2243207-08-9
![[Ala2] Endothelin-3, human Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-p3571.gif "[Ala2] Endothelin-3, human Chemical Structure")
Chemical Structure
[Ala2] Endothelin-3, human
- CAS No.: 2243207-08-9
- Formula:C120H166N26O32S4
- Molecular Weight:2613.02
SMILES: O=C([C@@H](N)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC2=CNC3=CC=CC=C23)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(C)C)=O)CC4=CNC=N4)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]5CCC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)CCCCN)=O)CC6=CC=C(O)C=C6)=O)[C@@H](C)O)=O)CC7=CC=CC=C7)=O)CSSC[C@H](NC5=O)C(N[C@H](C(N[C@H](C(N[C@H]1CC8=CC=C(O)C=C8)=O)CC9=CC=C(O)C=C9)=O)C(C)C)=O)=O)C
Biological Activity: [Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3) where substitution of Ala for Cys residues. TE-3 is a vasoactive peptide, produced by human rhabdomyosarcoma cell lines, whereas it is not expressed by human sarcoma cell lines of non-muscle origin. ET-3 acts as a paracrine factor, since it promotes migration of endothelial cells[1][2].
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[Ala2] Endothelin-3, human | [Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3) where substitution of Ala for Cys residues. TE-3 is a vasoactive peptide, produced by human rhabdomyosarcoma cell lines, whereas it is not expressed by human sarcoma cell lines of non-muscle origin. ET-3 acts as a paracrine factor, since it promotes migration of endothelial cells. | |||||||||||||||||||||
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