L-Triguluronic acid

Name: L-Triguluronic acid
Brand: MedChemExpress
SKU: HY-N7701A
Rating: 4.5 (1 reviews)

Cat. No.: HY-N7701A Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Triguluronic acid is a linear polysaccharide copolymer composed of three L-guluronic acid (G) and can be used to from Alginate. Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of anti-fungal agents delivery carries.

For research use only. We do not sell to patients.

L-Triguluronic acid Chemical Structure

CAS No. : 66754-14-1

Size	Price	Stock	Quantity
5 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Triguluronic acid:

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Biological Activity
Purity & Documentation
References
Customer Review

Description

L-Triguluronic acid is a linear polysaccharide copolymer composed of three L-guluronic acid (G) and can be used to from Alginate^[1]. Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of anti-fungal agents delivery carries^[2].

In Vitro

Alginate is a generic name assigned to a series of polyanionic polysaccharides of β-d-mannuronic acid (M) and α-l-guluronic acid (G). Alginate is linked by a 1→4 linkage and displaying chain homosequences of MMM and GGG, interdispersed with MGM heterosequences^[1].
Alginate is widely used for obtainment of drug delivery systems due to its non-toxicity, biodegradability, biocompatibility, mucoadhesive, and non-immunogenic properties. Additionally, alginate-based antifungal delivery systems have great potential in the treatment of fungal infections in vivo^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

546.39

Formula

C₁₈H₂₆O₁₉

CAS No.

66754-14-1

Appearance

Solid

Color

Off-white to light yellow

SMILES

OC([C@H](O[C@H]1O[C@@H]([C@@H]([C@@H]2O)O)[C@@H](O[C@H]2O)C(O)=O)[C@H]([C@@H]([C@@H]1O)O)O[C@@H]([C@H]([C@H]3O)O)O[C@H]([C@H]3O)C(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 250 mg/mL (457.55 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8302 mL	9.1510 mL	18.3019 mL
5 mM	0.3660 mL	1.8302 mL	3.6604 mL
10 mM	0.1830 mL	0.9151 mL	1.8302 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (280 KB) SDS (251 KB)

COA (260 KB) HNMR (265 KB) MS (175 KB)

Handling Instructions (2659 KB)

References

[1]. Cristina de Castro Spadari, et al. Potential Use of Alginate-Based Carriers As Antifungal Delivery System.Front Microbiol. 2017 Jan 30;8:97. [Content Brief]

[2]. R.A. Shirwaiker, et al. L-Guluronic Acid

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.8302 mL	9.1510 mL	18.3019 mL	45.7549 mL
	5 mM	0.3660 mL	1.8302 mL	3.6604 mL	9.1510 mL
	10 mM	0.1830 mL	0.9151 mL	1.8302 mL	4.5755 mL
	15 mM	0.1220 mL	0.6101 mL	1.2201 mL	3.0503 mL
	20 mM	0.0915 mL	0.4575 mL	0.9151 mL	2.2877 mL
	25 mM	0.0732 mL	0.3660 mL	0.7321 mL	1.8302 mL
	30 mM	0.0610 mL	0.3050 mL	0.6101 mL	1.5252 mL
	40 mM	0.0458 mL	0.2288 mL	0.4575 mL	1.1439 mL
	50 mM	0.0366 mL	0.1830 mL	0.3660 mL	0.9151 mL
	60 mM	0.0305 mL	0.1525 mL	0.3050 mL	0.7626 mL
	80 mM	0.0229 mL	0.1144 mL	0.2288 mL	0.5719 mL
	100 mM	0.0183 mL	0.0915 mL	0.1830 mL	0.4575 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.