Msr-blue
Based on 1 Customer Validation
Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm).
For research use only. We do not sell to patients.
- Purity: 99.38%
- CAS No.: 2966537-39-1
- Formula: C11H10O3S
- Molecular Weight:222.26
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Msr-blue is emited blue fluorescence after activation by methionine sulfoxide reductase A (Msr A). Msr-blue responded to Msr A in both a time- and dose-dependent manner, and more than a 100-fold increase in the emission is observed. Msr-blue is converted to its corresponding sulfide under catalysis by either the purified Msr A or a cell lysate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2966537-39-1
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Appearance Solid
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Molecular Weight 222.26
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Formula C11H10O3S
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Color White to yellow
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SMILES
CC(C1=CC=C(C=C1O2)S(C)=O)=CC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 25 mg/mL (112.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4992 mL | 22.4962 mL | 44.9924 mL | 112.4809 mL |
| 5 mM | 0.8998 mL | 4.4992 mL | 8.9985 mL | 22.4962 mL | |
| 10 mM | 0.4499 mL | 2.2496 mL | 4.4992 mL | 11.2481 mL | |
| 15 mM | 0.2999 mL | 1.4997 mL | 2.9995 mL | 7.4987 mL | |
| 20 mM | 0.2250 mL | 1.1248 mL | 2.2496 mL | 5.6240 mL | |
| 25 mM | 0.1800 mL | 0.8998 mL | 1.7997 mL | 4.4992 mL | |
| 30 mM | 0.1500 mL | 0.7499 mL | 1.4997 mL | 3.7494 mL | |
| 40 mM | 0.1125 mL | 0.5624 mL | 1.1248 mL | 2.8120 mL | |
| 50 mM | 0.0900 mL | 0.4499 mL | 0.8998 mL | 2.2496 mL | |
| 60 mM | 0.0750 mL | 0.3749 mL | 0.7499 mL | 1.8747 mL | |
| 80 mM | 0.0562 mL | 0.2812 mL | 0.5624 mL | 1.4060 mL | |
| 100 mM | 0.0450 mL | 0.2250 mL | 0.4499 mL | 1.1248 mL |
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