Search Result
Results for "
Linear
" in MedChemExpress (MCE) Product Catalog:
8
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N5110
-
(-)-Marmesinin; Ammijin
|
Others
|
Neurological Disease
|
Marmesinin ((-)-Marmesinin), a natural coumarin, is a biosynthetic precursor of psoralen and linear furanocoumarins. Marmesinin exhibits significant neuroprotective activities against glutamate-induced toxicity .
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-
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- HY-W250110B
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PEI (Linear, average Mn 2100, PDI<1.3)
|
Liposome
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Cancer
|
Polyethylenimine (PEI) (linear, average Mn 2100, PDI<1.3), a cationic polymer, is a non-viral gene delivery vector, especially for oligonucleotide delivery .
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-
-
- HY-157438A
-
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Others
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Metabolic Disease
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pppApA sodium is a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP. pppApA sodium is formed by conjugation between two molecules of ATP .
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-
-
- HY-157438
-
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Others
|
Metabolic Disease
|
pppApA is a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP. pppApA is formed by conjugation between two molecules of ATP .
|
-
-
- HY-N3997
-
|
Ser/Thr Protease
|
Infection
Metabolic Disease
Cancer
|
Nostosin G is a unique example of a linear peptide containing three subunits, 4-hydroxyphenyllactic acid (Hpla), homotyrosine (Hty), and argininal. Nostosin G has potent trypsin inhibitory property with an IC50 value of 0.1 μM .
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-
-
- HY-P0290
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GRGDSP
4 Publications Verification
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Integrin
|
Cancer
|
GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
|
-
-
- HY-P1539
-
-
-
- HY-N7701B
-
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Others
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Infection
|
L-Tetraguluronic acid is a linear polysaccharide copolymer composed of four L-guluronic acid (G) .
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-
-
- HY-N7701C
-
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Others
|
Infection
|
L-Pentaguluronic acid is a linear polysaccharide copolymer composed of four L-guluronic acid (G) .
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-
-
- HY-N7701D
-
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Others
|
Infection
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L-Hexaguluronic acid is a linear polysaccharide copolymer composed of six L-guluronic acid (G) .
|
-
-
- HY-N8975
-
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Others
|
Cancer
|
Antitumor agent-137 (Compound M12) is a linear diarylheptanoid compound with antitumor activity .
|
-
-
- HY-N2176A
-
|
Cholinesterase (ChE)
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Others
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(±)-Marmesin is a good precursor of the linear furanocoumarins. (±)-Marmesin derivatives have high degree of acetylcholinesterase inhibitory property .
|
-
-
- HY-P2318
-
|
Fungal
|
|
Bac2A TFA is an antimicrobial and immunomodulatory peptide. Bac2A TFA is a linear variant of bactenecin and is very effective against fungal pathogens.
|
-
-
- HY-34465
-
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Others
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Others
|
5-Methyl-2-thiophenecarboxaldehyde acts as a candidate to microscopic third order non-linear optical (NLO) material .
|
-
-
- HY-101916
-
-
-
- HY-P1203
-
-
-
- HY-P1203A
-
-
-
- HY-145485
-
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Biochemical Assay Reagents
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Others
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HS-PEG-SH (MW 3400), a linear homobifunctional PEG, is a cross-linker. HS-PEG-SH can be used for drug delivery and preparation of PEG hydrogels .
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-
-
- HY-N10373
-
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Others
|
Others
|
Caffeoyl alcohol is a monomer constituting Catechyl lignin. Catechyl lignin is a linear homopolymer of caffeyl alcohol, a natural source of carbon fiber and high-value chemicals .
|
-
-
- HY-D1005H
-
PEG-PPG-PEG, 8400(Average Mn)
|
Fluorescent Dye
Biochemical Assay Reagents
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Others
|
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models .
|
-
-
- HY-P1539A
-
-
-
- HY-D1478
-
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Fluorescent Dye
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Others
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Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .
|
-
-
- HY-108455
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PALDA
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Others
|
Neurological Disease
|
N-Palmitoyl dopamine (PALDA) is a endogenous, long-chain, linear fatty acid dopamide, which is inactive on TRPV1. N-Palmitoyl dopamine displays 'entourage' effects on endovanilloids N-arachidonoyl-dopamine (NADA) and anandamide .
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-
-
- HY-160042
-
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Others
|
Cancer
|
AFP aptamer sodium is an aptamer that specifically targets the liver cancer biomarker alpha-fetoprotein (AFP). AFP aptamer sodium can be used as a recognition molecule for AFP, with a linear detection range of 12.5-800 ng/mL .
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-
-
- HY-P1807
-
|
Histamine Receptor
|
Inflammation/Immunology
|
Mast Cell Degranulating Peptide HR-2, a 14-membered linear peptide isolated from the venom of the giant hornet Vespa orientalis, is capable of degranulating mast cells and thus initiating histamine release .
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-
-
- HY-W190796
-
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Others
|
Others
|
Mal-PEG3-NH2 is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 is a useful crosslinking reagent with a PEG spacer .
|
-
-
- HY-P1714
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FE 203799
|
GLP Receptor
|
Metabolic Disease
|
Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
|
-
-
- HY-N7701
-
|
Fungal
|
Infection
|
L-Diguluronic acid is a linear polysaccharide copolymer composed of two L-guluronic acid (G) and can be used to from Alginate . Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of antifungal agents delivery carries .
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-
-
- HY-132177A
-
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Others
|
Metabolic Disease
|
α1-2 Fucosidase (EC 3.2.1.51) is a highly specific exoglycosidase that catalyzes the hydrolysis of linear α1-2 linked fucose residues from oligosaccharides .
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-
-
- HY-30152
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-
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- HY-N7701A
-
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Fungal
|
Infection
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L-Triguluronic acid is a linear polysaccharide copolymer composed of three L-guluronic acid (G) and can be used to from Alginate . Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of anti-fungal agents delivery carries .
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-
-
- HY-122881
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JTP-0819958
|
IKK
|
Cancer
|
HOIPIN-1 (JTP-0819958) is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM . HOIPIN-1 suppress LUBAC-mediated NF-kB activation in vitro .
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-
-
- HY-D1005A
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PEG-PPG-PEG, 8800 (Average Mn)
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models. Poloxamer 188 can be used for drug delivery .
|
-
-
- HY-P4115
-
|
FABP
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Cancer
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CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles .
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-
-
- HY-125870
-
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
Gellan gum is a linear microbial exopolysaccharide that can be used as a cell scaffold for both soft tissue and load bearing applications. Gellan gum has many advantages such as biocompatibility, biodegradability, nontoxic in nature, and physical stability in the presence of cations .
|
-
-
- HY-P1714A
-
FE 203799 TFA
|
GLP Receptor
|
Metabolic Disease
|
Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
|
-
-
- HY-N7701E
-
|
Fungal
|
Infection
|
L-Diguluronic acid disodium is a linear polysaccharide copolymer composed of two L-guluronic acid. L-Diguluronic acid disodium can be used to form Alginate. L-Diguluronic acid disodium is a generic name of unbranched polyanionic polysaccharides and it can be used for the research of antifungal agents delivery carries .
|
-
-
- HY-100616
-
cis-1-Aminocyclobutane-1,3-dicarboxylic acid
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Others
|
Neurological Disease
|
cis-ACBD is a potent and selective inhibitor of the high-affinity, Na +-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate .
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-
-
- HY-118090
-
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Others
|
Others
|
L-γ-Glutamyl-L-glutamic acid is the isomer of D-γ-Glutamyl-D-glutamic acid (HY-118090A), and can be used as an experimental control. D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain .
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-
-
- HY-P3465
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Myrcludex B
|
HBV
|
Infection
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Bulevirtide (Myrcludex B) is a NTCP inhibitor, a linear lipopeptide of 47 amino acids. Bulevirtide inhibits HBV and HDV entry into liver cells, blocks HBV infection in hepatocytes, and participates in HBV transcriptional suppression. Bulevirtide can be used in HDV infection and compensated cirrhosis research .
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-
-
- HY-W190796A
-
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PROTAC Linkers
|
Cancer
|
Mal-PEG3-NH2 TFA is a linear heterobifunctional PEG crosslinker with Maleimide (HY-W007324) and amine. Mal-PEG3-NH2 TFA is a non-degradable (non-cleavable) PROTAC linker .
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-
-
- HY-N10109A
-
|
SARS-CoV
Parasite
Cathepsin
|
Infection
|
Gallinamide A TFA is a linearly depositing peptide and a potent inhibitor of cathepsin L (CatL) (IC50: 17.6 pM). Gallinamide A TFA inhibits SARS-CoV-2 infection by inhibiting CatL (EC50: 28 nM). Gallinamide A TFA also inhibits Plasmodium falciparum (IC50: 50 nM) .
|
-
-
- HY-P1019A
-
|
Endothelin Receptor
|
Cardiovascular Disease
Endocrinology
|
[Ala1,3,11,15]-Endothelin (53-63) (TFA) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) (TFA) has selectivity for ET B with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) (TFA) can be used for the research of vasoconstriction .
|
-
-
- HY-P1019
-
|
Endothelin Receptor
|
Cardiovascular Disease
Endocrinology
|
[Ala1,3,11,15]-Endothelin (53-63) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) has selectivity for ET B with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) can be used for the research of vasoconstriction
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-
-
- HY-P4896
-
|
Integrin
|
Cancer
|
FITC-Ahx Gly Arg Gly Asp Ser Pro is a GRGDSP (HY-P0290) coupled to FITC. GRGDSP is an integrin inhibitor that can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis .
|
-
-
- HY-B2144A
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Deacetylated chitin (MW 150000); Poly(D-glucosamine) (MW 150000)
|
Bacterial
Fungal
|
Infection
Cancer
|
Chitosan (MW 150000) (Deacetylated chitin (MW 150000)) is a polycationic linear polysaccharide derived from chitin with the molecular weight of 150000. Chitosan is an versatile biomaterial because of its non-toxicity, low allergenicity, biocompatibility and biodegradability. Chitosan also has antitumor, antibacterial, antifungal, and antioxidant activities .
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-
-
- HY-B2144B
-
Deacetylated chitin (MW 30000); Poly(D-glucosamine) (MW 30000)
|
Bacterial
Fungal
|
Infection
Cancer
|
Chitosan (MW 30000) (Deacetylated chitin (MW 30000)) is a polycationic linear polysaccharide derived from chitin with the molecular weight of 30000. Chitosan is an versatile biomaterial because of its non-toxicity, low allergenicity, biocompatibility and biodegradability. Chitosan also has antitumor, antibacterial, antifungal, and antioxidant activities .
|
-
-
- HY-W250580
-
|
Biochemical Assay Reagents
|
Others
|
Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products .
|
-
-
- HY-101647
-
RP 60475
|
Topoisomerase
|
Cancer
|
Intoplicine (RP 60475), an antitumor derivative in the 7H-benzo[e]pyrido[4,3-b]indole series, is a DNA topoisomerase I and II inhibitor. Intoplicine strongly binds DNA (KA = 2 x 10 5 /M) and thereby increases the length of linear DNA .
|
-
-
- HY-101647A
-
RP 60475 dimesylate
|
Topoisomerase
|
Cancer
|
Intoplicine (RP 60475) dimesylate, an antitumor derivative in the 7H-benzo[e]pyrido[4,3-b]indole series, is a DNA topoisomerase I and II inhibitor. Intoplicine dimesylate strongly binds DNA (KA = 2 x 10 5 /M) and thereby increases the length of linear DNA .
|
-
- HY-147207
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 1000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207B
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 3400) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207D
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 10000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207E
-
|
Liposome
|
Others
|
Phospholipid-PEG-Biotin (MW 20000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-151640
-
|
ADC Linker
|
Others
|
Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies .
|
-
- HY-153840
-
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
ODN INH-18 is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 showes inhibitory potency for TLR9 ligand-induced IFN-α production.
|
-
- HY-153840A
-
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
ODN INH-18 sodium is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 sodium showes inhibitory potency for TLR9 ligand-induced IFN-α production.
|
-
- HY-E70097
-
|
Others
|
Others
|
Sialidase (α2-3-6-8-9) is a broadly specific sialidase that cuts linear and branched non-reducing terminal sialic acid residues from glycoproteins, glycopeptides, and oligosaccharides. Sialidase (α2-3-6-8-9) can be used for in vitro and in vivo polysaccharide analysis and characterization as well as complete glycoprotein remodeling .
|
-
- HY-E70094
-
|
DNA/RNA Synthesis
|
Others
|
T4 UvsX Recombinase helps initiate DNA replication on a double-stranded DNA template by catalyzing synapsis between the template and a homologous DNA single strand that serves as primer. T4 UvsX Recombinase greatly amplifies the snap-back (hairpin-primed) DNA synthesis that is catalyzed by the T4 DNA polymerase holoenzyme on linear, single-stranded DNA templates .
|
-
- HY-P4037
-
|
HCV
|
Infection
|
HCV Core Protein (107-114) is a least immunogenic residue of the major linear HCV core regions. HCV Core Protein (107-114) is identified as the binding site within the region 101-118, which contains two residues differing between genotypes Ⅰ/Ⅱ and Ⅲ/Ⅵ. HCV Core Protein (107-114) might be a potential site for dissemination of HCV serotypes .
|
-
- HY-P3571
-
|
Endothelin Receptor
|
Cancer
|
[Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3) where substitution of Ala for Cys residues. TE-3 is a vasoactive peptide, produced by human rhabdomyosarcoma cell lines, whereas it is not expressed by human sarcoma cell lines of non-muscle origin. ET-3 acts as a paracrine factor, since it promotes migration of endothelial cells .
|
-
- HY-122882
-
|
E1/E2/E3 Enzyme
|
Inflammation/Immunology
|
HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. HOIPIN-8 is a HOIPIN-1 derivative with enhanced the potency by 255-fold in the petit-LUBAC inhibition, and 10-fold and 4-fold in the LUBAC- and TNF-α-mediated NF-κB activation, respectively than HOIPIN-1. HOIPIN-1 is a promising tool to explore the cellular functions of LUBAC .
|
-
- HY-160062
-
|
Mucin
|
Cancer
|
S2.2 aptamer sodium is a nucleic acid aptamer targeting the mucin MUC1 and can be used for targeted imaging of MCF-7 cancer cells. S2.2 aptamer sodium was labeled with Cy5, and when fluorescent silicon nanodots (SiND) were present, the fluorescence was quenched; when MUC1 was also present, the fluorescence was restored. S2.2 aptamer sodium detects MUC1 with a linear range of 3.33-250 nM .
|
-
- HY-P5520
-
|
Bombesin Receptor
|
Cancer
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D1478
-
|
Fluorescent Dyes/Probes
|
Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .
|
Cat. No. |
Product Name |
Type |
-
- HY-D1005H
-
PEG-PPG-PEG, 8400(Average Mn)
|
Biochemical Assay Reagents
|
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models .
|
-
- HY-D1005A
-
PEG-PPG-PEG, 8800 (Average Mn)
|
Biochemical Assay Reagents
|
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models. Poloxamer 188 can be used for drug delivery .
|
-
- HY-W250110B
-
PEI (Linear, average Mn 2100, PDI<1.3)
|
Drug Delivery
|
Polyethylenimine (PEI) (linear, average Mn 2100, PDI<1.3), a cationic polymer, is a non-viral gene delivery vector, especially for oligonucleotide delivery .
|
-
- HY-125870
-
|
Biochemical Assay Reagents
|
Gellan gum is a linear microbial exopolysaccharide that can be used as a cell scaffold for both soft tissue and load bearing applications. Gellan gum has many advantages such as biocompatibility, biodegradability, nontoxic in nature, and physical stability in the presence of cations .
|
-
- HY-147207
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 1000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207B
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 3400) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207D
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 10000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
-
- HY-147207E
-
|
Drug Delivery
|
Phospholipid-PEG-Biotin (MW 20000) is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG-Biotin (MW 3400) can interact with avidinylated antibodies. Phospholipid-PEG-Biotin (MW 3400) can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P0173
-
|
Peptides
|
Cancer
|
Chlorotoxin(linear) is a linear 36 amino-acid peptide which can be used in Chlorotoxin related research.
|
-
- HY-P2081
-
|
Peptides
|
Others
|
Delicious peptide is a small linear octapeptide with delicious taste, can be isolated from the gravy of beef meat. Delicious peptide has savory flavor, is also described as beefy meaty peptide and a beef flavor enhancer .
|
-
- HY-P5085
-
|
Peptides
|
Others
|
Acetyl-octreotide is a reduced linear peptide. Acetyl-octreotide can synthesize Re(V)-cyclized peptides in aqueous methanol solutions with low Sst receptor binding affinities .
|
-
- HY-P0148
-
Hexaglycine
|
Peptides
|
Others
|
Gly6 (Hexaglycine) is a linear glycine oligopeptide with six glycines .
|
-
- HY-P0148A
-
Hexaglycine hydrochloride
|
Peptides
|
Others
|
Gly6 hydrochloride (Hexaglycine hydrochloride) is a linear glycine oligopeptide with six glycines .
|
-
- HY-P0290
-
GRGDSP
4 Publications Verification
|
Integrin
|
Cancer
|
GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
|
-
- HY-P1539
-
-
- HY-P3193A
-
|
Peptides
|
Others
|
Cyclic nona-L-arginine hydrochloride, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .
|
-
- HY-P3193
-
|
Peptides
|
Others
|
Cyclic nona-L-arginine TFA, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .
|
-
- HY-118090A
-
|
Peptides
|
Others
|
D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain .
|
-
- HY-P2318
-
|
Fungal
|
|
Bac2A TFA is an antimicrobial and immunomodulatory peptide. Bac2A TFA is a linear variant of bactenecin and is very effective against fungal pathogens.
|
-
- HY-P1203
-
-
- HY-P1203A
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- HY-P4006
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- HY-P1539A
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- HY-P1807
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Histamine Receptor
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Inflammation/Immunology
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Mast Cell Degranulating Peptide HR-2, a 14-membered linear peptide isolated from the venom of the giant hornet Vespa orientalis, is capable of degranulating mast cells and thus initiating histamine release .
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- HY-P1714
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FE 203799
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GLP Receptor
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Metabolic Disease
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Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
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- HY-P4115
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FABP
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Cancer
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CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles .
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- HY-P1714A
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FE 203799 TFA
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GLP Receptor
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Metabolic Disease
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Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
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- HY-P4324
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Peptides
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Cardiovascular Disease
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Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2 is a linear peptide from laminin B1 chain that interferes with tumor cell attachment and invasion into basement membrane and has anti-angiogenic effects .
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- HY-P3465
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Myrcludex B
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HBV
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Infection
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Bulevirtide (Myrcludex B) is a NTCP inhibitor, a linear lipopeptide of 47 amino acids. Bulevirtide inhibits HBV and HDV entry into liver cells, blocks HBV infection in hepatocytes, and participates in HBV transcriptional suppression. Bulevirtide can be used in HDV infection and compensated cirrhosis research .
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- HY-P1019A
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Endothelin Receptor
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Cardiovascular Disease
Endocrinology
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[Ala1,3,11,15]-Endothelin (53-63) (TFA) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) (TFA) has selectivity for ET B with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) (TFA) can be used for the research of vasoconstriction .
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- HY-P1019
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Endothelin Receptor
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Cardiovascular Disease
Endocrinology
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[Ala1,3,11,15]-Endothelin (53-63) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) has selectivity for ET B with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) can be used for the research of vasoconstriction
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- HY-P4896
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Integrin
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Cancer
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FITC-Ahx Gly Arg Gly Asp Ser Pro is a GRGDSP (HY-P0290) coupled to FITC. GRGDSP is an integrin inhibitor that can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis .
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- HY-P4037
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HCV
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Infection
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HCV Core Protein (107-114) is a least immunogenic residue of the major linear HCV core regions. HCV Core Protein (107-114) is identified as the binding site within the region 101-118, which contains two residues differing between genotypes Ⅰ/Ⅱ and Ⅲ/Ⅵ. HCV Core Protein (107-114) might be a potential site for dissemination of HCV serotypes .
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- HY-P3571
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Endothelin Receptor
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Cancer
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[Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3) where substitution of Ala for Cys residues. TE-3 is a vasoactive peptide, produced by human rhabdomyosarcoma cell lines, whereas it is not expressed by human sarcoma cell lines of non-muscle origin. ET-3 acts as a paracrine factor, since it promotes migration of endothelial cells .
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- HY-P5509
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Peptides
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Others
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C5aR1 antagonist peptide is a biological active peptide. (This linear peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions to inhibit C5a binding and function at human and rat C5a receptors. C5a is crucial to triggering cellular immune responses and its overexpression is involved in arthritis, Alzheimer’s disease, cystic fibrosis, systemic lupus erythematosus, and other immunoinflammatory diseases.)
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- HY-P5520
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Bombesin Receptor
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Cancer
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GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
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- HY-P5415
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Peptides
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Others
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DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. (DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is also called HIV protease substrate I in some literature. It is widely used for the continuous assay for HIV protease activity. The 11-kD protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. The FRET-based fluorogenic substrate is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that is linearly related to the extent of substrate hydrolysis. The fluorescence quantum yields of the HIV-1 PR substrate in the FRET assay increased by 40.0- and 34.4-fold, respectively, per mole of substrate cleaved. Because of its simplicity and precision in the determination of reaction rates required for kinetic analysis, this substrate offers many advantages over the commonly used HPLC or electrophoresis-based assays for peptide substrate hydrolysis by retroviral PRs. Abs/Em = 340nm/490nm.)
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- HY-KE7055
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RNase R is a magnesium ion-dependent 3'-5' exoribonuclease that can increase the abundance of circular RNA by degrading linear RNA in mixed RNA, thereby enriching circular RNA.
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Product Name |
Category |
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Chemical Structure |
Cat. No. |
Product Name |
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Classification |
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- HY-151640
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Azide
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Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies .
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