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  4. EtS-DMAB

EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells.

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EtS-DMAB

EtS-DMAB Chemical Structure

CAS No. : 2929446-76-2

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Based on 2 publication(s) in Google Scholar

EtS-DMAB Related Antibodies

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Description

EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells[1].

In Vitro

EtS-DMAB can selectively detect hypochlorous acid (HOCl) over other reactive oxygen species in aqueous solution with a large stokes shift (～170 nm). It turns out that oxidation of the thioether to the corresponding sulfoxide accounts for the turn-on fluorescence[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EtS-DMAB Related Antibodies
Molecular Weight

223.29

Formula

C10H13N3OS
CAS No.
Appearance

Viscous Liquid

Color

Brown to reddish brown

Emission (Em)

610
Excitation (Ex)

440
SMILES

CN(C1=CC=C(C2=NON=C21)SCC)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (223.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4785 mL 22.3924 mL 44.7848 mL
5 mM 0.8957 mL 4.4785 mL 8.9570 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4785 mL 22.3924 mL 44.7848 mL 111.9620 mL
5 mM 0.8957 mL 4.4785 mL 8.9570 mL 22.3924 mL
10 mM 0.4478 mL 2.2392 mL 4.4785 mL 11.1962 mL
15 mM 0.2986 mL 1.4928 mL 2.9857 mL 7.4641 mL
20 mM 0.2239 mL 1.1196 mL 2.2392 mL 5.5981 mL
25 mM 0.1791 mL 0.8957 mL 1.7914 mL 4.4785 mL
30 mM 0.1493 mL 0.7464 mL 1.4928 mL 3.7321 mL
40 mM 0.1120 mL 0.5598 mL 1.1196 mL 2.7991 mL
50 mM 0.0896 mL 0.4478 mL 0.8957 mL 2.2392 mL
60 mM 0.0746 mL 0.3732 mL 0.7464 mL 1.8660 mL
80 mM 0.0560 mL 0.2799 mL 0.5598 mL 1.3995 mL
100 mM 0.0448 mL 0.2239 mL 0.4478 mL 1.1196 mL
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EtS-DMAB Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EtS-DMAB2929446-76-2HClO-greenFluorescent DyeHOClfluorescentprobelivecellssulfoxideInhibitorinhibitorinhibit

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