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  4. Papaveraceae Cancer Piperidine Alkaloids
  5. Dicranostigma leptopodum (Maxim.) Fedde
  6. Corytuberine

Corytuberine is an aporphine alkaloid found in Dicranostigma leptopodum. Corytuberine displays cytotoxicity against SMMC-7721 tumor cells.

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Corytuberine

Corytuberine Chemical Structure

CAS No. : 517-56-6

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Based on 1 publication(s) in Google Scholar

Corytuberine Related Antibodies

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Description

Corytuberine is an aporphine alkaloid found in Dicranostigma leptopodum. Corytuberine displays cytotoxicity against SMMC-7721 tumor cells[1].

Cellular Effect
Cell Line Type Value Description References
B-cell IC50
21.3 μM
Compound: 12
Inhibition of LPS-induced BALB/c mouse B cell proliferation
Inhibition of LPS-induced BALB/c mouse B cell proliferation
[PMID: 17081761]
HeLa IC50
> 200 μM
Compound: 3
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
[PMID: 29103873]
HepG2 IC50
> 200 μM
Compound: 3
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
[PMID: 29103873]
MGC-803 IC50
> 200 μM
Compound: 3
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
[PMID: 29103873]
T-cell IC50
23.2 μM
Compound: 12
Inhibition of ConA-induced BALB/c mouse T cell proliferation
Inhibition of ConA-induced BALB/c mouse T cell proliferation
[PMID: 17081761]
Molecular Weight

327.37

Formula

C19H21NO4
CAS No.
Appearance

Solid

SMILES

OC1=C2C3=C(C=C1OC)CCN(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C24
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Corytuberine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Corytuberine517-56-6OthersInhibitorinhibitorinhibit

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