1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. StRIP16

StRIP16, bioavailable StRIP3 analogue, is a double-stapled peptide which can bind to Rab8a GTPase, with a Kd of 12.7 μM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

StRIP16

StRIP16 Chemical Structure

CAS No. : 2761279-63-2

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Description

StRIP16, bioavailable StRIP3 analogue, is a double-stapled peptide which can bind to Rab8a GTPase, with a Kd of 12.7 μM[1].

IC50 & Target

Kd: 12.7 μM (Rab8a GTPase)[1]

In Vitro

StRIP16 shows selectivity for Rab8 over other Rab-GTPases and does not engage H-Ras or N-Ras (rel. Kd=~10, ~25, ~35, 1.0, ~10, >100, >50, and >100 for Rab1b, Rab5a, Rab6a, Rab8a, Rab9a, Rab11a, H- and N-Ras respectively)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2300.61

Formula

C116H154N24O26

CAS No.
Sequence

Ac-Asp-Asn-Glu-S5'-Gln-Trp-Phe-S5'-Tyr-His-Leu-S5''-Phe-Phe-Asn-S5''-Val-NH2

Sequence Shortening

Ac-DNE-S5'-QWF-S5'-YHL-S5''-FFN-S5''-V-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
StRIP16
Cat. No.:
HY-136197
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