Epimedonin H
Epimedonin H is a selective prenylated 2-phenoxychromone compound with no significant cytotoxicity against five human cancer cell lines, including HL-60 and SMMC-7721 (IC50 > 10 μM). Epimedonin H can be used in potential activity screening studies in the field of natural product chemistry. Epimedonin H can be extracted from the dried aerial parts of Epimedium brevicornum (a plant of the genus Epimedium in the Berberidaceae family).
For research use only. We do not sell to patients.
- CAS No.: 2222285-82-5
- Formula: C20H18O7
- Molecular Weight:370.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI |
50 %
Compound: 3
|
Growth inhibition of human A549 cells at 40 uM after 48 hrs by MTS assay relative to control
Growth inhibition of human A549 cells at 40 uM after 48 hrs by MTS assay relative to control
|
[PMID: 29338226] |
| A549 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human A549 cells after 48 hrs by MTS assay
Cytotoxicity against human A549 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| HL-60 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human HL60 cells after 48 hrs by MTS assay
Cytotoxicity against human HL60 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| MCF7 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| SMMC-7721 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| SW480 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human SW480 cells after 48 hrs by MTS assay
Cytotoxicity against human SW480 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
Chemical Information
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CAS No. 2222285-82-5
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Molecular Weight 370.35
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Formula C20H18O7
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SMILES
CC(C(O)CC1=C2C(C(C=C(O2)OC3=CC=C(C=C3)O)=O)=C(C=C1O)O)=C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)