RMC-4627
Based on 1 Customer Validation
RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.
For research use only. We do not sell to patients.
- Purity: 98.41%
- CAS No.: 2250059-52-8
- Formula: C93H141N11O23
- Molecular Weight:1781.17
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
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CAS No. 2250059-52-8
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Appearance Solid
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Molecular Weight 1781.17
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Formula C93H141N11O23
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Color White to light yellow
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SMILES
NC1=C2C(C3=CC4=CC(O)=CC=C4N3)=NN(C2=NC=N1)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN5C=C(N=N5)CCCCO[C@H]6[C@@H](C[C@@H](CC6)C[C@H]([C@@]7([H])OC([C@@]8([H])N(CCCC8)C(C([C@@]9(O[C@](CC[C@H]9C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C([C@@H]([C@@H](/C(C)=C/[C@H](C(C7)=O)C)O)OC)=O)C)C)OC)O)=O)=O)=O)C)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (56.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5614 mL | 2.8071 mL | 5.6143 mL | 14.0357 mL |
| 5 mM | 0.1123 mL | 0.5614 mL | 1.1229 mL | 2.8071 mL | |
| 10 mM | 0.0561 mL | 0.2807 mL | 0.5614 mL | 1.4036 mL | |
| 15 mM | 0.0374 mL | 0.1871 mL | 0.3743 mL | 0.9357 mL | |
| 20 mM | 0.0281 mL | 0.1404 mL | 0.2807 mL | 0.7018 mL | |
| 25 mM | 0.0225 mL | 0.1123 mL | 0.2246 mL | 0.5614 mL | |
| 30 mM | 0.0187 mL | 0.0936 mL | 0.1871 mL | 0.4679 mL | |
| 40 mM | 0.0140 mL | 0.0702 mL | 0.1404 mL | 0.3509 mL | |
| 50 mM | 0.0112 mL | 0.0561 mL | 0.1123 mL | 0.2807 mL |