4E-BP1, p70S6K; accordingly, Sialorphin TFA exhibits antiproliferative activity against colorectal cancer, glioma and prostate cancer cells without cytotoxicity. In addition, Sialorphin TFA also produces antinociceptive responses, regulates sexual behavior, relaxes corpus cavernosum smooth muscle, and alleviates experimental colitis. Sialorphin TFA is also a copper (II) ion-binding ligand*. Sialorphin TFA has been used in mechanistic studies related to cancer, pain management and inflammatory bowel disease ^[1] .

HY-P11642

Sialorphin	ERK Androgen Receptor Opioid Receptor Enteropeptidase mTOR Aminopeptidase	Neurological Disease Inflammation/Immunology Cancer
Sialorphin is a neutral endopeptidase (NEP) and aminopeptidase N (APN) inhibitor that responds to androgen signals. Sialorphin blocks the degradation of endogenous opioid peptides and interacts with μ-, δ-, κ-opioid receptors. Sialorphin regulates the ERK/mTOR signaling pathway by inducing cell cycle arrest, enhancing *ERK1/2* activity, and reducing the phosphorylation levels of *mTOR, 4E-BP1, p70S6K; accordingly, Sialorphin exhibits antiproliferative activity against colorectal cancer, glioma and prostate cancer cells without cytotoxicity. In addition, Sialorphin also produces antinociceptive responses, regulates sexual behavior, relaxes corpus cavernosum smooth muscle, and alleviates experimental colitis. Sialorphin is also a copper (II) ion-binding ligand*. Sialorphin has been used in mechanistic studies related to cancer, pain management and inflammatory bowel disease ^[1] .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0656A

(+)-Usnic acid 2 Publications Verification	other families Classification of Application Fields Ketones, Aldehydes, Acids Plants Lichen Disease Research Fields Cancer	mTOR Bacterial Autophagy
(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits *mTORC1/2* activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer and anti-inflammatory activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium ^[1] .

HY-N1677

2,6-Dimethoxy-1,4-benzoquinone	Infection Quinones other families Classification of Application Fields Metabolic Disease Benzene Quinones Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Akt mTOR Bacterial Fungal AMPK
2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, *4E-BP1, and AMPK, and attenuates mTORC1* activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H₂O₂ generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness ^[1] .

HY-N6954

Garcinone C 2 Publications Verification	other families Xanthones Classification of Application Fields Garcinia oblongifolia Champ. ex Benth. Guttiferae Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	ATM/ATR STAT CDK Hedgehog
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and *4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog* signaling pathway. Garcinone C is orally active ^[1] .

HY-N11709

Theasaponin E1	Triterpenes Structural Classification Terpenoids Camellia sinensis (L.) O. Ktze. Plants Source Classification Theaceae	Apoptosis VEGFR ATM/ATR PTEN Akt mTOR HIF/HIF Prolyl-Hydroxylase NF-κB Notch Cholinesterase (ChE) Amyloid-β γ-secretase Ferroptosis Fungal
Theasaponin E1 is an orally effective tea saponin. Theasaponin E1 inhibits the proliferation of cancer cells by activating apoptosis. Theasaponin E1 inhibits angiogenesis in ovarian cancer cells and HUVECs by reducing the expression of VEGF. Theasaponin E1 upregulates the phosphorylation level of ATM protein and the expression level of PTEN protein in cancer cells, decreases the phosphorylation levels of Akt, mTOR, p70S6K and *4E-BP1* proteins, downregulates the expression of *HIF-1α* and NF-κB, and reduces the protein expression of Notch ligands Dll4 and *Jagged1. Theasaponin E1 exerts neuroprotective effects by inhibiting the activity of acetylcholinesterase, activating α-secretase* and neprilysin, reducing the concentration of Aβ, and inhibiting the activities of β-secretase and γ-secretase. Theasaponin E1 exhibits toxic effects on cancer cells and quinone reductase-inducing activity, and inhibits tumor growth in vivo. Theasaponin E1 induces ferroptosis in Pomacea canaliculata by synergistically disrupting cholesterol homeostasis and sphingolipid metabolism. Theasaponin E1 possesses anti-biofilm activity against Candida albicans. Theasaponin E1 can be used in the research of ovarian cancer, obesity, Alzheimer's disease and fungal infections ^[1] .

HY-N0656AR

(+)-Usnic acid (Standard)	Structural Classification other families Ketones, Aldehydes, Acids Plants Lichen	Reference Standards mTOR Bacterial Autophagy
(+)-Usnic acid (Standard) is the analytical standard of (+)-Usnic acid. This product is intended for research and analytical applications. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity ^[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium .

HY-N6954R

Garcinone C (Standard)	Structural Classification other families Xanthones Garcinia oblongifolia Champ. ex Benth. Guttiferae Phenols Polyphenols Plants Source Classification	Reference Standards ATM/ATR STAT CDK Hedgehog
Garcinone C (Standard) is the analytical standard of Garcinone C. This product is intended for research and analytical applications. Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and *4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog* signaling pathway. Garcinone C is orally active ^[1] .

HY-N1677R

2,6-Dimethoxy-1,4-benzoquinone (Standard)	Quinones other families Benzene Quinones Plants Endogenous metabolite Source Classification	Reference Standards Akt mTOR Bacterial Fungal AMPK
2,6-Dimethoxy-1,4-benzoquinone (Standard) is the analytical standard of 2,6-Dimethoxy-1,4-benzoquinone (HY-N1677). This product is intended for research and analytical applications. 2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness.

HY-N15121

4-O-Methyl-ascochlorin	Structural Classification Monophenols Microorganisms Phenols Source Classification	Drug Derivative Apoptosis c-Myc AMPK mTOR
4-O-Methyl-ascochlorin (Compound MAC) is a derivative of Ascochlorin (HY-101021). 4-O-Methyl-ascochlorin can selectively induce apoptosis of K562 leukemia cells, cause G1 phase arrest and downregulate c-Myc expression. 4-O-Methyl-ascochlorin can promote the phosphorylation of AMPK and inhibit the phosphorylation of mTOR and its target proteins, including p70S6 K and 4E-BP-1. 4-O-Methyl-ascochlorin can be used for research of leukemia ^[1].

Species:	Human (3)
Tag:	His (3)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71124

	NFKB1 Protein, Human (His) DNA-binding factor KBF1; Ebp-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	Human	E. coli
	The NFKB1 protein is a subunit of NF-kappa-B and regulates transcription in a variety of biological processes. It forms homodimeric or heterodimeric complexes with RELA/p65, RELB, and NFKB2/p52. NFKB1 Protein, Human (His) is the recombinant human-derived NFKB1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P75726

	EBP1 Protein, Human (His) Proliferation-associated protein 2G4; hG4-1; ErbB3-binding protein 1; PA2G4	Human	E. coli
	EBP1 protein participates in the signal transduction pathway regulated by ERBB3 and is related to growth regulation. As an androgen receptor (AR) corepressor, it is regulated by the ERBB3 ligand neregulin-1/heregulin (HRG). EBP1 Protein, Human (His) is the recombinant human-derived EBP1 protein, expressed by E. coli , with N-His labeled tag.

HY-P70415

	EIF4EBP1 Protein, Human (His) rHuEukaryotic translation initiation factor 4E-binding protein 1/EIF4Ebp1, His; Eukaryotic Translation Initiation Factor 4E-Binding Protein 1; 4E-BP1; eIF4E-Binding Protein 1; Phosphorylated Heat- and Acid-Stable Protein Regulated by Insulin 1; PHAS-I; EIF4Ebp1	Human	E. coli
	EIF4EBP1 is a translation initiation repressor protein that complexly regulates EIF4E activity. In the hypophosphorylated state, EIF4EBP1 competes with EIF4G1/EIF4G3 to inhibit translation by binding to EIF4E. EIF4EBP1 Protein, Human (His) is the recombinant human-derived EIF4EBP1 protein, expressed by E. coli , with N-6*His labeled tag.

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Host:	Mouse (5) Rabbit (9)
Reactivity:	Human (14) Rat (9) Mouse (11) Hamster (2)
Application:	IHC-P (11) ICC/IF (8) IP (7) IHC-F (1) WB (12) FC (4) ELISA (6)
Isotype:	IgG (8) IgG1 (3) IgG/Kappa (1) IgM (1)
Conjugation:	Non-conjugated (14)
Clonality:	Polyclonal (1) Monoclonal (10) Recombinant (3)
Modification:	Phosphorylated (4) Unmodified (7)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82764

	EBP1 Antibody (YA2509) PA2G4; Ebp1; Proliferation-associated protein 2G4; Cell cycle protein p38-2G4 homolog; hG4-1; ErbB3-binding protein 1	WB, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat
	EBP1 Antibody (YA2509) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EBP1.

HY-P85639

	NF-KB p105/p50 Antibody (YA5331) DKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 Ebp1; DNA-binding factor KBF1; Ebp 1; Ebp-1; Ebp1; KBF1; MGC54151; NF kappa B; NF kappaB; NF kappabeta; NF kB1; NFkappaB; NFKB 1; NFKB p105; NFKB p50; Nfkb1; NFKB1_HUMAN; Nuclear factor kappa B DNA binding subunit; Nuclear factor kappa-B, subunit 1; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p105; p50; p84/NF-kappa-B1 p98.	WB	Human
	NF-KB p105/p50 Antibody (YA5331) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to NF-KB p105/p50.

HY-P86373

	NF-κB1 p105/p50 Antibody (YA6065) NFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; Ebp-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	NF-κB1 p105/p50 Antibody (YA6065) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NF-κB1 p105/p50.

HY-P81049

	Phospho-NF-KB p105/p50(Ser337) Antibody NFKB1; NF-KB; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; Ebp-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; DNA-binding factor KBF1; Ebp-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; Nuclear factor NF-kappa-B p50 subunit; NFkB p105 / p50; NFkB p105/p50; nuclear factor kappa B subunit 1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta;	WB, IHC-P, IHC-F, FC, ICC/IF, ELISA	Human, Mouse
	Phospho-NF-KB p105/p50(Ser337) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-NF-KB p105/p50(Ser337).

HY-P80244

	NF-KB p105/p50 Antibody (YA699) DKFZp686C01211 antibody; DNA binding factor KBF1 antibody; DNA binding factor KBF1 Ebp1 antibody; DNA-binding factor KBF1 antibody; Ebp 1 antibody; Ebp-1 antibody; Ebp1 antibody; KBF1 antibody; MGC54151 antibody; NF kappa B antibody; NF kappaB antibody; NF kappabeta antibody; NF kB1 antibody; NFkappaB antibody; NFKB 1 antibody; NFKB p105 antibody; NFKB p50 antibody; Nfkb1 antibody; NFKB1_HUMAN antibody; Nuclear factor kappa B DNA binding subunit antibody; Nuclear factor kappa-B, subunit 1 antibody; Nuclear factor NF kappa B p105 subunit antibody; Nuclear factor NF kappa B p50 subunit antibody; Nuclear factor NF-kappa-B p50 subunit antibody; Nuclear factor of kappa light chain gene enhancer in B cells 1 antibody; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 antibody; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody; p105 antibody; p50 antibody; p84/NF-kappa-B1 p98 antibody; Transcription factor NFKB1 antibody;	WB, ICC/IF, IHC-P	Human, Mouse
	NF-KB p105/p50 Antibody (YA699) is a Mouse-derived and non-conjugated IgM monoclonal antibody, targeting to NF-KB p105/p50.

HY-P80764

	NF-KB p105/p50 Antibody (YA700) NFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; Ebp-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	WB	Human, Mouse, Rat
	NF-KB p105/p50 Antibody (YA700) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NF-KB p105/p50.

HY-P84548

	Phospho-eIF4EBP1 (Ser65) Antibody (YA4245) EIF4Ebp1; BP-1; 4Ebp1; 4E-BP1; PHAS-I	IHC-P, ICC/IF, FC, ELISA	Human
	Phospho-eIF4EBP1 (Ser65) Antibody (YA4245) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Phospho-eIF4EBP1 (Ser65).

HY-P84548A

	Phospho-eIF4EBP1 (Ser65) Antibody (YA4245)(PBS only) EIF4Ebp1; BP-1; 4Ebp1; 4E-BP1; PHAS-I	IHC-P, ICC/IF, FC, ELISA	Human
	Phospho-eIF4EBP1 (Ser65) Antibody (YA4245) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Phospho-eIF4EBP1 (Ser65).

HY-P80526

	eIF4EBP1 Antibody (YA650) EIF4Ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I	WB, IHC-P, IP	Human, Mouse, Rat, Hamster
	eIF4EBP1 Antibody (YA650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to eIF4EBP1.

HY-P86332

	eIF4EBP1 Antibody (YA6024) EIF4Ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	eIF4EBP1 Antibody (YA6024) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to eIF4EBP1.

HY-P80786

	Phospho-eIF4EBP1 (Thr46) Antibody (YA230) EIF4Ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I	WB, IHC-P, IP	Human, Mouse, Rat
	Phospho-eIF4EBP1 (Thr46) Antibody (YA230) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-eIF4EBP1 (Thr46).

HY-P80526A

	eIF4EBP1 Antibody (YA650)(PBS only) EIF4Ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I	WB, IHC-P, IP	Human, Mouse, Rat, Hamster
	eIF4EBP1 Antibody (YA650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to eIF4EBP1.

HY-P86088

	Phospho-eIF4EBP1(Thr37/46) Antibody (YA5780) EIF4Ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I	WB, ICC/IF, ELISA	Human, Mouse, Rat
	Phospho-eIF4EBP1(Thr37/46) Antibody (YA5780) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-eIF4EBP1(Thr37/46).

HY-P80786A

	Phospho-eIF4EBP1 (Thr46) Antibody (YA230)(PBS only) EIF4Ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I	WB, IHC-P, IP	Human, Mouse, Rat
	Phospho-eIF4EBP1 (Thr46) Antibody (YA230) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-eIF4EBP1 (Thr46).