Epimedonin H
Epimedonin H is a selective prenylated 2-phenoxychromone compound with no significant cytotoxicity against five human cancer cell lines, including HL-60 and SMMC-7721 (IC50 > 10 μM). Epimedonin H can be used in potential activity screening studies in the field of natural product chemistry. Epimedonin H can be extracted from the dried aerial parts of Epimedium brevicornum (a plant of the genus Epimedium in the Berberidaceae family).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2222285-82-5
- Fòrmula: C20H18O7
- Peso molecular:370.35
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI |
50 %
Compound: 3
|
Growth inhibition of human A549 cells at 40 uM after 48 hrs by MTS assay relative to control
Growth inhibition of human A549 cells at 40 uM after 48 hrs by MTS assay relative to control
|
[PMID: 29338226] |
| A549 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human A549 cells after 48 hrs by MTS assay
Cytotoxicity against human A549 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| HL-60 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human HL60 cells after 48 hrs by MTS assay
Cytotoxicity against human HL60 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| MCF7 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| SMMC-7721 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| SW480 | IC50 |
>10 μM
Compound: 3
|
Cytotoxicity against human SW480 cells after 48 hrs by MTS assay
Cytotoxicity against human SW480 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
Chemical Information
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No. CAS 2222285-82-5
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Peso molecular 370.35
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Fòrmula C20H18O7
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SMILES
CC(C(O)CC1=C2C(C(C=C(O2)OC3=CC=C(C=C3)O)=O)=C(C=C1O)O)=C
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)