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Cat. No.: HY-112074A

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Tiamenidine hydrochloride

(Synonyms: HOE 440 hydrochloride)

Tiamenidine hydrochloride (HOE 440 hydrochloride) is a centrally acting α1-adrenergic receptor antagonist with hypotensive activity. Tiamenidine hydrochloride regulates blood pressure levels by binding to α1 receptors. Tiamenidine hydrochloride can be used in the study of hypertension.

For research use only. We do not sell to patients.

CAS No.: 51274-83-0
Formula: C₈H₁₁Cl₂N₃S
Molecular Weight:252.16

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Tiamenidine hydrochloride Chemical Structure

CAS No.: 51274-83-0

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Biological Activity

Description

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 51274-83-0
Molecular Weight 252.16
Formula C₈H₁₁Cl₂N₃S
SMILES

ClC1=C(NC2=NCCN2)C(C)=CS1.Cl
Synonyms

HOE 440 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. D M Roden, et al. Electrophysiologic and hemodynamic effects of chronic oral therapy with the alpha 2-agonists clonidine and tiamenidine in hypertensive volunteers. Clin Pharmacol Ther. 1988 Jun;43(6):648-54. [Content Brief]

[2]. Quantitative determination of tiamenidine hydrochloride in human serum using gas chromatography mass spectrometry

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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References

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Tiamenidine hydrochloride

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Tiamenidine hydrochloride Related Classifications

HY-112074A Related Classifications