2. 天然物
  3. Plants
  4. Berberidaceae
  5. Epimedium brevicornu Maxim.

Epimedium brevicornu Maxim.

Epimedium brevicornu Maxim. (36):

製品番号 製品名 CAS 番号 純度 構造式
  • HY-N0014
    Icariin

    イカリイン

    		489-32-7 99.06%
    Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator.
    Icariin
  • HY-N0678
    Icaritin

    Icaritin

    		118525-40-9 99.06%
    Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 µM) and primary CML cells (IC50 of 13.4 µM for CML-CP and 18 µM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis[3.
    Icaritin
  • HY-N0257
    Epimedin A

    Epimedin A

    		110623-72-8 99.43%
    Epimedin A, one of the main flavonoid active components in Herba Epimedii, is orally active. Epimedin A can inhibit osteoclastogenesis, differentiation, and bone resorption. Epimedin A also possesses anti-inflammatory activity. Epimedin A can be used in the research of osteoporosis and inflammatory diseases.
    Epimedin A
  • HY-N0260
    Epmedin C 110642-44-9 99.47%
    Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia.
    Epmedin C
  • HY-N1939
    Icariside I

    Icariside I

    		56725-99-6 99.30%
    Icariside I (GH01) is an orally active metabolite of icalin. Icariside I improves estrogen deficiency-induced osteoporosis by simultaneously regulating osteoblast and osteoclast differentiation. Icariside I promotes ATP (HY-B2176) or Nigericin (HY-127019)-induced mtROS production and NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity. Icariside I does not alter the activation of NLRC4 and AIM2 inflammasomes. Icariside I inhibits breast cancer proliferation, apoptosis, invasion, and metastasis by targeting the IL-6/STAT3 pathway. Icariside I is a kynurenine-AhR pathway inhibitor that alleviates cancer by blocking tumor immune escape.
    Icariside I
  • HY-N8078
    Baohuosu 119730-90-4
    Baohuosu is an extract found in abalone cooking broth. Baohuosu contains soluble polysaccharides, polypeptides, free amino acids, various vitamins and minerals.
    Baohuosu
  • HY-N16922
    3"-O-Desmethylspinorhamnoside 2220243-41-2
    3"-O-Desmethylspinorhamnoside is a natural flavonoid.
    3
  • HY-N9674
    Epimedonin H 2222285-82-5
    Epimedonin H is a selective prenylated 2-phenoxychromone compound with no significant cytotoxicity against five human cancer cell lines, including HL-60 and SMMC-7721 (IC50 > 10 μM). Epimedonin H can be used in potential activity screening studies in the field of natural product chemistry. Epimedonin H can be extracted from the dried aerial parts of Epimedium brevicornum (a plant of the genus Epimedium in the Berberidaceae family).
    Epimedonin H
  • HY-N0259
    Epimedin B

    Epimedin B

    		110623-73-9 99.61%
    Epimedin B, a component extracted from Epimedii Folium, is reported to have antiosteoporotic activity.
    Epimedin B
  • HY-N0258
    Epimedin A1 140147-77-9 99.96%
    Epimedin A1 is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.
    Epimedin A1
  • HY-N0014R
    Icariin (Standard) 489-32-7
    Icariin (Standard) is the analytical standard of Icariin. This product is intended for research and analytical applications. Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator.
    Icariin (Standard)
  • HY-N2626
    Epimedoside A 39012-04-9 99.87%
    Epimedoside A is a flavonoid isolated from the roots of Epimedium wushanense. Epimedoside A exhibits significant antioxidant activity in vitro.
    Epimedoside A
  • HY-N2785
    Desmethylicaritin 28610-31-3 99.77%
    Desmethylicaritin is a phytoestrogenic molecule, has inducible effect on directional differentiation of embryonic stem cells into cardiomyocytes. Desmethylicaritin also suppresses adipogenesis via Wnt/β-catenin signaling pathway.
    Desmethylicaritin
  • HY-N6044
    Isoanhydroicaritin 28610-30-2 99.69%
    Isoanhydroicaritin is a flavonoid isolated from the dried root of S. flavescens.
    Isoanhydroicaritin
  • HY-N0873
    Sagittatoside A 118525-35-2 99.47%
    Sagittatoside A is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii).
    Sagittatoside A
  • HY-N1413
    Noricaritin 5240-95-9 99.04%
    Noricaritin is a flavonoid sourced from roots of Epimedium brevicornu Maxim.
    Noricaritin
  • HY-N0875
    IKarisoside A 55395-07-8 99.44%
    IKarisoside A (Icarisoside-A) is a natural flavonol glycoside and has anti-inflammatory properties.
    IKarisoside A
  • HY-N0874
    Sagittatoside B 118525-36-3 99.0%
    Sagittatoside B is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii).
    Sagittatoside B
  • HY-N4020
    Icariside E5 126176-79-2
    Icariside E5 is a lignan glycoside isolated from the Capsicum annuum. Icariside E5 promotes the proliferation of HUVECs without cytotoxicity. Icariside E5 has antioxidant properties.
    Icariside E5
  • HY-N2289
    2''-O-Rhamnosylicariside II 135293-13-9 98.85%
    2''-O-Rhamnosylicariside II is a flavonoid glycoside compound and might be beneficial for improving postmenopausal osteoporosis.
    2''-O-Rhamnosylicariside II