1. PI3K/Akt/mTOR
  2. mTOR
  3. mTOR inhibitor-2

mTOR inhibitor-2 

Cat. No.: HY-111370
Handling Instructions

mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates.

For research use only. We do not sell to patients.

mTOR inhibitor-2 Chemical Structure

mTOR inhibitor-2 Chemical Structure

CAS No. : 2219323-96-1

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Description

mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].

IC50 & Target

mTOR

7 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

411.46

Formula

C₂₃H₂₁N₇O

CAS No.

2219323-96-1

SMILES

O=C(N1C2CCN(CC#N)CC2)C=NC3=C1C4=CC(C5=CN=C(N)C=C5)=CC=C4N=C3

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
mTOR inhibitor-2
Cat. No.:
HY-111370
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mTOR inhibitor-2

Cat. No.: HY-111370