2. Natural Products
  3. Disease Research Fields Plants Terpenoids
  4. Cancer other families Triterpenes
  5. Eclalbasaponin I

Eclalbasaponin I is isolated from Eclipta prostrata L with antitumor activity. Eclalbasaponin I inhibits the proliferation of hepatoma cell smmc-7721 with an IC50 value of 111.1703 μg/ml.

For research use only. We do not sell to patients.

Eclalbasaponin I Chemical Structure

Eclalbasaponin I Chemical Structure

CAS No. : 158511-59-2

Size Price Stock Quantity
1 mg USD 109 In-stock
5 mg USD 230 In-stock
10 mg USD 380 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Eclalbasaponin I Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Eclalbasaponin I is isolated from Eclipta prostrata L with antitumor activity. Eclalbasaponin I inhibits the proliferation of hepatoma cell smmc-7721 with an IC50 value of 111.1703 μg/ml[1].

IC50 & Target

IC50: 111.1703 μg/ml (smmc-7721 cells)
Molecular Weight

796.98

Formula

C42H68O14
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@H]1OC([C@]23[C@](CC(C)(C)CC3)([H])C4=CC[C@@]([C@@]5([C@@](C(C)([C@@H](O[C@]6([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)CO)CC5)C)([H])CC7)C)([H])[C@]7(C)[C@]4(C)C[C@H]2O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (125.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2547 mL 6.2737 mL 12.5474 mL
5 mM 0.2509 mL 1.2547 mL 2.5095 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2547 mL 6.2737 mL 12.5474 mL 31.3684 mL
5 mM 0.2509 mL 1.2547 mL 2.5095 mL 6.2737 mL
10 mM 0.1255 mL 0.6274 mL 1.2547 mL 3.1368 mL
15 mM 0.0836 mL 0.4182 mL 0.8365 mL 2.0912 mL
20 mM 0.0627 mL 0.3137 mL 0.6274 mL 1.5684 mL
25 mM 0.0502 mL 0.2509 mL 0.5019 mL 1.2547 mL
30 mM 0.0418 mL 0.2091 mL 0.4182 mL 1.0456 mL
40 mM 0.0314 mL 0.1568 mL 0.3137 mL 0.7842 mL
50 mM 0.0251 mL 0.1255 mL 0.2509 mL 0.6274 mL
60 mM 0.0209 mL 0.1046 mL 0.2091 mL 0.5228 mL
80 mM 0.0157 mL 0.0784 mL 0.1568 mL 0.3921 mL
100 mM 0.0125 mL 0.0627 mL 0.1255 mL 0.3137 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eclalbasaponin I158511-59-2OthersInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Eclalbasaponin I
Cat. No.:
HY-N7022
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.