2. Natural Products
  3. Plants Alkaloids
  4. Apocynaceae Indole Alkaloids
  5. Alstonia rostrata C. E. C. Fischer
  6. Nb-Demethylechitamine

Nb-Demethylechitamine is an alkaloid isolated from the methanol extract of Alstonia rostrata twigs. Nb-Demethylechitamine has in vitro cytotoxic activity against several human cancer cell lines, including human myeloid leukemia HL-60, liver cancer SMMC-7721, lung cancer A-549, breast cancer MCF-7, and colon cancer SW480 cells.

For research use only. We do not sell to patients.

Nb-Demethylechitamine Chemical Structure

Nb-Demethylechitamine Chemical Structure

CAS No. : 60048-88-6

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Nb-Demethylechitamine Related Antibodies

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Description

Nb-Demethylechitamine is an alkaloid isolated from the methanol extract of Alstonia rostrata twigs. Nb-Demethylechitamine has in vitro cytotoxic activity against several human cancer cell lines, including human myeloid leukemia HL-60, liver cancer SMMC-7721, lung cancer A-549, breast cancer MCF-7, and colon cancer SW480 cells[1].

Molecular Weight

370.44

Formula

C21H26N2O4
CAS No.
SMILES

C/C=C(C1)\[C@@H]2C[C@@H](O)[C@@]3([N@@]1CC4)[C@]4(C2(CO)C(OC)=O)C5=C(N3)C=CC=C5
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nb-Demethylechitamine60048-88-6OthersAlstonia rostrataApocynaceaemonoterpene indole alkaloidhuman myeloid leukaemiaHL-60hepatocellular carcinomaSMMC-7721lung cancerA-549breast cancerMCF-7colon cancerSW480Inhibitorinhibitorinhibit

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