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  3. Fluorescent Dye
  4. Msr-blue

Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm).

For research use only. We do not sell to patients.

Msr-blue

Msr-blue Chemical Structure

CAS No. : 2966537-39-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 mg In-stock
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Based on 1 publication(s) in Google Scholar

Msr-blue Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm)[1].

In Vitro

Msr-blue is emited blue fluorescence after activation by methionine sulfoxide reductase A (Msr A). Msr-blue responded to Msr A in both a time- and dose-dependent manner, and more than a 100-fold increase in the emission is observed. Msr-blue is converted to its corresponding sulfide under catalysis by either the purified Msr A or a cell lysate[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Msr-blue Related Antibodies
Molecular Weight

222.26

Formula

C11H10O3S
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

CC(C1=CC=C(C=C1O2)S(C)=O)=CC2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (112.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4992 mL 22.4962 mL 44.9924 mL
5 mM 0.8998 mL 4.4992 mL 8.9985 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.38%

SDS (252 KB)

COA (249 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4992 mL 22.4962 mL 44.9924 mL 112.4809 mL
5 mM 0.8998 mL 4.4992 mL 8.9985 mL 22.4962 mL
10 mM 0.4499 mL 2.2496 mL 4.4992 mL 11.2481 mL
15 mM 0.2999 mL 1.4997 mL 2.9995 mL 7.4987 mL
20 mM 0.2250 mL 1.1248 mL 2.2496 mL 5.6240 mL
25 mM 0.1800 mL 0.8998 mL 1.7997 mL 4.4992 mL
30 mM 0.1500 mL 0.7499 mL 1.4997 mL 3.7494 mL
40 mM 0.1125 mL 0.5624 mL 1.1248 mL 2.8120 mL
50 mM 0.0900 mL 0.4499 mL 0.8998 mL 2.2496 mL
60 mM 0.0750 mL 0.3749 mL 0.7499 mL 1.8747 mL
80 mM 0.0562 mL 0.2812 mL 0.5624 mL 1.4060 mL
100 mM 0.0450 mL 0.2250 mL 0.4499 mL 1.1248 mL
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Msr-blue Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Msr-blue2966537-39-1Fluorescent DyefluorescentmethioninesulfoxidereductaselivecellssulfideMsrAInhibitorinhibitorinhibit

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