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GBT 440 (Synonyms: Voxelotor)

Cat. No.: HY-18681 Purity: 99.96%
Handling Instructions

GBT 440 is a modulator of sickle hemoglobin (HbS), extracted from patent WO2015116061A1, compound 5, which can be used in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.

For research use only. We do not sell to patients.

GBT 440 Chemical Structure

GBT 440 Chemical Structure

CAS No. : 1446321-46-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 110 In-stock
Estimated Time of Arrival: December 31
5 mg USD 100 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
50 mg USD 490 In-stock
Estimated Time of Arrival: December 31
100 mg USD 750 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

GBT 440 is a modulator of sickle hemoglobin (HbS), extracted from patent WO2015116061A1, compound 5, which can be used in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (370.51 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9641 mL 14.8205 mL 29.6410 mL
5 mM 0.5928 mL 2.9641 mL 5.9282 mL
10 mM 0.2964 mL 1.4821 mL 2.9641 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

337.37

Formula

C₁₉H₁₉N₃O₃

CAS No.

1446321-46-5

SMILES

OC1=CC=CC(OCC2=C(C3=CC=NN3C(C)C)N=CC=C2)=C1C=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.96%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
GBT 440
Cat. No.:
HY-18681
Quantity:

GBT 440

Cat. No.: HY-18681