1. Saccharides and Glycosides
  2. Icariside E5

Icariside E5 

Cat. No.: HY-N4020
Handling Instructions

Icariside E5 is a lignan glycoside isolated from the Albiziae Cortex. Icariside E5 promotes the proliferation of HUVECs without cytotoxicity. Icariside E5 has antioxidant properties.

For research use only. We do not sell to patients.

Icariside E5 Chemical Structure

Icariside E5 Chemical Structure

CAS No. : 126176-79-2

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Description

Icariside E5 is a lignan glycoside isolated from the Albiziae Cortex. Icariside E5 promotes the proliferation of HUVECs without cytotoxicity. Icariside E5 has antioxidant properties[1][2].

In Vitro

Icariside E5 (5, 10, 20, 40 µM; for 48 h) slightly promotes the proliferation of human umbilical vein endothelial cells (HUVECs). Icariside E5 does not have the pharmacological effect of scavenging ROS[1].
Icariside E neither induces an increase in the intracellular levels of reactive oxygen species nor affects the mitochondria permeability transition, and it does not signal through the vanilloid receptor type 1. It protects Jurkat cells from apoptosis induced by the oxidative stress mediated by serum withdrawal[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

522.54

Formula

C₂₆H₃₄O₁₁

CAS No.

126176-79-2

SMILES

OC[[email protected]@H](C1=C(C(OC)=CC(/C=C/CO)=C1)O[[email protected]@H]([[email protected]@H]([[email protected]]2O)O)O[[email protected]@H]([[email protected]]2O)CO)CC(C=C3)=CC(OC)=C3O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Icariside E5
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