1. PI3K/Akt/mTOR
  2. mTOR
  3. (+)-Usnic acid

(+)-Usnic acid 

Cat. No.: HY-N0656A Purity: >99.0%
Handling Instructions

(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity.

For research use only. We do not sell to patients.

(+)-Usnic acid Chemical Structure

(+)-Usnic acid Chemical Structure

CAS No. : 7562-61-0

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10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1].

IC50 & Target[1]

mTORC1

 

mTORC2

 

Molecular Weight

344.32

Formula

C₁₈H₁₆O₇

CAS No.

7562-61-0

SMILES

O=C([[email protected]@]1(C)C(OC2=C(C(C)=O)C(O)=C(C)C(O)=C12)=C3)C(C(C)=O)C3=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References

Purity: >99.0%

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(+)-Usnic acid
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HY-N0656A
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