4-O-Methyl-ascochlorin
4-O-Methyl-ascochlorin (Compound MAC) is a derivative of Ascochlorin (HY-101021). 4-O-Methyl-ascochlorin can selectively induce apoptosis of K562 leukemia cells, cause G1 phase arrest and downregulate c-Myc expression. 4-O-Methyl-ascochlorin can promote the phosphorylation of AMPK and inhibit the phosphorylation of mTOR and its target proteins, including p70S6 K and 4E-BP-1. 4-O-Methyl-ascochlorin can be used for research of leukemia.
For research use only. We do not sell to patients.
- CAS No.: 38561-40-9
- Formula: C24H31ClO4
- Molecular Weight:418.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| C3H 10T1/2 | IC50 |
1.8 μM
Compound: 3
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Concentration required for inhibition of C3H10T1/2 progenitor cell growth
Concentration required for inhibition of C3H10T1/2 progenitor cell growth
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[PMID: 12954063] |
Chemical Information
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CAS No. 38561-40-9
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Molecular Weight 418.95
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Formula C24H31ClO4
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SMILES
C[C@]1([C@H](C(CC[C@H]1C)=O)C)/C=C/C(C)=C/CC2=C(C(Cl)=C(C(C=O)=C2O)C)OC
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Structure Classification
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Initial Source
Ascochyta viciae
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-O-Methyl-ascochlorin Related Classifications
HY-N15121 Related Classifications
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