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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
SMMC7721
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "SMMC7721" in MCE Product Catalog:
1
1 Cited Publications
Category:
Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Antibacterial Anticancer Disease Research Fields Cancer
Target:
Referencia número: HY-P11308
No. CAS: 1421680-54-7
Referencia número: HY-N7022
No. CAS: 158511-59-2
Target:
Referencia número: HY-N4048
No. CAS: 133453-58-4
Target:
Category:
Alkaloids Piperidine Alkaloids Dicranostigma leptopodum (Maxim.) Fedde Plants Disease Research Fields Papaveraceae Cancer
Target:
Referencia número: HY-N16067
No. CAS: 1442381-95-4
Target:
Referencia número: HY-178918
No. CAS: 1282141-20-1
Target:
Áreas de investigación:
XZA-1 is a 3-hydroxyacyl-coenzyme A dehydrogenase (HADH) activator. XZA-1 increases the intracellular level of acetoacetyl-CoA, which in turn induces acetoacetylation modification of Chromobox Protein Homolog 4 (CBX4) at lysine 106 (K106). XZA-1 exhibits antitumor effects in a xenograft model of human hepatocellular carcinoma SMMC7721 cells overexpressing CBX4. XZA-1 can be used for the study of hepatocellular carcinoma .
Referencia número: HY-N3722
No. CAS: 123497-84-7
Target:
Referencia número: HY-164372
No. CAS: 299173-64-1
Synonyms: 17-DR
17-Demethoxy-reblastatin (17-DR) is an inhibitor for heat shock protein 90 (Hsp90), with an IC50 of 1.82 μM for yeast Hsp90 ATPase. 17-Demethoxy-reblastatin inhibits the proliferation of cancer cell HepG2 and SMMC7721, reduces the colony formation, and induces apoptosis through mitochondria and caspase mediated pathway .
Referencia número: HY-N7022R
No. CAS: 158511-59-2
Category:
Target:
Referencia número: HY-160064
Target:
Áreas de investigación:
SW1-A aptamer sodium is an optimized aptamer based on SW1 aptamer (HY-160063) that specifically targets liver cancer SMMC-7721 cells (Kd: 133.73 nM). SW1-A aptamer maintains strong affinity to liver cancer tissues and cells .
Referencia número: HY-160063
Áreas de investigación:
SW1 aptamer sodium is a high-affinity DNA aptamer (Kd: 123.62 nM) that targets liver cancer SMMC-7721 cells and targets intracellular components within the nucleus. SW1 aptamer sodium can also identify various other types of cancer cells and tissues, serving as an effective molecular probe for clinical cancer diagnosis .
Referencia número: HY-N10876
No. CAS: 863301-69-3
Category:
Target:
Referencia número: HY-N3210
No. CAS: 60048-88-6
Target:
Referencia número: HY-145290
No. CAS: 2968315-02-6
Target:
Áreas de investigación:
CPT-Se3, a selenoproagent of Camptothecin (CPT), shows improved potency in killing cancer cells and inhibiting tumor growth. CPT–Se3 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se3 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells (IC50= 2.19-4.7 μM) .
Referencia número: HY-145291
No. CAS: 2968315-03-7
Target:
Áreas de investigación:
CPT-Se4, a selenoproagent of Camptothecin (CPT), shows improved potency in killing cancer cells and inhibiting tumor growth. CPT-Se4 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se4 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells (IC50= 2.54-6.4 μM) .
Referencia número: HY-N8508
No. CAS: 910292-40-9
Category:
Target:
Referencia número: HY-N17005
No. CAS: 1448534-93-7
Category:
Lycopodiaceae Palhinhaea cernua (L.) Vasc. & Franco Terpenoids Phenols Plants Pentacyclic Triterpenoids
Target:
Referencia número: HY-N9674
No. CAS: 2222285-82-5
Target:
Referencia número: HY-133223
No. CAS: 1616080-84-2
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
