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RAB10 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB12 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB13 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB14 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB15 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB17 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB17 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB18 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB18 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB19 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB20 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB20 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB21 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB21 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB23 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB23 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB24 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB24 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB25 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB25 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB26 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB26 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB28 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB28 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB29 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB29 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB30 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB30 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB31 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB31 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB32 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB32 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB34 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB34 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB35 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB35 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB36 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB36 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB37 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB37 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB38 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB38 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB41 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB41 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB42 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB42 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB43 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB43 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB44 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB44 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB11A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB11A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB1A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB22A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB22A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB27A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB27A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB2A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB33A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB33A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB39A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB39A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB3A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB4A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB5A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB5A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB6A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB6A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB7A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB7A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB8A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB8A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB9A Human Pre-designed siRNA Set A contains three designed siRNAs for RAB9A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB11B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB11B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB1B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB27B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB27B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB2B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB33B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB33B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB39B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB39B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB3B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB3C Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB3D Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB3IP Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3IP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB40B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB40B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB40C Human Pre-designed siRNA Set A contains three designed siRNAs for RAB40C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB4B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB4B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB5B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB5B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB5C Human Pre-designed siRNA Set A contains three designed siRNAs for RAB5C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB6B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB6B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB7B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB7B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB8B Human Pre-designed siRNA Set A contains three designed siRNAs for RAB8B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB11FIP1 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB11FIP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB11FIP3 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB11FIP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB11FIP4 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB11FIP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB11FIP5 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB11FIP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB3GAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3GAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB3GAP2 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3GAP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
RAB3IL1 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3IL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
QX77 is a chaperone-mediated autophagy (CMA) activator and upregulates LAMP2A expression in vitro. QX77 induces Rab11 upregulation, rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells . QX77 can impede self-renewal and promote differentiation of ES cells .
BQZ-485 is a a potent GDI2 inhibitor through the interaction with Tyr245. BQZ-485 disrupts the intrinsic GDI2-Rab1A interaction, thereby abolishing vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus and initiating subsequent paraptosis events .
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 values ranging from 16 μM to 120 μM. MLS000532223 prevents GTP binding to several GTPases .
Nexinhib20 is a specific Rab27a-JFC1 interaction inhibitor with a calculated IC50 of 2.6 μM. Nexinhib20 significantly inhibits superoxide anion production. Nexinhib20 efficiently decreases exocytosis of azurophilic granules in neutrophils stimulated with fMLP, GM-CSF or both. Nexinhib20 has a significant anti-inflammatory activity .
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42 .
ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines .
SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor, with an IC50 of 42 nM. SBI-581 promotes TKS5α accumulation at RAB11-positive vesicles. SBI-581 inhibits invadopodia formation. SBI-581 shows reasonable pharmacokinetics in mice using IP injection. SBI-581 shows antitumor activity . SBI-581 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Psoromic acid is a potent and selective RabGGTase (Rab geranylgeranyl transferase) inhibitor with an IC50 value of 1.3 µM. Psoromic acid is an antioxidative agent. Psoromic acid exhibits a competitive type of HMGR inhibition and mixed type of ACE (angiotensin converting enzyme) inhibition .
Asnuciclib (CDKI-73; LS-007) is an orally active and highly efficacious CDK9 inhibitor, with Ki values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. Asnuciclib down-regulates the RNAPII phosphorylation. Asnuciclib is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion .
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
Corticosterone (Standard) is the analytical standard of Corticosterone. This product is intended for research and analytical applications. Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
Psoromic acid is a potent and selective RabGGTase (Rab geranylgeranyl transferase) inhibitor with an IC50 value of 1.3 µM. Psoromic acid is an antioxidative agent. Psoromic acid exhibits a competitive type of HMGR inhibition and mixed type of ACE (angiotensin converting enzyme) inhibition .
Corticosterone (Standard) is the analytical standard of Corticosterone. This product is intended for research and analytical applications. Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
RAB6A protein forms a complex with BICD1 and directly interacts with DYNLRB1 in the GDP-bound state, suggesting a regulatory role in coordinating cellular functions. In the GTP-bound state, RAB6A interacts with VPS13B, suggesting involvement in VPS13B-related pathways. RAB6A Protein, Human (His) is the recombinant human-derived RAB6A protein, expressed by E. coli , with N-His labeled tag. The total length of RAB6A Protein, Human (His) is 208 a.a., with molecular weight of ~26 kDa.
RAB31 protein binds GDP and GTP and participates in processes like protein transport, insulin response, and receptor internalization. It is mainly located in the early endosome, phagocytic vesicle, and trans-Golgi network membrane. RAB31 is also a biomarker for severe acute respiratory syndrome and is broadly expressed in tissues such as the brain, adrenal glands, and 22 others. RAB31 Protein, Human (His) is the recombinant human-derived RAB31 protein, expressed by E. coli , with N-His labeled tag. The total length of RAB31 Protein, Human (His) is 195 a.a., with molecular weight of ~26 kDa.
RAB7A is a dynamic small GTPase that coordinates endolysosomal trafficking by cycling between a GTP-bound state and a GDP-bound state. In its active state, RAB7A interacts with various effectors, affecting endosomal maturation, microtubule directed migration, and endosome-lysosomal trafficking. RAB7A Protein, Rat (His) is the recombinant rat-derived RAB7A protein, expressed by E. coli , with N-His labeled tag. The total length of RAB7A Protein, Rat (His) is 207 a.a., with molecular weight of ~25.7 kDa.
IL5 Protein is a cytokine that plays a critical role in regulating immune responses, particularly in promoting the production and activation of eosinophils. It is involved in modulating allergic and inflammatory processes. Dysregulation of IL5 Protein has been associated with various diseases, including asthma and allergic rhinitis. Targeting IL5 Protein may offer potential therapeutic interventions in these conditions by inhibiting eosinophil activation and reducing inflammation. RAB5C, Human (HEK293, His) is the recombinant human-derived RAB5C, expressed by HEK293, with C-His labeled tag. The total length of RAB5C, Human (HEK293, His) is 216 a.a., with molecular weight of ~25 kDa.
The RAB1B protein is an important small GTPase that regulates intracellular membrane trafficking by coordinating vesicular processes through cycling between GDP and GTP forms. It recruits downstream effectors to achieve vesicle functions, including formation, movement, and fusion. RAB1B Protein, Human (HEK293, Fc) is the recombinant human-derived RAB1B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of RAB1B Protein, Human (HEK293, Fc) is 199 a.a., with molecular weight of ~58 kDa.
RAB27B is a dynamic small GTPase that regulates the late endocytic pathway by cycling between its active GTP-bound and inactive GDP-bound states. In the active state, RAB27B interacts with multiple effectors to coordinate endosomal localization, maturation, and secretion. RAB27B Protein, Human (HEK293) is the recombinant human-derived RAB27B protein, expressed by HEK293 , with tag free. The total length of RAB27B Protein, Human (HEK293) is 214 a.a., with molecular weight of ~27 kDa.
RAB27B is a dynamic small GTPase that regulates the late endocytic pathway by cycling between its active GTP-bound and inactive GDP-bound states. In the active state, RAB27B interacts with multiple effectors to coordinate endosomal localization, maturation, and secretion. RAB27B Protein, Human (HEK293, His) is the recombinant human-derived RAB27B protein, expressed by HEK293 , with N-His labeled tag. The total length of RAB27B Protein, Human (HEK293, His) is 214 a.a., with molecular weight of ~29 kDa.
RAB27B is a dynamic small GTPase that regulates the late endocytic pathway by cycling between its active GTP-bound and inactive GDP-bound states. In the active state, RAB27B interacts with multiple effectors to coordinate endosomal localization, maturation, and secretion. RAB27B Protein, Human (HEK293, Fc) is the recombinant human-derived RAB27B protein, expressed by HEK293 , with N-mFc labeled tag. The total length of RAB27B Protein, Human (HEK293, Fc) is 214 a.a., with molecular weight of ~51 kDa.
RAB11B protein is an important small GTPase in the Rab family, coordinating intracellular membrane transport by regulating vesicle processes. It cycles between GDP and GTP forms, recruiting effectors to control activities such as vesicle formation and movement. RAB11B Protein, Human (HEK293, His) is the recombinant human-derived RAB11B protein, expressed by HEK293 , with N-His labeled tag. The total length of RAB11B Protein, Human (HEK293, His) is 214 a.a., with molecular weight of ~25-30 kDa.
GDI2 protein inhibits the exchange of GDP to GTP in Rab proteins and regulates intracellular membrane transport. GDI2 Protein, Human (P.pastoris, His) is the recombinant human-derived GDI2 protein, expressed by P. pastoris , with N-His labeled tag. The total length of GDI2 Protein, Human (P.pastoris, His) is 445 a.a., with molecular weight of ~52.7 kDa.
MAP4K2 is a serine/threonine protein kinase and an important component of the MAP kinase signal transduction pathway. It acts as a MAPK kinase kinase (MAP4K), activating the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) pathway and, to a lesser extent, the p38 MAPKs pathway. MAP4K2 Protein, Human (sf9, His-GST) is the recombinant human-derived MAP4K2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of MAP4K2 Protein, Human (sf9, His-GST) is 812 a.a., with molecular weight of ~116 kDa.
Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. PTPRC/CD45RAB Protein, Human (529a.a, HEK293, His) is the recombinant human-derived PTPRC/CD45RAB protein, expressed by HEK293 , with C-His labeled tag. The total length of PTPRC/CD45RAB Protein, Human (529a.a, HEK293, His) is 529 a.a., with molecular weight of ~57.4 kDa.
Rab5 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 24 kDa, targeting to Rab5. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse.
RAB7 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 23 kDa, targeting to RAB7. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human, Mouse.
RAB5C Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 23 kDa, targeting to RAB5C. It can be used for WB,IHC-P assays with tag free, in the background of Human.
RAB8A Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 24 kDa, targeting to RAB8A. It can be used for WB assays with tag free, in the background of Human.