1. Cytoskeleton
  2. Integrin
  3. GRGDSP

GRGDSP 

Cat. No.: HY-P0290
Handling Instructions

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GRGDSP Chemical Structure

GRGDSP Chemical Structure

CAS No. : 91037-75-1

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Description

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

IC50 & Target

Integrin[1]

In Vitro

It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis[1]. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

587.58

Formula

C₂₂H₃₇N₉O₁₀

CAS No.

91037-75-1

Sequence

Gly-Arg-Gly-Asp-Ser-Pro

Sequence Shortening

GRGDSP

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

GRGDSPIntegrinInhibitorinhibitorinhibit

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