1. GPCR/G Protein
  2. Ras
  3. MLS-573151

MLS-573151 (Synonyms: MLS000573151)

Cat. No.: HY-113849
Handling Instructions

MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42.

For research use only. We do not sell to patients.

MLS-573151 Chemical Structure

MLS-573151 Chemical Structure

CAS No. : 10179-57-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 110 In-stock
Estimated Time of Arrival: December 31
5 mg USD 100 In-stock
Estimated Time of Arrival: December 31
10 mg USD 170 In-stock
Estimated Time of Arrival: December 31
25 mg USD 350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 950 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
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Description

MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42[1][2].

In Vitro

The fluorescence intensities of phagocytosed beads or bacteria in hemocytes, taken as a measure of phagocytosis efficiency, were markedly reduced in granulocytes treated with MLS-573151 (50 μM; for 15 min) compared to that in the control group. MLS-573151 could effectively inhibit the phagocytic ability of granulocytes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

377.46

Formula

C₂₁H₁₉N₃O₂S

CAS No.

10179-57-4

SMILES

O=S(C1=CC=C(N2N=C(C3=CC=CC=C3)CC2C4=CC=CC=C4)C=C1)(N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

MLS-573151MLS000573151MLS573151MLS 573151MLS 000573151MLS-000573151RasGTPaseCdc42granulocytesInhibitorinhibitorinhibit

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Product Name:
MLS-573151
Cat. No.:
HY-113849
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