CPT-Se3
CPT-Se3, a selenoproagent of Camptothecin (CPT), shows improved potency in killing cancer cells and inhibiting tumor growth. CPT–Se3 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se3 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells (IC50= 2.19-4.7 μM).
For research use only. We do not sell to patients.
- CAS No.: 2968315-02-6
- Formula: C24H20N2O6Se2
- Molecular Weight:590.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Chemical Information
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CAS No. 2968315-02-6
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Molecular Weight 590.35
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Formula C24H20N2O6Se2
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SMILES
O=C(O[C@]1(C2=C(COC1=O)C(N(C3=C2)CC4=C3N=C5C(C=CC=C5)=C4)=O)CC)OC6C[Se][Se]C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CPT-Se3 Related Classifications
HY-145290 Related Classifications
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