72 Results for "

L 44-0

" in MedChemExpress (MCE) Product Catalog:
Products (72)

72 Results for "L 44-0" in MCE Product Catalog:

Cat. No.: HY-19013
CAS No.: 95240-93-0
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

L44-0 is a nicotinic acid derivative. L44-0 reduces atherosclerotic lesions and decreases vascular norepinephrine levels in the renal arteries, femoral arteries, and veins in a New Zealand white rabbit model of atherosclerosis. L44-0 can be used in research on cardiovascular and cerebrovascular diseases such as atherosclerosis .
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26
26 Publications Verification
Cat. No.: HY-D0080
CAS No.: 74515-25-6
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase (Ex/Em = 370/440-490 nm).
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11
11 Cited Publications
Cat. No.: HY-115640
CAS No.: 1513848-14-0
Purity:  95.02%
Target:  

TrxR

Research Areas:  

Others

TRFS-green is a highly selective off−on fluorescent probe for imaging selenoprotein thioredoxin reductase (TrxR) in living cells. TRFS-green has the maximum absorbance at around 373 nm. After it is activated by TrxR, the maximum absorbance shifts to around 440 nm .
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10
10 Cited Publications
Cat. No.: HY-103482
CAS No.: 315705-75-0
Purity:  99.80%
Target:  

MMP

Research Areas:  

Cancer

JNJ0966 is a highly selective MMP-9 zymogen inhibitor with an IC50 of 440 nM.
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10
10 Cited Publications
Cat. No.: HY-101883A
BCECF Acetoxymethyl ester is a cell membrane permeable compound widely-used as a fluorescent indicator for intracellular pH. BCECF Acetoxymethyl ester could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm .
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9
9 Cited Publications
Cat. No.: HY-18681
CAS No.: 1446321-46-5
Synonyms: GBT 440
Target:  

Hemoglobin

Research Areas:  

Cardiovascular Disease

Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment .
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4
4 Cited Publications
Cat. No.: HY-101441
CAS No.: 489416-12-8
Purity:  99.93%
Target:  

Arenavirus

Research Areas:  

Infection

ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
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4
4 Cited Publications
Cat. No.: HY-101441A
CAS No.: 2320274-72-2
Purity:  98.76%
Target:  

Arenavirus

Research Areas:  

Infection

ST-193 hydrochloride is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
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3
3 Cited Publications
Cat. No.: HY-101882
CAS No.: 85138-49-4
Purity:  ≥94.0%
Synonyms: 2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein
BCECF is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
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3
3 Cited Publications
Cat. No.: HY-10571
CAS No.: 136817-59-9
Purity:  99.70%
Synonyms: U 90152; BHAP-U 90152
Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine selectively inhibits HIV-1 reverse transcriptase (RT) (IC50=0.26 μM) over DNA polymerase α (IC50=440 μM) and polymerase δ (IC50>550 μM). Delavirdine is an inhibitor of HIV-1 replication and can can be used for the study of AIDs .
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3
3 Cited Publications
Cat. No.: HY-10571A
CAS No.: 147221-93-0
Purity:  99.82%
Synonyms: U 90152 mesylate; BHAP-U 90152 mesylate
Research Areas:  

Infection

Delavirdine (U 90152) mesylate is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine mesylate selectively inhibits HIV-1 reverse transcriptase (RT) (IC50=0.26 μM) over DNA polymerase α (IC50=440 μM) and polymerase δ (IC50>550 μM). Delavirdine mesylate is an inhibitor of HIV-1 replication and can can be used for the study of AIDs .
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2
2 Cited Publications
Cat. No.: HY-D1265
CAS No.: 2929446-76-2
Synonyms: HClO-green
EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells .
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1
1 Cited Publications
Cat. No.: HY-D1445
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) .
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1
1 Cited Publications
Cat. No.: HY-152174
CAS No.: 2075787-77-6
Purity:  99.46%
Target:  

HDAC

Research Areas:  

Cancer

HDAC-IN-52 is a pyridine-containing HDAC inhibitor, with IC50s of 0.189, 0.227, 0.440 and 0.446 μM for HDAC1, HDAC2, HDAC3, and HDAC10, respectively. HDAC-IN-52 can be used for the research of cancer .
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Cat. No.: HY-D0073
CAS No.: 771-97-1
2,3-Diaminonaphthalene is a fluorescent reagent used to detect selenium and nitric oxide (NO). 2,3-Diaminonaphthalene binds to selenium to form pyrazolene selenol, with excitation/emission maxima at 365 nm and 525 nm, respectively. 2,3-Diaminonaphthalene binds to NO2− to form the fluorescent product, 1-(H)-napthotriazole, with excitation/emission maxima at 360 nm and 440 nm, respectively .
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Cat. No.: HY-D0025
CAS No.: 106562-32-7
7-Amino-4-methylcoumarin-3-acetic acid (AMCA) serves as the parent structure of coumarin-based blue fluorescent dyes, and its activated form AMCA-NHS can directly conjugate with proteins (Ex/Em ≈ 350/440-460).
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Cat. No.: HY-D0026
CAS No.: 113721-87-2
Synonyms: 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester
AMCA,SE (7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester) is a bright blue fluorescent dye. AMCA,SE reacts with amino groups and is excited by ultraviolet light. AMCA,SE can be used for amine reactive labeling (Ex/Em = 354/440 nm) .
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Cat. No.: HY-P2179
CAS No.: 150956-92-6
Target:  

Fluorescent Dye MMP

Research Areas:  

Others

MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm
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Cat. No.: HY-135070
CAS No.: 929903-87-7
Synonyms: Ac-Arg-Leu-Arg-AMC
Target:  

Proteasome

Research Areas:  

Others

Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
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Cat. No.: HY-112267
CAS No.: 1897384-89-2
Purity:  99.60%
Synonyms: VX-440
Target:  

CFTR Autophagy

Research Areas:  

Inflammation/Immunology

Olacaftor (VX-440) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator extracted from patent US9782408.
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