1. GPCR/G Protein
  2. Endothelin Receptor
  3. [Ala2] Endothelin-3, human

[Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3) where substitution of Ala for Cys residues. TE-3 is a vasoactive peptide, produced by human rhabdomyosarcoma cell lines, whereas it is not expressed by human sarcoma cell lines of non-muscle origin. ET-3 acts as a paracrine factor, since it promotes migration of endothelial cells.

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[Ala2] Endothelin-3, human Chemical Structure

[Ala2] Endothelin-3, human Chemical Structure

CAS No. : 2243207-08-9

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Description

[Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3) where substitution of Ala for Cys residues. TE-3 is a vasoactive peptide, produced by human rhabdomyosarcoma cell lines, whereas it is not expressed by human sarcoma cell lines of non-muscle origin. ET-3 acts as a paracrine factor, since it promotes migration of endothelial cells[1][2].

Molecular Weight

2613.02

Formula

C120H166N26O32S4

CAS No.
Sequence

Cys-Ala-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)

Sequence Shortening

CACFTYKDKECVYYCHLDIIW (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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[Ala2] Endothelin-3, human Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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[Ala2] Endothelin-3, human
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