1. GPCR/G Protein
  2. Ras
  3. StRIP16

StRIP16 

Cat. No.: HY-136197
Handling Instructions

StRIP16, bioavailable StRIP3 analogue, is a double-stapled peptide which can bind to Rab8a GTPase, with a Kd of 12.7 μM.

For research use only. We do not sell to patients.

StRIP16 Chemical Structure

StRIP16 Chemical Structure

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All Ras Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

StRIP16, bioavailable StRIP3 analogue, is a double-stapled peptide which can bind to Rab8a GTPase, with a Kd of 12.7 μM[1].

IC50 & Target

Kd: 12.7 μM (Rab8a GTPase)[1]

In Vitro

StRIP16 shows selectivity for Rab8 over other Rab-GTPases and does not engage H-Ras or N-Ras (rel. Kd=~10, ~25, ~35, 1.0, ~10, >100, >50, and >100 for Rab1b, Rab5a, Rab6a, Rab8a, Rab9a, Rab11a, H- and N-Ras respectively)[1].

Molecular Weight

2300.65

Formula

C₁₁₆H₁₅₄N₂₄O₂₆

SMILES

CC(C)C[[email protected]](NC([[email protected]](CC1=CN=CN1)NC([[email protected]](CC2=CC=C(O)C=C2)NC([[email protected]]3(C)CCC/C=C/CCC[[email protected]](C(N[[email protected]@H](CCC(N)=O)C(N[[email protected]@H](CC4=CNC5=CC=CC=C45)C(N[[email protected]@H](CC6=CC=CC=C6)C(N3)=O)=O)=O)=O)(C)NC([[email protected]](CCC(O)=O)NC([[email protected]](CC(N)=O)NC([[email protected]@H](NC(C)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)C(N[[email protected]@]7(C)CCC/C=C/CCC[[email protected]](C(N[[email protected]@H](C(C)C)C(N)=O)=O)(C)NC([[email protected]](CC(N)=O)NC([[email protected]](CC8=CC=CC=C8)NC([[email protected]](CC9=CC=CC=C9)NC7=O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

StRIP16StRIP 16StRIP-16RasStRIP3double-stapledRab8aGTPaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
StRIP16
Cat. No.:
HY-136197
Quantity:
MCE Japan Authorized Agent: